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BOC-CYS-OH

BOC-CYS-OH structure

CAS No.: 20887-95-0

Chemical Name:: BOC-CYS-OH

Synonyms: BOC-CYS-OH;BOC-L-CYS-OH;BOC-L-CYSTEINE;N-Boc-L-cysteine;Boc-Cys-Cysteine;BOC-CYS-OH USP/EP/BP;N-ALPHA-T-BOC-L-CYSTEINE;Boc-Cys-OH,Boc-L-cysteine;Boc-L-cysteine≥ 98% (HPLC);Boc-Cys-OH (cryst) Novabiochem

CBNumber:: CB1153365

Molecular Formula:: C8H15NO4S

Molecular Weight:: 221.27

MDL Number:: MFCD00065565

MOL File:: 20887-95-0.mol

MSDS File:: SDS

Last updated:2026-01-13 11:14:14

Product description	Number	Pack Size	Price
Boc-Cys-OH (cryst) Novabiochem?	8.53031	5G	$266
Boc-Cys-OH (cryst) Novabiochem?	8.53031	25G	$982
Boc-Cys-OH for chiral derivatization, ≥98.5%	15411	250mg	$84
Boc-Cys-OH for chiral derivatization, ≥98.5%	15411	1g	$314
Boc-L-cysteine	264624	1g	$319
More product size

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BOC-CYS-OH Properties

Melting point	67-70°C
Boiling point	361.4±37.0 °C(Predicted)
Density	1?+-.0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,2-8°C
solubility	DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol
pka	3.57±0.10(Predicted)
form	Solid
color	White to Off-White
optical activity	[α]20/D +8.0±1.5°, c = 1% in ethanol
BRN	2450705
InChI	InChI=1S/C8H15NO4S/c1-8(2,3)13-7(12)9-5(4-14)6(10)11/h5,14H,4H2,1-3H3,(H,9,12)(H,10,11)/t5-/m0/s1
InChIKey	ATVFTGTXIUDKIZ-YFKPBYRVSA-N
SMILES	C(O)(=O)[C@H](CS)NC(OC(C)(C)C)=O
CAS DataBase Reference	20887-95-0(CAS DataBase Reference)
UNSPSC Code	41116105
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08,GHS09
Signal word	Danger
Hazard statements	H315-H319-H413-H372
Precautionary statements	P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
PPE	Eyeshields, Gloves, type N95 (US)
Safety Statements	24/25
WGK Germany	3
HS Code	29309090
Storage Class	13 - Non Combustible Solids

BOC-CYS-OH price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.53031	Boc-Cys-OH (cryst) Novabiochem?	20887-95-0	5G	$266	2025-07-31	Buy
Sigma-Aldrich	8.53031	Boc-Cys-OH (cryst) Novabiochem?	20887-95-0	25G	$982	2023-06-20	Buy
Sigma-Aldrich	15411	Boc-Cys-OH for chiral derivatization, ≥98.5%	20887-95-0	250mg	$84	2022-05-15	Buy
Sigma-Aldrich	15411	Boc-Cys-OH for chiral derivatization, ≥98.5%	20887-95-0	1g	$314	2022-05-15	Buy
Usbiological	264624	Boc-L-cysteine	20887-95-0	1g	$319	2021-12-16	Buy

Product number	Packaging	Price	Buy
8.53031	5G	$266	Buy
8.53031	25G	$982	Buy
15411	250mg	$84	Buy
15411	1g	$314	Buy
264624	1g	$319	Buy

BOC-CYS-OH Chemical Properties,Uses,Production

Chemical Properties

light yellowliquid

Uses

Boc-L-cysteine is the protected form of L-Cysteine (C995000), a non-essential α-amino acid that is biosynthesized in humans. L-Cysteine is also a bicarbonate-sensitive endogenous excitotoxin in rats and possibly humans.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

10389-65-8

20887-95-0

General procedure for the synthesis of (R)-2-((tert-butoxycarbonyl)amino)-3-mercaptopropionic acid from N,N'-bis(Boc)-L-cystine: N,N'-bis(Boc)-L-cystine (2.51 mmol) was dissolved in a solvent mixture of tetrahydrofuran (29.2 mL) and water (0.8 mL). Tributylphosphine (2.76 mmol) was added to the solution under ice bath cooling conditions. The reaction mixture was gradually warmed up to room temperature and stirred continuously at this temperature for 1 hour. Upon completion of the reaction, ethyl acetate (20 mL) and 10% aqueous citric acid (10 mL) were added to the reaction mixture for extraction and separation. The organic phase was collected and washed with saturated aqueous saline solution (20 mL). Subsequently, the organic phase was concentrated and the resulting residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate mixed solvent) to afford the target compound 22 as an oily product. Yield: 99%. ESI MS m/z 220.1 [M-H]-; 1H NMR (400 MHz, CDCl3) δ: 5.47 (1H, brs), 4.65 (1H, brs), 3.09-2.97 (2H, m), 1.48 (9H, s).

References

[1] Patent: US2012/282386, 2012, A1. Location in patent: Page/Page column 15
[2] Journal of Nanoparticle Research, 2017, vol. 19, # 6,
[3] Angewandte Chemie, 1993, vol. 105, # 2, p. 311 - 313
[4] Chemische Berichte, 1969, vol. 102, p. 1048 - 1052
[5] Protein and Peptide Letters, 2014, vol. 21, # 12, p. 1257 - 1264

BOC-CYS-OH synthesis

Synthesis of BOC-CYS-OH from L-Cysteine and Di-tert-butyl dicarbonate

BOC-CYS-OH Preparation Products And Raw materials

Raw materials

BOC-CYS(ACM)-OH methyl 2-((tert-butoxycarbonyl)amino)-3-mercaptopropanoate (BOC-CYS-OH)2 N-Boc-Benzotriazole Boc-S-(4-methylbenzyl)-L-cysteine

BOC-CYS(4-MEOBZL)-OH Boc-S-Benzyl-L-cysteine L-Cysteine Di-tert-butyl dicarbonate L-Cysteine monohydrochloride

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Preparation Products

2-Pyridinethione 2-Hydroxypyridine 3-Nitro-2-pyridinethiol

BOC-CYS-OH Suppliers

Global( 186)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5242	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29832	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	58
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Accela ChemBio Inc.	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58

View Lastest Price from BOC-CYS-OH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-05-26	BOC-CYS-OH 20887-95-0	US $2.60 / KG	1KG	99%	5000kg	Hebei Chuanghai Biotechnology Co,.LTD
2021-08-12	BOC-CYS-OH 20887-95-0	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-09-02	BOC-CYS-OH 20887-95-0	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

BOC-CYS-OH
20887-95-0
US $2.60 / KG
99%
Hebei Chuanghai Biotechnology Co,.LTD

BOC-CYS-OH
20887-95-0
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

BOC-CYS-OH
20887-95-0
US $7.00 / KG
99%
Career Henan Chemical Co

BOC-CYS-OH Spectrum

BOC-CYS-OH(20887-95-0)¹HNMR BOC-CYS-OH(20887-95-0)¹HNMR BOC-CYS-OH(20887-95-0)FT-IR

20887-95-0(BOC-CYS-OH)Related Search:

BOC-CYS(ET)-OH BOC-CYS-OH BOC-CYS(4-MEOBZL)-OH BOC-S-TERT-BUTYLMERCAPTO-L-CYSTEINE BOC-CYS(ME)-OH

BOC-L-THIAZOLIDINE-4-CARBOXYLIC ACID BOC-CYS(ACM)-OH BOC-PEN(MOB)-OH Boc-S-Benzyl-L-cysteine Boc-S-(4-methylbenzyl)-L-cysteine

(Boc-Cys-OH)2 (Disulfide bond),(BOC-CYS-OH)2 N-Boc-S-Trityl-L-cysteine BOC-CYS(DPM)-OH BOC-CYS(TBU)-OH BOC-CYS(FM)-OH

BOC-S-(4-METHOXYBENZYL)-L-CYSTEINE DICYCLOHEXYLAMINE SALT BOC-CYS(BZL)-ONP BOC-CYS(3,4-DIMETHYLBENZYL)-OH

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N-[(tert-Butyloxy)carbonyl]-L-cysteine (S)-2-tert-Butoxycarbonylamino-3-mercapto-propionic acid (2R)-2-(tert-butoxycarbonylamino)-3-mercapto-propionic acid (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-sulfanylpropanoic acid (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-sulfanyl-propanoic acid Boc-Cys-OH,Boc-L-cysteine (2R)-2-[(tert-butoxycarbonyl)aMino]-3-sulfanylpropanoic acid N-Boc-L-cysteine (R)-2-((tert-butoxycarbonyl)aMino)-3-Mercaptopropanoic acid Boc-L-cysteine, for chiral derivatization Boc-L-cysteine≥ 98% (HPLC) Boc-Cys-OH (cryst) Novabiochem N-ALPHA-T-BUTOXYCARBONYL-L-CYSTEINE N-ALPHA-T-BUTYLOXYCARBONYL-L-CYSTEINE N-ALPHA-TERT-BUTYLOXYCARBONYL-L-CYSTEINE N-ALPHA-T-BOC-L-CYSTEINE BOC-CYS-OH BOC-L-CYSTEINE BOC-L-CYS-OH N-(tert-Butoxycarbonyl)-L-cysteine N-tert-butyloxycarbonylcysteine N-(tert-Butyloxycarbonyl)-L-cysteine Boc-L-cysteine, 98%, for chiral derivatization L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]- (2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-sulfanylpropanoicaci BOC-CYS-OH USP/EP/BP Boc-Cys-Cysteine (2R)-2-(tert-butoxycarbonylamino)-3-sulfanyl-propanoic acid - [B84635] 20887-95-0 Cysteine/Cystine Specialty Synthesis Peptide Synthesis Amino Acid Derivatives Boc-Amino acid series Amino Acids Pharmaceutical Intermediates