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Nonylphenol Ethoxylate

CAS No.
9016-45-9
Chemical Name:
Nonylphenol Ethoxylate
Synonyms
TX-10;Ethoxylated nonylphenol;NP 40;ethyleneoxy;Nonylphenol polyoxyethylene ether;Nonoxynols;TX-9;TX-21;Nonoxinol;Nonylphenoxypoly(ethyleneoxy)ethanol
CBNumber:
CB1159958
Molecular Formula:
C19H32O3
Molecular Weight:
308.45558
MDL Number:
MFCD08460582
MOL File:
9016-45-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-24 18:39:39

Nonylphenol Ethoxylate Properties

Melting point 44-46 °C
Boiling point 250 °C(lit.)
Density 1.06 g/mL at 20 °C
vapor pressure 1.4hPa at 25℃
refractive index n20/D 1.495(lit.)
Flash point 535 °F
storage temp. -20°C
form Clear, colorless liquid
color clear colorless
PH 5-8 (5% in H2O)
biological source rabbit
Viscosity 350-450mPa.s(20°C)
Water Solubility water: 25mg/mL
aqueous buffer: soluble
Specific Activity 613-829nmol/min·mg
Cosmetics Ingredients Functions SURFACTANT - SOLUBILIZING
SURFACTANT - EMULSIFYING
SURFACTANT - CLEANSING
Cosmetic Ingredient Review (CIR) Nonylphenol Ethoxylate (9016-45-9)
InChI InChI=1S/C19H32O3/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)22-17-16-21-15-14-20/h10-13,20H,2-9,14-17H2,1H3
InChIKey BLXVTZPGEOGTGG-UHFFFAOYSA-N
SMILES C(O)COCCOC1=CC=C(CCCCCCCCC)C=C1
LogP 3.7-4.48 at 25℃
Surface tension 32.3mN/m at 1g/L and 20℃
Substances of Very High Concern (SVHC) Candidate List Nonylphenol, ethoxylated (9016-45-9)
REACH Annex XVII Substances List Nonylphenol, ethoxylated (9016-45-9)
FDA 21 CFR 177.1632
Indirect Additives used in Food Contact Substances POLY(OXYETHYLENE) MONO(NONYLPHENYL) ETHER
CAS DataBase Reference 9016-45-9
EWG's Food Scores 2-4
FDA UNII 6FW840C8W9
EPA Substance Registry System Polyethylene glycol nonylphenyl ether (9016-45-9)
UNSPSC Code 12352300
NACRES NA.41

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Environment (GHS09)
GHS07,GHS09
Signal word  Warning
Hazard statements  H315-H319-H412
Precautionary statements  P273-P302+P352-P305+P351+P338
Hazard Codes  Xi,N,Xn
Risk Statements  41-38-37-36/37/38-50-22
Safety Statements  26-39-36-61
RIDADR  UN 3082 9 / PGIII
WGK Germany  2
RTECS  WZ4750000
3
TSCA  TSCA listed
HS Code  34021300
Storage Class 10 - Combustible liquids
Hazard Classifications Aquatic Chronic 2
Eye Irrit. 2
Skin Irrit. 2
Hazardous Substances Data 9016-45-9(Hazardous Substances Data)
Toxicity LD50 oral in rat: 2590uL/kg
REACH Registrations Inactive

Nonylphenol Ethoxylate price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 492018 NP-40 Alternative, PROTEIN GRADE Detergent, 10% Solution, Sterile-Filtered - CAS 9016-45-9 - Calbiochem 9016-45-9 500mL $1200 2026-04-30 Buy
Sigma-Aldrich SAB1305267 ANTI-RAB9P40(C-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution 400μL $496 2025-07-31 Buy
Sigma-Aldrich E1283 ERK2, active, GST tagged human recombinant, expressed in E. coli, PRECISIO? Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution 9016-45-9 10μg $564 2025-07-31 Buy
Usbiological 566953 LANCL1 PurifiedbyProteinGaffinitychromatography. 50ug $509 2026-06-03 Buy
Usbiological 566953 LANCL1 PurifiedbyProteinGaffinitychromatography. 100ug $708 2026-06-03 Buy
Product number Packaging Price Buy
492018 500mL $1200 Buy
SAB1305267 400μL $496 Buy
E1283 10μg $564 Buy
566953 50ug $509 Buy
566953 100ug $708 Buy

Nonylphenol Ethoxylate Chemical Properties,Uses,Production

Description

Nonylphenol Ethoxylate, also known as NPEs, are nonionic surfactants that are liquid in form. Many different types of NPEs are determined by the number of moles of Ethylene Oxide, or EO. NPEs may function as adjuvants, cleaners, detergents, dispersants, emulsifiers, humectants, solubilizers or wetting agents. Nonylphenol Ethoxylates are used in many applications, including coatings, crop solutions, functional fluids, household, industrial, and institutional cleaning, as well as oil and gas.

Uses

NP40 Cell Lysis Buffer is suitable for the preparation of cell extracts to be analyzed by Antibody Bead Immunoassay (Luminex), ELISA, and Western blotting. It can also be used as a wash buffer for immunoprecipitation reactions.

Uses

Arkopal N 100 is a nonionic surfactant that can be used for testing the stress cracking resistance of polyethylene materials at high temperatures. It is also suitable for enhancing the biodegradation of aromatic hydrocarbon compounds.

General Description

with approx. 10 ethylene oxide units

Biochem/physiol Actions

ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

Safety Profile

Moderately toxic by ingestion and skin contact. A severe eye and mild skin irritant in humans. Many glycol ethers cause dangerous human reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS.

Toxics Screening Level

The initial threshold screening level (ITSL) for Igepal CO-630 is 18 μg/m3 based on an annual averaging time.

Global( 405)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Dingfen Chemical Technology Co., Ltd. 021-57450129 17701764569 369405814@qq.com China 7341 58
Chengdu HuaXia Chemical Reagent Co. Ltd 400-1166-196 13458535857 cdhxsj@163.com China 13323 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29676 58
Pand (Shanghai) international trade Co., LTD 80159919 18662931292 3404730042@qq.com China 4978 58
Suzhou Jadechem New Materials Co., Ltd. 0512-6599 1069 15382515953 853154468@qq.com China 70 58
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57

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View Lastest Price from Nonylphenol Ethoxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Nonylphenoxypoly(ethyleneoxy)ethanol pictures 2026-05-28 Nonylphenoxypoly(ethyleneoxy)ethanol
9016-45-9
$2.00-5.00 1KG 99% 10000kg Hebei Chuanghai Biotechnology Co,.LTD
Nonylphenol ethoxylate pictures 2026-05-08 Nonylphenol ethoxylate
9016-45-9
$1400.00-1600.00 10ton 99% 100 ton ChemFine International Co.,Ltd.
Nonylphenoxypoly(ethyleneoxy)ethanol pictures 2025-06-20 Nonylphenoxypoly(ethyleneoxy)ethanol
9016-45-9
1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
NONIDET P- 40 SUBSTITUTE NP-40 NP-10(Nonylphenyl-polyethylene glycol solution) NP-12(Nonylphenyl-polyethylene glycol solution) NP-15(Nonylphenyl-polyethylene glycol solution) NP-20(Nonylphenyl-polyethylene glycol solution) NP-4(Nonylphenyl-polyethylene glycol solution) NP-40(Nonylphenyl-polyethylene glycol solution) NP-50(Nonylphenyl-polyethylene glycol solution) NP 40 NP-40 Substitute Octylphenoxypolyethoxyethanol Nonoxinol(CP2000) LUTENSOL AP 20 FOR GC IGEPAL CO 990 FOR GC TERGITOL(R) NPX* NONIDET P 40 SUBSTITUTE SOL, ~10% IN H2O, PGE W 6X10 ML SYNPERONIC NP 5 NonylPhenol95 ProteinSolubilizer40,ReadytouseAmpules,Sterile Poly(oxy-1,2-ethanediyl), .alpha.-(nonylphenyl)-.omega.-hydroxy- imbentin-n/52solution nonidet p 40substitute solution NONIDETP40SOLUTION NONYLPHENOXY-POLYETHOXYETHANOL POLYALKOXYLATEDALKYLPHENOL NONYLPHENOLMONOETHOXYLATE ETHOXYLATEDNONYLPHENYLETHER POLYOXYETHYLENE-20-NONYLPHENOL RENEX698 POLYETHYLENEGLYCOLNONYLPHENOLETHER NONYLPHENOLDODECYLETHOXYLATE POLYOXYETHYLENE-100-NONYLPHENOL NP12EO 4-Nonylphenyl-polyethylene glycol, Imbentin-N/63 Synperonic(R) NP 5 4-Nonylphenyl-polyethylene glycol TX-13 TX-18 TX-4;TX-5; TX-6; TX-7; TX-8; TX-9; TX-10; TX-13; TX-15; TX-18; TX-21; TX-40; TX-40 TX-5 TX-6 TX-8 TX-9 NP-40 SUBSTITUTE TERGITOL NP X Nonoxinol Tergitol NP-33 NONOXYNOL-25 NONIDET P 40 SUBSTITUTE SOL, ~10% INH2O Protein Solubilizer 40, Sterile 10% of NP-40, Ready to use AMpules IGEPAL CO-520,Polyoxyethylene (5) nonylphenylether, branched IGEPAL CO-720,Polyoxyethylene (12) nonylphenyl ether, branched IGEPAL CO-890,Polyoxyethylene (40) nonylphenyl ether, branched IGEPAL CO-630,Polyoxyethylene (9) nonylphenylether, branched Arkopal N 100 Nonidet(R) P40 Solution Poly(oxy-1,2-ethanediyl), α-(nonylphenyl)-ω-hydroxy- Poly(oxy-1,2-ethanediyl),a-(nonylphenyl)-w-hydroxy-