Nonylphenol Ethoxylate
- CAS No.
- 9016-45-9
- Chemical Name:
- Nonylphenol Ethoxylate
- Synonyms
- TX-10;Ethoxylated nonylphenol;NP 40;ethyleneoxy;Nonylphenol polyoxyethylene ether;Nonoxynols;TX-9;TX-21;Nonoxinol;Nonylphenoxypoly(ethyleneoxy)ethanol
- CBNumber:
- CB1159958
- Molecular Formula:
- C19H32O3
- Molecular Weight:
- 308.45558
- MDL Number:
- MFCD08460582
- MOL File:
- 9016-45-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 44-46 °C |
|---|---|
| Boiling point | 250 °C(lit.) |
| Density | 1.06 g/mL at 20 °C |
| vapor pressure | 1.4hPa at 25℃ |
| refractive index |
n |
| Flash point | 535 °F |
| storage temp. | -20°C |
| form | Clear, colorless liquid |
| color | clear colorless |
| PH | 5-8 (5% in H2O) |
| biological source | rabbit |
| Viscosity | 350-450mPa.s(20°C) |
| Water Solubility |
water: 25mg/mL aqueous buffer: soluble |
| Specific Activity | 613-829nmol/min·mg |
| Cosmetics Ingredients Functions |
SURFACTANT - SOLUBILIZING SURFACTANT - EMULSIFYING SURFACTANT - CLEANSING |
| Cosmetic Ingredient Review (CIR) | Nonylphenol Ethoxylate (9016-45-9) |
| InChI | InChI=1S/C19H32O3/c1-2-3-4-5-6-7-8-9-18-10-12-19(13-11-18)22-17-16-21-15-14-20/h10-13,20H,2-9,14-17H2,1H3 |
| InChIKey | BLXVTZPGEOGTGG-UHFFFAOYSA-N |
| SMILES | C(O)COCCOC1=CC=C(CCCCCCCCC)C=C1 |
| LogP | 3.7-4.48 at 25℃ |
| Surface tension | 32.3mN/m at 1g/L and 20℃ |
| Substances of Very High Concern (SVHC) Candidate List | Nonylphenol, ethoxylated (9016-45-9) |
| REACH Annex XVII Substances List | Nonylphenol, ethoxylated (9016-45-9) |
| FDA 21 CFR | 177.1632 |
| Indirect Additives used in Food Contact Substances | POLY(OXYETHYLENE) MONO(NONYLPHENYL) ETHER |
| CAS DataBase Reference | 9016-45-9 |
| EWG's Food Scores | 2-4 |
| FDA UNII | 6FW840C8W9 |
| EPA Substance Registry System | Polyethylene glycol nonylphenyl ether (9016-45-9) |
| UNSPSC Code | 12352300 |
| NACRES | NA.41 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H412 |
| Precautionary statements | P273-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi,N,Xn |
| Risk Statements | 41-38-37-36/37/38-50-22 |
| Safety Statements | 26-39-36-61 |
| RIDADR | UN 3082 9 / PGIII |
| WGK Germany | 2 |
| RTECS | WZ4750000 |
| F | 3 |
| TSCA | TSCA listed |
| HS Code | 34021300 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Aquatic Chronic 2 Eye Irrit. 2 Skin Irrit. 2 |
| Hazardous Substances Data | 9016-45-9(Hazardous Substances Data) |
| Toxicity | LD50 oral in rat: 2590uL/kg |
| REACH Registrations | Inactive |
Nonylphenol Ethoxylate price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 492018 | NP-40 Alternative, PROTEIN GRADE Detergent, 10% Solution, Sterile-Filtered - CAS 9016-45-9 - Calbiochem | 9016-45-9 | 500mL | $1200 | 2026-04-30 | Buy |
| Sigma-Aldrich | SAB1305267 | ANTI-RAB9P40(C-TERMINAL) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 400μL | $496 | 2025-07-31 | Buy | |
| Sigma-Aldrich | E1283 | ERK2, active, GST tagged human recombinant, expressed in E. coli, PRECISIO? Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution | 9016-45-9 | 10μg | $564 | 2025-07-31 | Buy |
| Usbiological | 566953 | LANCL1 PurifiedbyProteinGaffinitychromatography. | 50ug | $509 | 2026-06-03 | Buy | |
| Usbiological | 566953 | LANCL1 PurifiedbyProteinGaffinitychromatography. | 100ug | $708 | 2026-06-03 | Buy |
Nonylphenol Ethoxylate Chemical Properties,Uses,Production
Description
Nonylphenol Ethoxylate, also known as NPEs, are nonionic surfactants that are liquid in form. Many different types of NPEs are determined by the number of moles of Ethylene Oxide, or EO. NPEs may function as adjuvants, cleaners, detergents, dispersants, emulsifiers, humectants, solubilizers or wetting agents. Nonylphenol Ethoxylates are used in many applications, including coatings, crop solutions, functional fluids, household, industrial, and institutional cleaning, as well as oil and gas.
Uses
NP40 Cell Lysis Buffer is suitable for the preparation of cell extracts to be analyzed by Antibody Bead Immunoassay (Luminex), ELISA, and Western blotting. It can also be used as a wash buffer for immunoprecipitation reactions.
Uses
Arkopal N 100 is a nonionic surfactant that can be used for testing the stress cracking resistance of polyethylene materials at high temperatures. It is also suitable for enhancing the biodegradation of aromatic hydrocarbon compounds.
General Description
with approx. 10 ethylene oxide units
Biochem/physiol Actions
ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).
Safety Profile
Moderately toxic by ingestion and skin contact. A severe eye and mild skin irritant in humans. Many glycol ethers cause dangerous human reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS.
Toxics Screening Level
The initial threshold screening level (ITSL) for Igepal CO-630 is 18 μg/m3 based on an annual averaging time.
Nonylphenol Ethoxylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Dingfen Chemical Technology Co., Ltd. | 021-57450129 17701764569 | 369405814@qq.com | China | 7341 | 58 |
| Chengdu HuaXia Chemical Reagent Co. Ltd | 400-1166-196 13458535857 | cdhxsj@163.com | China | 13323 | 58 |
| Shanghai Maclean Biochemical Technology Co., LTD | 021-50706066 15221275939 | shenlinxing@macklin.cn | China | 29676 | 58 |
| Pand (Shanghai) international trade Co., LTD | 80159919 18662931292 | 3404730042@qq.com | China | 4978 | 58 |
| Suzhou Jadechem New Materials Co., Ltd. | 0512-6599 1069 15382515953 | 853154468@qq.com | China | 70 | 58 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
Related articles
- Toxicity and Application of Nonylphenol ethoxylate
- Nonylphenol ethoxylate (NPE) is the most important alkylphenol ethoxylate. NPE accounts for approximately 85% of alkylphenol e....
- Mar 21,2022
View Lastest Price from Nonylphenol Ethoxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-28 | Nonylphenoxypoly(ethyleneoxy)ethanol
9016-45-9
|
$2.00-5.00 | 1KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
![]() |
2026-05-08 | Nonylphenol ethoxylate
9016-45-9
|
$1400.00-1600.00 | 10ton | 99% | 100 ton | ChemFine International Co.,Ltd. | |
![]() |
2025-06-20 | Nonylphenoxypoly(ethyleneoxy)ethanol
9016-45-9
|
1kg | 0.99 | 20 tons | Hebei Yanxi Chemical Co., Ltd. |
-

- Nonylphenoxypoly(ethyleneoxy)ethanol
9016-45-9
- $2.00-5.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-

- Nonylphenol ethoxylate
9016-45-9
- $1400.00-1600.00
- 99%
- ChemFine International Co.,Ltd.
-

- Nonylphenoxypoly(ethyleneoxy)ethanol
9016-45-9
- $0.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.






