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Fluazinam

CAS No.
79622-59-6
Chemical Name:
Fluazinam
Synonyms
fluaziname;Fluazinam Standard;3-Chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluoro-2,6-dinitro-p-toluidine;3-Chloro-N-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)pyridin-2-amine;pp192;Mapro;B 1216;AltiMa;Sekoya;SHIRLAN
CBNumber:
CB1161197
Molecular Formula:
C13H4Cl2F6N4O4
Molecular Weight:
465.09
MDL Number:
MFCD00214168
MOL File:
79622-59-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-03 11:24:09
Product description Number Pack Size Price
Fluazinam PESTANAL , analytical standard 34095 100mg $146
Fluazinam >98.0%(HPLC)(T) F0869 1g $140
Fluazinam ≥95% 36221 500mg $54
Fluazinam ≥95% 36221 1g $86
Fluazinam ≥95% 36221 5g $203
More product size

Fluazinam Properties

Melting point 100-102°
Boiling point 376.1±42.0 °C(Predicted)
Density 1.766±0.06 g/cm3(Predicted)
vapor pressure 1.5 x 10-3 Pa (25 °C)
Flash point 2 °C
storage temp. 2-8°C
solubility DMF:25.0(Max Conc. mg/mL);53.75(Max Conc. mM)
DMSO:25.0(Max Conc. mg/mL);53.75(Max Conc. mM)
Ethanol:15.0(Max Conc. mg/mL);32.25(Max Conc. mM)
PBS (pH: 7.2):0.25(Max Conc. mg/mL);0.54(Max Conc. mM)
form Solid
pka 7.11(at 25℃)
Water Solubility 1.7 mg l-1 (25 °C)
color Light yellow to Amber to Dark green
Merck 14,4117
BRN 4772672
Henry's Law Constant 3.9×10-2 mol/(m3Pa) at 25℃, HSDB (2015)
Major Application agriculture
environmental
InChI 1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)
InChIKey UZCGKGPEKUCDTF-UHFFFAOYSA-N
SMILES [O-][N+](=O)c1cc(c(Cl)c(c1Nc2ncc(cc2Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F
LogP 3.560
CAS DataBase Reference 79622-59-6(CAS DataBase Reference)
FDA UNII 0P91PCK33Q
Pesticides Freedom of Information Act (FOIA) Fluazinam
EPA Substance Registry System Fluazinam (79622-59-6)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)Health Hazard (GHS08)Environment (GHS09)
GHS05,GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H317-H318-H332-H361d-H410
Precautionary statements  P273-P280-P302+P352-P304+P340+P312-P305+P351+P338-P308+P313
PPE Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Hazard Codes  T;N,N,T,Xn,F
Risk Statements  23-41-43-50/53-36-20/21/22-11-38-20-63
Safety Statements  26-36/37/39-45-60-61-36/37-16-63-57-56-38-28-27-24/25-20/21-13
RIDADR  UN 2811
WGK Germany  3
RTECS  UR8085000
HazardClass  6.1
PackingGroup  II
HS Code  29333990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Inhalation
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Repr. 2
Skin Sens. 1
Hazardous Substances Data 79622-59-6(Hazardous Substances Data)
NFPA 704
0
3 0

Fluazinam price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34095 Fluazinam PESTANAL , analytical standard 79622-59-6 100mg $146 2026-04-30 Buy
TCI Chemical F0869 Fluazinam >98.0%(HPLC)(T) 79622-59-6 1g $140 2026-04-30 Buy
Cayman Chemical 36221 Fluazinam ≥95% 79622-59-6 500mg $54 2026-04-30 Buy
Cayman Chemical 36221 Fluazinam ≥95% 79622-59-6 1g $86 2026-04-30 Buy
Cayman Chemical 36221 Fluazinam ≥95% 79622-59-6 5g $203 2026-04-30 Buy
Product number Packaging Price Buy
34095 100mg $146 Buy
F0869 1g $140 Buy
36221 500mg $54 Buy
36221 1g $86 Buy
36221 5g $203 Buy

Fluazinam Chemical Properties,Uses,Production

Description

Fluazinam is a protective broad-spectrum contact fungicide registered for agricultural use to control various soil-borne fungal pathogens on a variety of crops, such as peanuts, potatoes, beans, etc. It can be applied as a foliar spray or soil treatment, which is effective against a number of diseases caused by pathogenic fungi such as gray mold, downy mildew, melanose, scab, alternaria blotch, clubroot, sclerotinia blight, white root rot, violet root rot. Besides, it shows acaricidal property, which can fight against mites in citrus.
However, as a protective agent, fluazinam is neither systemic or curative, which functions by inhibiting spore germination and spore growth, and also the development of infection structures, thereby giving it protective action with a good residual effect. The anti-fungal property of fluazinam acts by disrupting the energy production of the fungus at multiple sites and therefore preventing resistance.

uses

Fluazinam is a pyridinamine fungicide that can control blight caused by Phytophthora infestans in potatoes, beans and other crops (e.g., bushberries, edible-podded beans and cruciferous vegetables such as cabbage and broccoli). Fluazinam has strong persistence of effect against blight and can suppress secondary infection in the field through inhibition of sporulation. Fluazinam has been widely used in the U.S. since the 1990s. Fluazinam is not registered for use in California. Exposure in California would occur mainly through crops imported from other states.

Mode of Action

Fluazinam has a multi-site mode of action that disrupts energy production in fungi. Fluazinam has great protective activity, and while it has limited curative or systemic activity, it possesses very good residual effect and rain fastness.
FRAC code: 29

Toxicology & Ecotoxicology

Rat LD50 (oral) :4,500 mg/kg (m), 4,100 mg/kg (f)
Rat LD50 (dermal) :> 2,000 mg/kg bw (m/f)
Rat LC50 (inhalation) :> 1.1 mg/L (m/f)
Skin irritation :mild irritant (rabbit)
Eye irritation :irritant (rabbit)
Skin sensitization :sensitizer (guinea pig)
Avian LD50 (acute oral) :> 4,190 mg/kg (mallard duck, m/f)
Avian LD50 (acute oral) :> 1,782 mg/kg (quail, m/f)
Fish LC50 :0.11 mg/L (rainbow trout, 96h)
Bee LD50 (oral) :> 100 μg/bee
Bee LD50 (contact) :> 100 μg/bee
Daphnia magna EC50 :0.19 mg/L (48 h)

Environmental Fate

Soil
Half-life- Aerobic = 132 days
Adsorption - Low mobility with Koc values ranged from 1705-2316
Persistence- Total fluazinam residues (fluazinam and its transformation products) are persistent in most environments and are likely to reach aquatic media through runoff. Fluazinam has the potential to bioaccumulate in fish.
Water
Half-life via hydrolysis - Stable at pH 5; 42 days at pH 7; and 6 days at pH 9
Surface water - Fluazinam and its transformation products are moderately persistent and may present concerns for transport to surface water by spray drift or runoff (especially in soils with low organic content)
Groundwater - Fluazinam should not leach substantially to groundwater.
Air
Volatilization- Fluazinam has a low vapor pressure 1.73 x 10-7 mm Hg and is not likely to substantially volatilize.
Degradates
Fluazinam may photolyze relatively rapidly in water (2.5 days) to form a tricyclic compound (G-504). Degradates were included in the drinking water risk assessment. The total fluazinam residues are persistent in most environments and are likely to reach aquatic media as a totality through runoff. The total residues may reach adjacent water bodies via runoff events and may be persistent.
Label use requirements are designed to mitigate related risk concerns

References

https://en.wikipedia.org/wiki/Fluazinam
http://www.agchemaccess.com/Fluazinam
http://www.galchimia.com/chemical-catalog/pesticide-impurities-and-metabolites/fluazinam-standard/
http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/325.htm

Description

Fluazinam, with a LogP of 3.56, has very low solubility in water (1.7 mgL1, pH6.8, 25C) but higher solubilities in organic solvents (e.g., acetone 470 g/L, dichloromethane 330 g/L, ethanol 150 g/L, all at 20 C). The active ingredient forms light yellow crystals with an MP of 115 to 117 C and has a vp of 1.5 mPa (25 C). The compound is stable to acid, alkali, and heat (5).

Chemical Properties

yellow crystal mp 115 ~ 117°C

Uses

Fluazinam is a broad spectrum fungicide. Fluazinam is commonly used for control of Sclerotinia blight and other soilborne pathogens of peanut as well for the control of potato blight.

Uses

Fluazinam is a fungicide with a protective action but with little curative or systemic activity. It is used to control grey mould and downy mildew on vines, apple scab, southern blight and white mould on peanuts and Phytophthora infestans and tuber blight on potatoes. It is also used against clubroot on crucifers, rhizomania on sugar beet and mites in apples.

Definition

ChEBI: Fluazinam is a member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens. It has a role as an apoptosis inducer, an allergen, a xenobiotic, an environmental contaminant and an antifungal agrochemical. It is a C-nitro compound, a chloropyridine, an aminopyridine, a secondary amino compound, a member of monochlorobenzenes and a member of (trifluoromethyl)benzenes.

General Description

Fluazinam is a 2,6-dinitroaniline protectant fungicide, which belongs to the pyridinamine group. It can mostly find applications in agriculture.

Hazard

Moderately toxic by ingestion and inhalation. A reproductive hazard.

Agricultural Uses

Fungicide: Used to control Sclerotinia blight on peanuts and late blight and white mold on potatoes.

Trade name

FLUAZINAM 50 WP®; FROWNCIDE®; IKF-1216®; ICIA-192®; OMEGA; PP-192®; SHIRLAN®

Contact allergens

Fluazinam is a pesticide with a broad spectrum of anti fungal activity. It caused sensitization in employees in the tulip bulb industry and in farmers. Fluazinam induced contact dermatitis in a worker in a plant where it was manufactured.

Safety Profile

Moderately toxic by ingestion and inhalation. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NOx, F-, and Cl-.

Metabolic pathway

Fluazinam may typically be applied to crops of potatoes using up to 10 applications each of 150 g ha-1. Routes of degradation involve ring hydroxylation in aerobic soils and reduction of the nitro groups in flooded soils. A large amount of unextractable residue was observed. In potatoes and rats, important reactions involve the reduction of nitro groups and the formation of conjugates. In plants, the trifluoromethyl substituents are hydrolysed to carboxylic acid groups. Most of the information presented below was taken from an evaluation of the fungicide published by the UK Pesticide Safety Directorate (PSD, 1994).

Degradation

Fluazinam is stable to acid, alkali and heat (PM). The DT50 values for hydrolysis in buffer solutions held in the dark at 22 °C were 42 and 5.6 days at pH 7 and 9, respectively. There was no appreciable hydrolysis at pH 5. The major reaction involved hydrolysis of a trifluoromethyl group to give the nicotinic acid derivative (2). The DT50 values of fluazinam in buffer solutions exposed to natural sunlight were in the range 2-3 days. Up to 11 products were separated but only the major product formed at pH 9, the nicotinic acid derivative (2), was characterised (PED, 1994).

29091-09-6
79456-26-1
79622-59-6
Synthesis of Fluazinam from 2,4-Dichloro-3,5-dinitrobenzotrifluoride and 3-Chloro-5-(trifluoromethyl)pyridin-2-amine

Fluazinam Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 277)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Junruifeng New Material Co.,Ltd.
+8613932838315 hsjkchemical@163.com CHINA 6 58
Qingdao Trust Agri Chemical Co.,Ltd
+86-008615963231493 +86-008613573296305 trustagri@hotmail.com China 299 58
Shandong Jihui Chemical Co., Ltd.
+8615053042019 sales@jihuichem.com China 34 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hubei Lidu New Material Technology Co., Ltd
+86-19307248857 +86-19307248857 19307248857@163.com China 885 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
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+86-0551-65418679 +8618949832763 info@tnjchem.com China 2988 55
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+86-0371-86658258 +8613203830695 sales@coreychem.com China 29815 58
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View Lastest Price from Fluazinam manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
fluazinam pictures 2026-06-04 fluazinam
79622-59-6
1G 98% 20TONS Hubei Lidu New Material Technology Co., Ltd
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79622-59-6
$46.00 99.98% 10g TargetMol Chemicals Inc.
Fluazinam pictures 2026-05-15 Fluazinam
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$71.00 1KG 99% 1000kg Baoji Guokang Healthchem Co., Ltd.
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  • 98%
  • Hubei Lidu New Material Technology Co., Ltd
  • Fluazinam pictures
  • Fluazinam
    79622-59-6
  • $46.00
  • 99.98%
  • TargetMol Chemicals Inc.
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  • Fluazinam
    79622-59-6
  • $71.00
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SHIRLAN FLUAZINAM ikf1216 pp192 shirlan(zeneca) shirlanflow 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluor-2,6-dinitro-p-toluidine 2-Pyridinamine, 3-chloro-N-3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl-5-(trifluoromethyl)- fluazinam (bsi,iso) FLUAZINAM SOLUTION 3-Chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluoro-2,6-dinitro-p-toluidine, 3-Chloro-N-(3-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-2-pyridylamine 3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifuor-2,6-dinitro-p-toluidine B 1216 IKI 1216 Altima(TM) 3-Chloro-N-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)pyridin-2-amine FROWNCIDE 3-chloro-n-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-2-pyridinamine 3-CHLORO-N-(3-CHLORO-2,6-DINITRO-4-TRIFLUOROMETHYLPHENYL)-5-TRIFLUOROMETHYL-2-PYRIDYLAMINE 3-CHLORO-N-(3-CHLORO-5-TRIFLUOROMETHYL-2-PYRIDYL)-ALPHA,ALPHA,ALPHA-TRIFLUORO-2,6-DINITRO-P-TOLUIDINE 3-chloro-n-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-2-pyridinamin 3-chloro-n-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-2-pyridinamin 6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-3-chloro-n-(5-chloro- asc66825 asc67178 Frowncide SC 3-Chloro-N-(5-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-2-pyridinamine Fluazinam [iso] Hsdb 7264 Fluazinam 100mg [79622-59-6] AltiMa Mapro N-(3-Chloro-5-trifluoroMethyl-2-pyridyl)-2,6-dinitro-3-chloro-4-trifluoroMethylaniline Sekoya 3-Chloro-N-(3-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-2-pyridylamine, 3-Chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluoro-2,6-dinitro-p-toluidine Fluazinam Solution, 1000ppm 3-Chloro-N-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-2-pyridina FluazinamSolution,100mg/L,5x1ml FluazinamSolution,100mg/L,1ml Fluazinam@1000 μg/mL in Methanol Fluazinam Standard Fluazinam> Fluazinam @100 μg/mL in MeOH fluridine Fluazinam Solution in Methanol Fluazinam Solution in Acetonitrile Fluazinam 100 μg/ml Acetonitrile Fluazinam in Methanol Fluazinam in Acetonitrile Fluazinam, 10 mM in DMSO Fluazinam 97% min TECH Fluazinam 10 μg/mL in Cyclohexane 3-Chloro-N-(3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-pyridin-2-ylamine 50%Fluazinam 70%Fluazinam 3-Chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-α,α,α-trifluoro-2,6-dinitro-p-toluidine fluaziname 79622-59-6