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Ethyl nitroacetate

Ethyl nitroacetate structure

CAS No.: 626-35-7

Chemical Name:: Ethyl nitroacetate

Synonyms: Ethyl nitrocetate;NSC 42302;JACS-626-35-7;2-nitrobutanoate;Ethlnitroacetate;ETHYL NITROACETATE;NITRO ETHYL ACETATE;EthylNitroacetate>Ethylnitroacetate,97%;Ethyl nitroacetate,98%

CBNumber:: CB1175310

Molecular Formula:: C4H7NO4

Molecular Weight:: 133.1

MDL Number:: MFCD00007403

MOL File:: 626-35-7.mol

MSDS File:: SDS

Last updated:2026-05-27 23:11:19

Product description	Number	Pack Size	Price
Ethyl nitroacetate 97%	192333	5g	$47.3
Ethyl nitroacetate 97%	192333	25g	$183
Ethyl Nitroacetate >95.0%(GC)	N0657	5g	$51
Ethyl Nitroacetate >95.0%(GC)	N0657	25g	$148
Ethyl nitroacetate	4154-1-05	100g	$165
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Ethyl nitroacetate Properties

Boiling point	105-107 °C/25 mmHg (lit.)
Density	1.199 g/mL at 25 °C (lit.)
refractive index	n20/D 1.424(lit.)
Flash point	198 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka	pK1:5.85 (25°C)
form	Liquid
color	Clear colorless to slightly yellow
Water Solubility	Slightly soluble in water. Soluble in chloroform and ethyl acetate.
BRN	1210027
InChI	1S/C4H7NO4/c1-2-9-4(6)3-5(7)8/h2-3H2,1H3
InChIKey	FTKASJMIPSSXBP-UHFFFAOYSA-N
SMILES	CCOC(=O)C[N+]([O-])=O
CAS DataBase Reference	626-35-7(CAS DataBase Reference)
FDA UNII	7SX8B7W4RD
NIST Chemistry Reference	Acetic acid, nitro-, ethyl ester(626-35-7)
EPA Substance Registry System	Acetic acid, nitro-, ethyl ester (626-35-7)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H227-H315-H319

Precautionary statements

P280g-P305+P351+P338

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Risk Statements

Safety Statements

23-24/25-37

WGK Germany

RTECS

AJ1074000

Hazard Note

Irritant

TSCA

TSCA listed

HazardClass

IRRITANT, KEEP COLD

HS Code

29159080

Storage Class

10 - Combustible liquids

NFPA 704

	1
2		0

Ethyl nitroacetate price More Price(69)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	192333	Ethyl nitroacetate 97%	626-35-7	5g	$47.3	2026-04-30	Buy
Sigma-Aldrich	192333	Ethyl nitroacetate 97%	626-35-7	25g	$183	2026-04-30	Buy
TCI Chemical	N0657	Ethyl Nitroacetate >95.0%(GC)	626-35-7	5g	$51	2026-04-30	Buy
TCI Chemical	N0657	Ethyl Nitroacetate >95.0%(GC)	626-35-7	25g	$148	2026-04-30	Buy
SynQuest Laboratories	4154-1-05	Ethyl nitroacetate	626-35-7	100g	$165	2026-05-22	Buy

Product number	Packaging	Price	Buy
192333	5g	$47.3	Buy
192333	25g	$183	Buy
N0657	5g	$51	Buy
N0657	25g	$148	Buy
4154-1-05	100g	$165	Buy

Ethyl nitroacetate Chemical Properties,Uses,Production

Chemical Properties

clear colourless to slightly yellow liquid

Uses

Ethyl Nitroacetate is an ester of nitrocarboxylic acid used as an intermediate in the preparation of unsubstituted amino acids.

Uses

Ethyl nitroacetate has been used in the synthesis of γ-oxoacids via Michael addition reaction with α,β-unsaturated ketones, fuctionalization of C4-position on pyrimidine and C6-position on 2-deoxyguanosine to produce novel nucleosides, facile synthesis of α,α-diisobutylglycine, synthesis of DL-4,4-difluoroglutamic acid. It is also used as an intermediate in the preparation of unsubstituted amino acids.

Synthesis Reference(s)

The Journal of Organic Chemistry, 59, p. 1208, 1994 DOI: 10.1021/jo00084a047

Purification Methods

Purify the ester by repeated distillation. IR:max 1748 (CO2), 1570 and 1337 (NO2), and 800cm-1 [Haszeldine J Chem Soc 2525 1953]. The hydrazine salt crystallises from 95% EtOH or MeOH as yellow crystals m 104-105o [Ungnade & Kissinger J Org Chem 22 1661 1957, Emmons & Freeman J Am Chem Soc 77 4391 1955]. [Beilstein 2 IV 537.]

Ethyl nitroacetate synthesis

Synthesis of Ethyl nitroacetate from Ethyl cyanoformate

Ethyl nitroacetate Preparation Products And Raw materials

Raw materials

Pentanedioic acid, 2-nitro-3-oxo-, 1,5-diethyl ester TERT-BUTYL ETHYL MALONATE tert-Butanol Propanedioic acid,1-ethyl 3-methyl ester Propanoic acid, 3-[(4-methoxyphenyl)amino]-3-oxo-, ethyl ester

ALFA-NITRO ACETIC ACID Acetic acid, 2-chloro-2-nitro-, ethyl ester 3-oxo-3-(propylamino)Propanoic acid ethyl ester ethyl2-nitro-3-oxobutanoate diethyl 1,2,5-oxadiazole-3,4-dicarboxylate 2-oxide

Ethyl iodoacetate Ethyl cyanoformate ethyl glycinate Ethyl glycolate Ethyl Azidoacetate

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Preparation Products

4-HYDROXY-5-NITROPYRIMIDINE 4-BROMO-2-(TRIFLUOROMETHYL)-5-METHOXYPYRIDINE 3-FLUORO-DL-TYROSINE 2-CHLORO-2-HYDROXYIMINOACETIC ACID ETHYL ESTER

Ethyl nitroacetate Suppliers

Global( 322)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29640	60
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10403	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from Ethyl nitroacetate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-03-20	Ethyl nitroacetate 626-35-7	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2022-02-22	Ethyl nitroacetate 626-35-7	US $0.00 / KG	1KG	99.1%	100 tons	Honest Joy Holdings Limited
2021-08-12	Ethyl nitroacetate 626-35-7	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Ethyl nitroacetate
626-35-7
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Ethyl nitroacetate
626-35-7
US $0.00 / KG
99.1%
Honest Joy Holdings Limited

Ethyl nitroacetate
626-35-7
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Ethyl nitroacetate Spectrum

Ethyl nitroacetate(626-35-7)MS Ethyl nitroacetate(626-35-7)¹HNMR Ethyl nitroacetate(626-35-7)¹³CNMR Ethyl nitroacetate(626-35-7)IR1 Ethyl nitroacetate(626-35-7)Raman

626-35-7(Ethyl nitroacetate)Related Search:

Ethyl acetate Ethylparaben ISOXADIFEN-ETHYL 2-CHLORO-2-HYDROXYIMINOACETIC ACID ETHYL ESTER Ethyl hydrazinoacetate hydrochloride

Ethyl bromoacetate Ethyl phenylacetate Ethyl cyanoacetate Ethyl propiolate Ethyl acrylate

ETHYL (METHYLTHIO)ACETATE Trinexapac-ethyl Diethyl nitromalonate Methyl vanillate Cadmium diethyldithiocarbamate

Methyl nitroacetate Ethanol Bromoacetaldehyde diethyl acetal

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Acetic Acid Nitro Ethyl Ester nitro-aceticaciethylester NITROACETIC ACID ETHYL ESTER NITRO ETHYL ACETATE ETHYL NITROACETATE Ethlnitroacetate wEthyl nitroacetate, 97% Ethylnitroacetate,97% Ethyl nitroacetate 97% 2-nitrobutanoate Ethyl nitroacetate,98% 2-Nitroacetic Acid Ethyl Ester NSC 42302 Nitroacetic acid ethyl ester, Ethyl 2-nitroethanoate Ethyl nitroacetate, 95+% JACS-626-35-7 EthylNitroacetate> Acetic acid, 2-nitro-, ethyl ester Ethyl nitrocetate 626-35-7 NO2CH2CO2C2H5 O2NCH2CO2CH2CH3 O2NCH2COOC2H5 Carbonyl Compounds C2 to C5 Building Blocks Organic Building Blocks Esters Halogenated Heterocycles ,Quinolines C2 to C5 Carbonyl Compounds Esters