ChemicalBook >> CAS DataBase List >>alpha-Methylcinnamic acid

alpha-Methylcinnamic acid

alpha-Methylcinnamic acid structure

CAS No.: 1199-77-5

Chemical Name:: alpha-Methylcinnamic acid

Synonyms: (E)-2-Methyl-3-phenylacrylic acid;A-METHYLCINNAMIC ACID;2-Methyl-3-phenylacrylic acid;2M3B;α-MethyL;α-Methylciamic acid;RARECHEM AL BM 0531;α-Methylcinmic acid;alpha-Methylcinnamic;α-Methylcinnamicacid

CBNumber:: CB1176094

Molecular Formula:: C10H10O2

Molecular Weight:: 162.19

MDL Number:: MFCD00002652

MOL File:: 1199-77-5.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:41

Request For Quotation

alpha-Methylcinnamic acid Properties

Melting point	79-81 °C(lit.)
Boiling point	288 °C
Density	1.0281 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	Sealed in dry,Room Temperature
form	Crystals or Crystalline Powder
pka	4.82±0.10(Predicted)
color	White to yellow
BRN	2042544
InChI	InChI=1S/C10H10O2/c1-8(10(11)12)7-9-5-3-2-4-6-9/h2-7H,1H3,(H,11,12)
InChIKey	XNCRUNXWPDJHGV-BQYQJAHWSA-N
SMILES	C(O)(=O)C(C)=CC1=CC=CC=C1
LogP	2.600
CAS DataBase Reference	1199-77-5(CAS DataBase Reference)
FDA UNII	52D2H37MVU
NIST Chemistry Reference	«ALPHA»-methylcinnamic acid(1199-77-5)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Safety Statements

22-24/25

WGK Germany

HS Code

29163900

NFPA 704

	1
2		0

alpha-Methylcinnamic acid price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M35606	α-Methylcinnamic acid 99%	1199-77-5	25g	$155	2025-07-31	Buy
Sigma-Aldrich	M35606	α-Methylcinnamic acid 99%	1199-77-5	100g	$305	2023-01-07	Buy
TCI Chemical	M1336	α-Methylcinnamic Acid >98.0%(GC)(T)	1199-77-5	5g	$29	2025-07-31	Buy
TCI Chemical	M1336	α-Methylcinnamic Acid >98.0%(GC)(T)	1199-77-5	25g	$78	2025-07-31	Buy
TRC	B495030	α-Methylcinnamic acid	1199-77-5	1g	$55	2021-12-16	Buy

Product number	Packaging	Price	Buy
M35606	25g	$155	Buy
M35606	100g	$305	Buy
M1336	5g	$29	Buy
M1336	25g	$78	Buy
B495030	1g	$55	Buy

alpha-Methylcinnamic acid Chemical Properties,Uses,Production

Chemical Properties

WHITE TO YELLOWISH CRYSTALS OR CRYSTALLINE POWDER

Uses

Alpha-methylcinnamic acid

Synthesis Reference(s)

Journal of the American Chemical Society, 94, p. 2520, 1972 DOI: 10.1021/ja00762a060
Synthetic Communications, 19, p. 71, 1989 DOI: 10.1080/00397918908050954

Synthesis

100-52-7

123-62-6

1199-77-5

General procedure: Propionic anhydride (300 mmol, 1.6 eq.) was slowly added to a reaction vial containing potassium carbonate (224 mmol, 1.2 eq.) at 0 °C. After stirring for 5 min, benzaldehyde (186 mmol, 1.0 eq.) was added dropwise to the mixture. The reaction mixture was heated to reflux and maintained for 12 hours. Upon completion of the reaction, the mixture was cooled to room temperature using an ice bath, followed by addition of water (appropriate amount) and solid Na2CO3 (30 g) to the reaction mixture. The resulting yellow precipitate was collected by filtration and the filtrate was acidified to pH 6.0 with concentrated HCl to precipitate a solid product of 2-methyl-3-phenylpropenoic acid.

References

[1] Medicinal Chemistry Research, 2004, vol. 13, # 8-9, p. 660 - 676
[2] European Journal of Medicinal Chemistry, 2013, vol. 62, p. 632 - 648
[3] American Chemical Journal, 1906, vol. 36, p. 533
[4] Journal of the Chemical Society, 1877, vol. 31, p. 409
[5] Journal of the Chemical Society, 1878, vol. 33, p. 215

alpha-Methylcinnamic acid synthesis

Synthesis of alpha-Methylcinnamic acid from Iodobenzene and Methacrylic acid

alpha-Methylcinnamic acid Preparation Products And Raw materials

Raw materials

Benzaldehyde Iodobenzene Bromobenzene Methacrylic acid Propionic anhydride

Preparation Products

BMK methyl glycidate

alpha-Methylcinnamic acid Suppliers

Global( 271)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8617732866630	abby@chuanghaibio.com	China	8773	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	sales@hbmojin.com	China	12285	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5251	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20189	58
Hebei Zhuanglai Chemical Trading Co Ltd	+86-16264648883	niki@zlchemi.com	China	7245	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

View Lastest Price from alpha-Methylcinnamic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-22	Alpha-Methylcinnamic acid 1199-77-5	US $0.00 / G	50G	98%min	30kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-08-21	alpha-Methylcinnamic acid 1199-77-5	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd
2025-06-24	alpha-Methylcinnamic acid 1199-77-5	US $1.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd

Alpha-Methylcinnamic acid
1199-77-5
US $0.00 / G
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

alpha-Methylcinnamic acid
1199-77-5
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

alpha-Methylcinnamic acid
1199-77-5
US $1.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

alpha-Methylcinnamic acid Spectrum

alpha-Methylcinnamic acid(1199-77-5)MS alpha-Methylcinnamic acid(1199-77-5)¹HNMR alpha-Methylcinnamic acid(1199-77-5)¹³CNMR alpha-Methylcinnamic acid(1199-77-5)IR1 alpha-Methylcinnamic acid(1199-77-5)IR2 alpha-Methylcinnamic acid(1199-77-5)Raman

1199-77-5(alpha-Methylcinnamic acid)Related Search:

ALPHA-CYANOCINNAMIC ACID ETHYL ESTER Coumarin-3-carboxylic acid 3-CARBETHOXYUMBELIFERONE DIETHYL BENZYLIDENEMALONATE 2,3-DIPHENYLMALEIC ANHYDRIDE

alpha-Phenylcinnamic acid ALPHA-CYANOCINNAMIC ACID Ethyl 2-cyano-3,3-diphenylacrylate ETHYL COUMARIN-3-CARBOXYLATE alpha-Methylcinnamic acid

AFLATOXIN G1 ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Cinnamic acid trans-Cinnamic acid 3-CARBOXYUMBELLIFERYL ACETATE

ALPHA-CYANO-3-HYDROXYCINNAMIC ACID ETHYL 2-CYANO-3-(4-METHOXYPHENYL)ACRYLATE ETHYL 2-CYANO-3-(4-NITROPHENYL)PROP-2-ENOATE

1of4

2-Methyl-3-phenyl-2-propenoic acid alpha-Methylcinnamic acid,99% α-Methylciamic acid 2M3B (E)-2-Methyl-3-phenylacrylic acid alpha-Methylcinnamic acid 99% (2E)-2-methyl-3-phenylacrylic acid RARECHEM AL BM 0531 (2E)-2-Methyl-3-phenyl-2-propenoic acid 2-Propenoic acid, 2-methyl-3-phenyl- alpha-Methylcinnamic Cinnamic acid, alpha-methyl- α-Methylcinnamicacid 2-Methyl-3-phenylacrylic acid ALPHA-METHYLCINNAMIC ACID A-METHYLCINNAMIC ACID à-methylcinnamic acid 2-METHYL-3-PHENYLPROPENOICACID ɑ-Methylcinnamic acid, 99% α-MethylcinnamicAcid> Epalrestat Impurity 11 (alpha-Methylcinnamic acid) α-MethyL α-Methylcinnamic acid ALPHA-METHYLCINNAMIC ACID 1199-77-5 Epalrestat Impurity 36 Lenacapavir Impurity 4 Epalrestat 2-methyl-3-phenyl-2-acrylic acid α-Methylcinnamic acid, CAS 1199-77-5 α-Methylcinmic acid 1199-77-5 1197-77-5 Organic Building Blocks Building Blocks C10 Carbonyl Compounds Carboxylic Acids Building Blocks Carbonyl Compounds Carboxylic Acids Chemical Synthesis Organic Building Blocks Carboxylic Acids C10 Carbonyl Compounds Cinnamic acid 1199-77-5 11