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Homatropine Hydrobromide

Homatropine Hydrobromide structure

CAS No.: 51-56-9

Chemical Name:: Homatropine Hydrobromide

Synonyms: DL-Hydrobromide;r,hbr,endo-(+-);Homatropine HBr;HoMatropineHBrUSP;Isopto Homatropine;Homatropinhydrobromid;endo-(+/-)-hydrobromid;(+-)-homatropinebromide;HOMATROPINE HYDROBROMIDE;HomatropineHydrobromideGr

CBNumber:: CB1185212

Molecular Formula:: C16H21NO3.BrH

Molecular Weight:: 356.25

MDL Number:: MFCD00012676

MOL File:: 51-56-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:11:35

Product description	Number	Pack Size	Price
Homatropine Hydrobromide pharmaceutical secondary standard, certified reference material	PHR3182	500MG	$233
Homatropin hydrobromide phyproof? Reference Substance	PHL84120	50MG	$247
Homatropine hydrobromide European Pharmacopoeia (EP) Reference Standard	H0800000	100 mg	$127
Homatropine hydrobromide British Pharmacopoeia (BP) Reference Standard	BP185	100MG	$242
Homatropine hydrobromide United States Pharmacopeia (USP) Reference Standard	1310008	200mg	$417
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Homatropine Hydrobromide Properties

Melting point	214-217 °C
storage temp.	2-8°C
solubility	Freely soluble in water, sparingly soluble in alcohol.
form	Solid
color	White to Off-White
Water Solubility	soluble
Merck	14,4730
CAS DataBase Reference	51-56-9(CAS DataBase Reference)
FDA UNII	BEW7469QZ0
EPA Substance Registry System	Homatropine hydrobromide (51-56-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H332-H312

Precautionary statements

P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501

Hazard Codes

Risk Statements

23/24/25

Safety Statements

45-24/25-22

RIDADR

1544

WGK Germany

RTECS

YM5602000

TSCA

TSCA listed

HazardClass

6.1

PackingGroup

III

HS Code

29399900

NFPA 704

	0
3		0

Homatropine Hydrobromide price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR3182	Homatropine Hydrobromide pharmaceutical secondary standard, certified reference material	51-56-9	500MG	$233	2026-04-30	Buy
Sigma-Aldrich	PHL84120	Homatropin hydrobromide phyproof? Reference Substance	51-56-9	50MG	$247	2026-04-30	Buy
Sigma-Aldrich	H0800000	Homatropine hydrobromide European Pharmacopoeia (EP) Reference Standard	51-56-9	100 mg	$127	2026-04-30	Buy
Sigma-Aldrich	BP185	Homatropine hydrobromide British Pharmacopoeia (BP) Reference Standard	51-56-9	100MG	$242	2026-04-30	Buy
Sigma-Aldrich	1310008	Homatropine hydrobromide United States Pharmacopeia (USP) Reference Standard	51-56-9	200mg	$417	2026-04-30	Buy

Product number	Packaging	Price	Buy
PHR3182	500MG	$233	Buy
PHL84120	50MG	$247	Buy
H0800000	100 mg	$127	Buy
BP185	100MG	$242	Buy
1310008	200mg	$417	Buy

Homatropine Hydrobromide Chemical Properties,Uses,Production

Description

Homatropine is an anticholinergic agent. It reduces acetylcholine-induced contractions of isolated goat detrusor muscle strips when used at a concentration of 5 μM. Homatropine (1 μM) inhibits acetylcholine- or methacholine-induced contraction of isolated rat anococcygeus muscle. It inhibits serotonin- or thrombin-induced platelet aggregation in isolated sheep platelet-rich plasma (IC₅₀s = 4.3 and 100 μM, respectively). Topical ophthalmic administration of homatropine induces partial mydriasis in Angora goats.

Chemical Properties

white crystals or crystalline powder

Uses

Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.

Uses

anticholinergic (opthalmic)

brand name

Isopto Homatropine (Alcon) .

General Description

Homatropine hydrobromide,1 H,5 H-tropan-3 -ol mandelate (ester) hydrobromide(Homatrocel), occurs as white crystals or as awhite, crystalline powder that is affected by light. It is solublein water (1:6) and alcohol (1:40), less soluble in chloroform(1:420), and insoluble in ether.
Solutions are incompatible with alkaline substances,which precipitate the free base, and with the commonreagents that precipitate alkaloids. As with atropine, solutionsare sterilized best by filtration through a bacteriologicalfilter.

Clinical Use

Homatropine hydrobromide is used topically to paralyzethe ciliary structure of the eye (cycloplegia) and to effectmydriasis. It behaves very much like atropine but is weakerand less toxic. In the eye, it acts more rapidly but less persistentlythan atropine. Dilation of the pupil takes place inabout 15 to 20 minutes, and the action subsides in about24 hours. By using a miotic, such as physostigmine, it ispossible to restore the pupil to normality in a few hours.

References

[1] N. GEORGE. Inhibitory effect of anticholinergics on the contraction of isolated caprine urinary bladder detrusor muscle[J]. Autonomic and Autacoid Pharmacology, 2010, 30 3: 173-177. DOI: 10.1111/j.1474-8673.2009.00447.x
[2] DOGGRELL S A. Effect of antimuscarinic agents on the contractile responses to cholinomimetics in the rat anococcygeus muscle.[J]. British Journal of Pharmacology, 1981, 73 4: 829-835. DOI: 10.1111/j.1476-5381.1981.tb08735.x
[3] F MICHAL F P. Inhibition of serotonin-induced platelet aggregation in relation to thrombus production.[J]. Journal of Pharmacology and Experimental Therapeutics, 1969, 166 2: 276-284.
[4] N C WHELAN I L F Castillo Alcala. Efficacy of tropicamide, homatropine, cyclopentolate, atropine and hyoscine as mydriatics in Angora goats.[J]. New Zealand veterinary journal, 2011, 59 6: 328-331. DOI: 10.1080/00480169.2011.609476

Homatropine Hydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

Homatropine Hydrobromide Suppliers

Global( 241)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29766	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10399	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63645	58
CONIER CHEM AND PHARMA LIMITED		sales@conier.com	China	49906	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17339	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +86-189 4982 3763	sales@tnjchem.com	China	34526	58
ANHUI WITOP BIOTECH CO., LTD	+8618071025641	eric@witopchemical.com	China	23506	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1059@dideu.com	China	29096	58
AFINE CHEMICALS LIMITED	+86-571-85134551 +86-18958018566	info@afinechem.com	China	15058	58
Alfa Chemistry	--	info@alfa-chemistry.com	United States	2343	58

Supplier	Advantage
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58
Dideu Industries Group Limited	58
AFINE CHEMICALS LIMITED	58
Alfa Chemistry	58

View Lastest Price from Homatropine Hydrobromide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	Homatropine Hydrobromide USP/EP/BP 51-56-9	$1.10	1g	99.9%	100 Tons min	Dideu Industries Group Limited
2022-02-23	Homatropine Hydrobromide 51-56-9	$8.80-9.90	10g	99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets，Customiz	1000kgs	Shanghai Biolang Biotechnology Co., Ltd.
2019-07-06	alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide 51-56-9	$2.00	1kg	99%	100kg	Career Henan Chemical Co

Homatropine Hydrobromide USP/EP/BP
51-56-9
$1.10
99.9%
Dideu Industries Group Limited

Homatropine Hydrobromide
51-56-9
$8.80-9.90
99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets，Customiz
Shanghai Biolang Biotechnology Co., Ltd.

alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
51-56-9
$2.00
99%
Career Henan Chemical Co

Homatropine Hydrobromide Spectrum

Homatropine Hydrobromide(51-56-9)¹HNMR Homatropine Hydrobromide(51-56-9)¹³CNMR Homatropine Hydrobromide(51-56-9)IR1 Homatropine Hydrobromide(51-56-9)IR2

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alpha-hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide MANDELYTROPINE HYDROBROMIDE (+/-)-HOMATROPINE HYDROBROMIDE HOMATROPINE HYDROBROMIDE DL-HOMATROPINE HYDROBROMIDE (+-)-homatropinebromide 1-alpha-h,5-alpha-h-tropan-3-alpha-ol,mandelate(ester),hydrobromide Tropine mandelate hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide 1aH,5aH-Tropan-3a-ol, mandelate (ester), hydrobromide Benzeneacetic acid, a-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (RS)-3alpha(1alphaH,5alphaH)-Tropanylmandelat hydrobromide HOMATROPINE HYDROBROMIDE(RG) HoMatropineHBrUSP endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobroMide 1αH,5αH-Tropan-3α-ol Mandelate (Ester) HydrobroMide rac HoMatropine HydrobroMide α-Hydroxybenzeneacetic Acid (3-Endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester, HydrobroMide DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide Tropine mandelate hydrobromide (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobroMide Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1) DL-Hydrobromide 8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate hydrobromide alpha-hydroxy-benzeneaceticaci8-methyl-8-azabicyclo(3.2.1)oct-3-yleste benzeneaceticacid,alpha-hydroxy-,8-methyl-8-azabicyclo[3.2.1]oct-3-ylester, endo-(+/-)-hydrobromid r,hbr,endo-(+-) HOMATROPINEHYDROBROMIDE,CRYSTAL,USP 1αH,5αH-Tropan-3α-ol, mandelate (ester), hydrobromide (8CI) Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, endo- Isopto Homatropine Mandelic acid tropine ester hydrobromide Homatropinhydrobromid Homatropine HBr HomatropineHydrobromideGr DL-Homatropine hydrobromide, 98.5-100.5% Homatropine hydrobromide CRS Hyoscine hydrobromide CRS Homatropine Methylbromide EP Impurity B Homatropine Hydrobromide USP/EP/BP dextro,laevo-homatropine hydrobromide Homatropine Bromide (Homatropine hydrobromide) Homatropine hydrobromide, GR 99% Homatropine HydrobromideQ: What is Homatropine Hydrobromide Q: What is the CAS Number of Homatropine Hydrobromide Q: What is the storage condition of Homatropine Hydrobromide Q: What are the applications of Homatropine Hydrobromide Homatropine Hydrobromide (1310008) Atropine Impurity 6 HBr (Homatropine HBr) DL-Homatropine hydrobromide -100gms Atropine Impurity 14 HBr (Homatropine HBr) Hydrobromic acid post atropine/post atropine hydrobromide DL-Homatropine hydrobromide EP 51-56-9 C16H21NO3HBr C16H20NO3 C16H22NO3Br Alkaloids Tropane Alkaloids Aromatics