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ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE structure

CAS No.: 124755-24-4

Chemical Name:: ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE

Synonyms: ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE;Ethyl 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]acetate;Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate;Ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate 97%;Di(3,3,3-trifluoroethyl)(ethoxycarbonylmethyl)phosphonate;[Bis-(2,2,2-trifluoro-ethoxy)-phosphoryl]-acetic acid ethyl ester;[BIS-(2,2,2-TRIFLUORO-ETHOXY)-PHOSPHORYL]-ACETIC ACID METHYL ESTER;Acetic acid, 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]-, ethyl ester

CBNumber:: CB1206274

Molecular Formula:: C8H11F6O5P

Molecular Weight:: 332.13

MDL Number:: MFCD01318337

MOL File:: 124755-24-4.mol

Last updated:2026-01-13 11:13:45

Product description	Number	Pack Size	Price
Ethyl[Bis(2,2,2-trifluoroethoxy)phosphinyl]acetate	E677510	1g	$100
Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	P000231421	5g	$102
Ethyl2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate	Z4021	5g	$237
Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	P000231421	25g	$403
Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	P000231421	10g	$170

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ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Properties

Boiling point	249-250 °C(lit.)
Density	1.403 g/mL at 25 °C(lit.)
refractive index	n20/D 1.3730(lit.)
Flash point	>230 °F
storage temp.	2-8°C, stored under nitrogen
Appearance	Colorless to light yellow Liquid
InChI	InChI=1S/C8H11F6O5P/c1-2-17-6(15)3-20(16,18-4-7(9,10)11)19-5-8(12,13)14/h2-5H2,1H3
InChIKey	HBYHPBCAZBLFTD-UHFFFAOYSA-N
SMILES	C(OCC)(=O)CP(OCC(F)(F)F)(OCC(F)(F)F)=O
UNSPSC Code	12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
target organs	Respiratory system
PPE	Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
Storage Class	10 - Combustible liquids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	E677510	Ethyl[Bis(2,2,2-trifluoroethoxy)phosphinyl]acetate	124755-24-4	1g	$100	2021-12-16	Buy
Ark Pharm	P000231421	Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	124755-24-4	5g	$102	2021-12-16	Buy
AK Scientific	Z4021	Ethyl2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate	124755-24-4	5g	$237	2021-12-16	Buy
Ark Pharm	P000231421	Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	124755-24-4	25g	$403	2021-12-16	Buy
Ark Pharm	P000231421	Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 97%	124755-24-4	10g	$170	2021-12-16	Buy

Product number	Packaging	Price	Buy
E677510	1g	$100	Buy
P000231421	5g	$102	Buy
Z4021	5g	$237	Buy
P000231421	25g	$403	Buy
P000231421	10g	$170	Buy

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Chemical Properties,Uses,Production

Uses

Ethyl [Bis(2,2,2-trifluoroethoxy)phosphinyl]acetate is a reagent used in the preparation of spiroketal EBC-23; an anticancer agent, scytonemin A; a novel calcium antagonist and other useful organic compounds.

Synthesis

To stirred solution of 18-crown-6 (4.40 g, 16.65 mmol), THF (20 mL), and bis (2,2,2-trifluoroethyl) phosphite (1) (0.55 mL, 3.75 mmol), KHMDS (8.0 mL, 4.00 mmol, 0.5 M in toluene) was added via syringe in a dropwise manner at -78 oC. Ethyl chloroacetate (0.35 mL, 3.30 mmol) was added to the flask after 15 min. The reaction flask was allowed to warm to room temperature and stir for 4 hr. After standard workup procedure, the crude product was then purified by flash column chromatography (2:1-1:1 hexanes:EtOAc, Rf = 0.25 in 2:1 hexanes:EtOAc) yielding Ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate (808 mg, 2.43 mmol, 73.4%) as a yellow syrup.

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE synthesis

Synthesis of ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE from BIS(2 2 2-TRIFLUOROETHYL)METHYLPHOSPHON&

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Preparation Products And Raw materials

Raw materials

Acetic acid, (dichlorophosphinyl)-, ethyl ester BIS(2 2 2-TRIFLUOROETHYL)METHYLPHOSPHON& BIS(2,2,2-TRIFLUOROETHYL) PHOSPHITE Ethyl chloroformate Ethyl bromoacetate

2,2,2-Trifluoroethanol

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Preparation Products

ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Suppliers

Global( 76)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-18192627656	1059@dideu.com	China	3589	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4017	58
Henan Alfa Chemical Co., Ltd	+8615838112936	sale03@alfachem.cn	China	12830	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	24597	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43333	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33325	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hubei xin bonus chemical co. LTD	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	58
Henan Alfa Chemical Co., Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58
HANGZHOU LEAP CHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58

View Lastest Price from ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2025-12-12	Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate 124755-24-4	US $1.00-0.00 / KG	1KG	99%	50 tons	Shaanxi Dideu Medichem Co. Ltd

Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate
124755-24-4
US $1.00-0.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

124755-24-4(ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE)Related Search:

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BIS(2,2,2-TRIFLUOROETHYL) (METHOXYCARBONYLMETHYL)PHOSPHONATE

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Ethyl 2-(bis(2,2,2-trifluoroethoxy)phosphoryl)acetate [BIS-(2,2,2-TRIFLUORO-ETHOXY)-PHOSPHORYL]-ACETIC ACID METHYL ESTER ETHYL [BIS(2,2,2-TRIFLUOROETHOXY)PHOSPHINYL]ACETATE Ethyl [bis(2,2,2-trifluoroethoxy)phosphinyl]acetate 97% Di(3,3,3-trifluoroethyl)(ethoxycarbonylmethyl)phosphonate [Bis-(2,2,2-trifluoro-ethoxy)-phosphoryl]-acetic acid ethyl ester Acetic acid, 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]-, ethyl ester Ethyl 2-[bis(2,2,2-trifluoroethoxy)phosphinyl]acetate 124755-24-4 C8H11F6O5P Organic Building Blocks Building Blocks Phosphonates/Phosphinates Phosphorus Compounds Organic Building Blocks Phosphonates/Phosphinates Phosphorus Compounds