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ChemicalBook >> CAS DataBase List >>4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Structure
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride structure
CAS No.
300827-87-6
Chemical Name:
4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
Synonyms
D2069;Desvenlafaxine HCl;Venlafaxine Impurity 16;Desvenlafaxine hydrochloride;4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride
CBNumber:
CB12101937
Molecular Formula:
C16H25NO2HCl
Molecular Weight:
0
MDL Number:
MFCD11045287
MOL File:
300827-87-6.mol
Last updated:2025-01-27 09:38:02
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4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Properties

Melting point >75°C (dec.)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
form powder
color white to off-white
Stability Hygroscopic
FDA UNII 3TP4E4F972
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
WGK Germany  3

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D2069 Desvenlafaxine hydrochloride ≥98% (HPLC), powder 300827-87-6 10mg $233 2024-03-01 Buy
Sigma-Aldrich D2069 Desvenlafaxine hydrochloride ≥98% (HPLC), powder 300827-87-6 50mg $711 2024-03-01 Buy
TRC D297928 Desvenlafaxine hydrochloride 300827-87-6 50mg $525 2021-12-16 Buy
American Custom Chemicals Corporation API0008432 DESVENLAFAXINE HYDROCHLORIDE 95.00% 300827-87-6 10MG $713.71 2021-12-16 Buy
American Custom Chemicals Corporation API0008432 DESVENLAFAXINE HYDROCHLORIDE 95.00% 300827-87-6 50MG $1220.03 2021-12-16 Buy
Product number Packaging Price Buy
D2069 10mg $233 Buy
D2069 50mg $711 Buy
D297928 50mg $525 Buy
API0008432 10MG $713.71 Buy
API0008432 50MG $1220.03 Buy

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Chemical Properties,Uses,Production

Uses

Desvenlafaxine Hydrochloride is a major active metabolite of venlafaxine (V120000), which is a slective serotonin noradrenaline reuptake inhibitor and used as an antidepressant.

Uses

Desvenlafaxine hydrochloride has been used to evaluate if its occurrence in drinking water at environmental concentrations could induce neuronal gene expression.

Biochem/physiol Actions

Desvenlafaxine hydrochloride is a dual SERT/NET reuptake inhibitor. It is a major active metabolite of venlafaxine (#542); brain penetrant; Ki = 40 nM and 122 nM for hSERT and hNET, respectively (weak binding at the hDAT). Inhibition of [3H]5-HT or [3H]NE uptake for the hSERT or hNET produced IC50 values of 47 and 531 nM.

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride synthesis

99300-78-4
300827-87-6
Synthesis of 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride from Venlafaxine hydrochloride

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

O-Desmethylvenlafaxine

4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Suppliers

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32361 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
SynAsst Chemical. 021-60343070 China 12740 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Shenzhen SUNGENING Bio-Medical Co., Ltd. 0755-28967200 13631290199 wxf@sungening.com China 9583 60
Guangzhou Dreampharm Biotechnology Co., Ltd. 020-36607679 17825480238 3008233746@qq.com China 9934 12
Supplier Advantage
Standardpharm Co. Ltd. 		58
Alchem Pharmtech,Inc. 		58
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
SynAsst Chemical. 55
Sigma-Aldrich 80
Alfa Chemistry 60
Shanghai EFE Biological Technology Co., Ltd. 58
Shenzhen SUNGENING Bio-Medical Co., Ltd. 60
Guangzhou Dreampharm Biotechnology Co., Ltd. 12

300827-87-6(4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride)Related Search:

1-[2-(DiMethyloxidoaMino)-1-(4-Methoxyphenyl)ethyl]cyclohexanol rac N-DesMethyl-N-(4-Methoxyphenethyl) Venlafaxine 2-(1-HydroxyCyclohexyl)-2-(4-MethoxyPhenyl)Acetonitrile 1-[2-Amino-1-(4-methoxyphenyl)-ethyl]-cyclohexanol hydrochloride ethyl 3-(dimethylamino)-2-(4-methoxyphenyl)propanoate hydrochloride
Venlafaxine N-Dimer (5RS)-5-(4-Methoxyphenyl)-3-Methyl-1-oxa-3-azaspiro-[5.5]undecane Hydrochloride Venlafaxine Related Compound A (10 mg) (1-(1-(4-Methoxyphenyl)-2-(methylamino)ethyl)cyclohexanol hydrochloride) D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine (2RS)-2-(Cyclohex-1-enyl)-2-(4-Methoxyphenyl)-N,N-diMethylethanaMine Hydrochloride
(2RS)-2-Cyclohexyl-2-(4-Methoxyphenyl)-N,NdiMethylethanaMineHydrochloride Venlafaxine hydrochloride

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4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]-phenol hydrochloride Desvenlafaxine hydrochloride D2069 Venlafaxine Impurity 16 Desvenlafaxine HCl 300827-87-6