2-Bromo-6-methoxypyridine
- CAS No.
- 40473-07-2
- Chemical Name:
- 2-Bromo-6-methoxypyridine
- Synonyms
- 6-BroMo-2-Methoxypyridine;NSC 84173;2-BROMO-6-METHOXYPYRIDINE;2-Methoxy-6-broMopyridine;2-BROMO-6-METHOXYPYRIMIDINE;Pyridine, 2-broMo-6-Methoxy-;2-Bromo-6-(methyloxy)pyridine;2-Bromo-6-methoxypyridine >2-BROMO-6-METHOXY-PYRIDINE 98%;2-Bromo-6-methoxypyridine ,98%
- CBNumber:
- CB1210598
- Molecular Formula:
- C6H6BrNO
- Molecular Weight:
- 188.02
- MDL Number:
- MFCD00088345
- MOL File:
- 40473-07-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 2-Bromo-6-methoxypyridine 97% | 520535 | 5ml | $101 |
| 2-Bromo-6-methoxypyridine >97.0%(GC) | B3260 | 5g | $32 |
| 2-Bromo-6-methoxypyridine >97.0%(GC) | B3260 | 25g | $127 |
| 2-Bromo-6-methoxypyridine Asreported | 266380 | 10g | $333 |
| 2-Bromo-6-methoxypyridine Asreported | 266380 | 25g | $513 |
| More product size | |||
| Boiling point | 206 °C (lit.) |
|---|---|
| Density | 1.53 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 220 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | -1.04±0.10(Predicted) |
| form | Liquid |
| color | Clear colorless to golden |
| InChI | InChI=1S/C6H6BrNO/c1-9-6-4-2-3-5(7)8-6/h2-4H,1H3 |
| InChIKey | KMODISUYWZPVGV-UHFFFAOYSA-N |
| SMILES | C1(Br)=NC(OC)=CC=C1 |
| CAS DataBase Reference | 40473-07-2(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi,T,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Bromo-6-methoxypyridine price More Price(81)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 520535 | 2-Bromo-6-methoxypyridine 97% | 40473-07-2 | 5ml | $101 | 2026-04-30 | Buy |
| TCI Chemical | B3260 | 2-Bromo-6-methoxypyridine >97.0%(GC) | 40473-07-2 | 5g | $32 | 2026-04-30 | Buy |
| TCI Chemical | B3260 | 2-Bromo-6-methoxypyridine >97.0%(GC) | 40473-07-2 | 25g | $127 | 2026-04-30 | Buy |
| Usbiological | 266380 | 2-Bromo-6-methoxypyridine Asreported | 40473-07-2 | 10g | $333 | 2026-06-03 | Buy |
| Usbiological | 266380 | 2-Bromo-6-methoxypyridine Asreported | 40473-07-2 | 25g | $513 | 2026-06-03 | Buy |
2-Bromo-6-methoxypyridine Chemical Properties,Uses,Production
Chemical Properties
Light yellow liquid
Uses
The commercial 2-Bromo-6-methoxypyridine could be used as a starting material to synthesize cyclopenta[b]pyridin-2,5-dione. The overall route consists of a first sequence of regioselective ortho lithiation and methoxycarbonylation followed by Heck vinylation, alkene reduction, cyclization, and decarboxylation[1].
Synthesis
626-05-1
124-41-4
40473-07-2
Under argon protection, sodium methanol (1.82 g) was slowly added to a solution of toluene (120 mL) containing 2,6-dibromopyridine (8.0 g), followed by continuous stirring at 120 °C for 13 hours. During the reaction, sodium methanol (0.728 g) was added supplementally and stirring was continued at the same temperature for 6 hours. Upon completion of the reaction, the mixture was naturally cooled to room temperature. The reaction mixture was transferred to a dispensing funnel and partitioned by adding water and ethyl acetate. The organic layer was separated, dried with anhydrous sodium sulfate, filtered and the solvent was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate gradient) to afford 2-bromo-6-methoxypyridine as an oil (5.64 g, 89% yield). The structure of the product was confirmed by 1H-NMR (400 MHz, CDCl3): δ 3.93 (3H, s, OCH3), 6.68 (1H, d, J = 8.0 Hz, Ar-H), 7.05 (1H, d, J = 7.2 Hz, Ar-H), 7.39-7.42 (1H, m, Ar-H).
References
[1] Robert, Nicolas , et al. "A convenient synthesis of cyclopenta[b]pyridin-2,5-dione as a non- glycosidic cardiotonic agent." ARKIVOC 2008.7(2008):92-100.
2-Bromo-6-methoxypyridine Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
View Lastest Price from 2-Bromo-6-methoxypyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 2-Bromo-6-methoxypyridine
40473-07-2
|
$9.80 | 1KG | 99% | 10 tons | Hebei Chuanghai Biotechnology Co., Ltd | |
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2025-11-18 | 2-Bromo-6-methoxypyridine
40473-07-2
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
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2025-09-25 | 2-Bromo-6-methoxypyridine
40473-07-2
|
$5.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd |
-

- 2-Bromo-6-methoxypyridine
40473-07-2
- $9.80
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 2-Bromo-6-methoxypyridine
40473-07-2
- $1.10
- 99.00%
- Dideu Industries Group Limited
-

- 2-Bromo-6-methoxypyridine
40473-07-2
- $5.00
- 98%
- Henan Fengda Chemical Co., Ltd
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