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6,7-Dimethoxy-1-tetralone

6,7-Dimethoxy-1-tetralone structure

CAS No.: 13575-75-2

Chemical Name:: 6,7-Dimethoxy-1-tetralone

Synonyms: 4-dihydro-6;7-diMethoxy-;6,7-DIMETHOXY-1-TETRALONE;6,7-dimethoxytetralin-1-one;6,7-Dimethoxy-1-tetralone 97%;6,7-DIMETHOXY-1-TETRALONE, 97%%;6,7-Dimethoxy-3,4-dihydro-2H-naphthalen-1-one;6,7-diMethoxy-3,4-dihydronaphthalen-1(2H)-one;3,4-Dihydro-6,7-dimethoxy-1(2H)-naphthalenone;1(2H)-Naphthalenone, 3,4-dihydro-6,7-dimethoxy-

CBNumber:: CB1218024

Molecular Formula:: C12H14O3

Molecular Weight:: 206.24

MDL Number:: MFCD00134100

MOL File:: 13575-75-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:42

Product description	Number	Pack Size	Price
6,7-Dimethoxy-1-tetralone 97%	273937	1g	$100
6,7-Dimethoxy-1-tetralone 97%	273937	5g	$582
6,7-Dimethoxy-3,4-dihydronaphthalen-1(2H)-one min. 95.0 %	D6363	1G	$99
6,7-Dimethoxy-1-tetralone	B429603	500mg	$130
6,7-Dimethoxy-1-tetralone	FD149587	2g	$181
More product size

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6,7-Dimethoxy-1-tetralone Properties

Melting point	98-100 °C(lit.)
Boiling point	358.3±42.0 °C(Predicted)
Density	1.140±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
form	Crystalline Powder or Crystals
color	White to off-white
CAS DataBase Reference	13575-75-2(CAS DataBase Reference)
FDA UNII	K5A3S85SQP
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Safety Statements

22-24/25

WGK Germany

NFPA 704

	1
2		0

6,7-Dimethoxy-1-tetralone price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	273937	6,7-Dimethoxy-1-tetralone 97%	13575-75-2	1g	$100	2025-07-31	Buy
Sigma-Aldrich	273937	6,7-Dimethoxy-1-tetralone 97%	13575-75-2	5g	$582	2023-06-20	Buy
TCI Chemical	D6363	6,7-Dimethoxy-3,4-dihydronaphthalen-1(2H)-one min. 95.0 %	13575-75-2	1G	$99	2025-07-31	Buy
TRC	B429603	6,7-Dimethoxy-1-tetralone	13575-75-2	500mg	$130	2021-12-16	Buy
Biosynth Carbosynth	FD149587	6,7-Dimethoxy-1-tetralone	13575-75-2	2g	$181	2021-12-16	Buy

Product number	Packaging	Price	Buy
273937	1g	$100	Buy
273937	5g	$582	Buy
D6363	1G	$99	Buy
B429603	500mg	$130	Buy
FD149587	2g	$181	Buy

6,7-Dimethoxy-1-tetralone Chemical Properties,Uses,Production

Uses

6,7-Dimethoxy-1-tetralone was used in the synthesis of 2-bromotetralones by undergoing bromination. It was also used as a precursor to quinolines with dopaminergic activity, naphthols with anti-inflammatory activity and benzophenanthridine alkaloids with antitumor activity.

Synthesis Reference(s)

Tetrahedron Letters, 24, p. 2939, 1983 DOI: 10.1016/S0040-4039(00)88063-6

General Description

6,7-Dimethoxy-1-tetralone reacts with 2-amino-4,5-dimethoxyacetophenone to form 5,6-dihydro-2,3,9,10-tetramethoxybenz[c]acridine.

Synthesis

13575-74-1

13575-75-2

General procedure for the synthesis of 6,7-dimethoxy-3,4-dihydronaphthalen-1(2H)-one from 4-(3,4-dimethoxyphenyl)butyric acid: polyphosphoric acid (210 g) was added to a solution of dichloromethane (50 mL) in which 4-(3,4-dimethoxyphenyl)butyric acid (0.19 mol, 42 g) was dissolved, and the mixture was heated for 2 hr under reflux conditions. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was slowly poured into crushed ice. The pH of the solution was adjusted to 7-8 with alkali, and the precipitate precipitated was filtered and dried to give 6,7-dimethoxy-3,4-dihydronaphthalen-1(2H)-one (36 g, 93.3% yield) as a white solid with a melting point of 94-96 °C (literature value: 96-98 °C).1H NMR (400 MHz, CDCl3): δ 7.51 (s, 1H), 6.67 (s 1H), 3.93 (s, 3H), 3.91 (s, 3H), 2.89 (t, J=6Hz, 2H), 2.60 (t, J=6.4Hz, 2H), 2.15-2.09 (m, 2H); 13C NMR (101MHz, CDCl3): δ197.10, 153.51, 147.96, 139.27 125.79, 110.22, 108.57, 55.98, 38.50, 29.44, 23.61.

References

[1] Synthetic Communications, 2009, vol. 39, # 15, p. 2664 - 2673
[2] Journal of Organic Chemistry, 1985, vol. 50, # 24, p. 4933 - 4938
[3] European Journal of Medicinal Chemistry, 2012, vol. 53, p. 52 - 63
[4] Pharmazie, 1981, vol. 36, # 2, p. 88 - 91
[5] Tetrahedron Letters, 2009, vol. 50, # 13, p. 1407 - 1410

6,7-Dimethoxy-1-tetralone synthesis

Synthesis of 6,7-Dimethoxy-1-tetralone from 4-(3,4-DIMETHOXYPHENYL)BUTYRIC ACID

6,7-Dimethoxy-1-tetralone Preparation Products And Raw materials

Raw materials

4-(3,4-DIMETHOXYPHENYL)BUTYRIC ACID Dichloromethane Polyphosphoric acid

Preparation Products

6,7-Dimethoxy-1-tetralone Suppliers

Global( 105)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29847	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10237	58
Unipharm pharmaceutical industry Co., Ltd	536-8266195 +8613953676784	lee@unipharm-sd.com	China	1202	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9911	58
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8645	58
Golden Pharma Co., Limited	+undefined18958062155	sales@zjgoldpharm.com	China	5899	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43339	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

Supplier	Advantage
career henan chemical co	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Hubei Ipure Biology Co., Ltd	58
Unipharm pharmaceutical industry Co., Ltd	58
Hefei Hirisun Pharmatech Co., Ltd	58
CR Corporation Limited	58
Golden Pharma Co., Limited	58
HANGZHOU LEAP CHEM CO., LTD.	58
Aladdin Scientific	58

View Lastest Price from 6,7-Dimethoxy-1-tetralone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-08-12	6,7-Dimethoxy-1-tetralone 13575-75-2	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-02	6,7-Dimethoxy-1-tetralone 13575-75-2	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-07-14	6,7-Dimethoxy-1-tetralone 13575-75-2	US $1.00 / KG	1KG	90%-99.9%	500kg	Career Henan Chemical Co

6,7-Dimethoxy-1-tetralone
13575-75-2
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

6,7-Dimethoxy-1-tetralone
13575-75-2
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

6,7-Dimethoxy-1-tetralone
13575-75-2
US $1.00 / KG
90%-99.9%
Career Henan Chemical Co

6,7-Dimethoxy-1-tetralone Spectrum

6,7-Dimethoxy-1-tetralone(13575-75-2)¹HNMR 6,7-Dimethoxy-1-tetralone(13575-75-2)Raman 6,7-Dimethoxy-1-tetralone(13575-75-2)IR

13575-75-2(6,7-Dimethoxy-1-tetralone)Related Search:

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6,7-DIMETHOXY-2-TETRALONE 7-Methoxy-1-tetralone 6-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALENE 5 8-DIMETHOXY-1-TETRALONE 99 6,8-Dimethoxyl-2-tetralone

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6,7-DIMETHOXY-1-TETRALONE 6,7-DIMETHOXY-1-TETRALONE, 97%% 6,7-Dimethoxy-3,4-dihydro-2H-naphthalen-1-one 6,7-dimethoxytetralin-1-one 4-dihydro-6 7-diMethoxy- 6,7-diMethoxy-3,4-dihydronaphthalen-1(2H)-one 6,7-Dimethoxy-1-tetralone 97% 1(2H)-Naphthalenone, 3,4-dihydro-6,7-dimethoxy- 3,4-Dihydro-6,7-dimethoxy-1(2H)-naphthalenone 13575-75-2 C11 to C12 Carbonyl Compounds Building Blocks Ketones Organic Building Blocks C11 to C12 Carbonyl Compounds Ketones