ChemicalBook >> CAS DataBase List >>L-MIMOSINE

L-MIMOSINE

L-MIMOSINE structure

CAS No.: 500-44-7

Chemical Name:: L-MIMOSINE

Synonyms: MIMOSINE;L(-)-MIMOSINE;LEUCENOL;leucenine;NSC 69188;L-MIMOSINE;L-LEUCININE;Mimosine 99%;Mimosine,99%;MimosineLeucenol

CBNumber:: CB1234466

Molecular Formula:: C8H10N2O4

Molecular Weight:: 198.18

MDL Number:: MFCD00075909

MOL File:: 500-44-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:16:56

Product description	Number	Pack Size	Price
L-Mimosine from Koa hoale seeds ≥98%	M0253	25mg	$36.8
L-Mimosine from Koa hoale seeds ≥98%	M0253	1g	$420.75
L-Mimosine ≥98%	14337	25mg	$28
L-Mimosine ≥98%	14337	50mg	$42
L-Mimosine ≥98%	14337	100mg	$69
More product size

Request For Quotation

L-MIMOSINE Properties

Melting point	224-228 °C
Boiling point	335.48°C (rough estimate)
Density	1.3764 (rough estimate)
refractive index	1.6180 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Water (Slightly, Heated, Sonicated)
form	Pink to brown powder.
pka	2.06±0.10(Predicted)
color	White to Off-White
Merck	13,6221
InChI	InChI=1/C8H10N2O4/c9-5(8(13)14)3-10-2-1-6(11)7(12)4-10/h1-2,4-5,12H,3,9H2,(H,13,14)/t5-/s3
InChIKey	WZNJWVWKTVETCG-YFKPBYRVSA-N
SMILES	C(N1C=CC(=O)C(O)=C1)[C@H](N)C(=O)O \|&1:9,r\|
LogP	-1.080 (est)
CAS DataBase Reference	500-44-7(CAS DataBase Reference)
FDA UNII	Z46B1LUI5N
EPA Substance Registry System	Mimosine (500-44-7)
UNSPSC Code	12352209
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332

Precautionary statements

P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

20/21/22

Safety Statements

22-36

WGK Germany

HS Code

29333990

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

Hazardous Substances Data

500-44-7(Hazardous Substances Data)

NFPA 704

	0
3		0

L-MIMOSINE price More Price(48)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M0253	L-Mimosine from Koa hoale seeds ≥98%	500-44-7	25mg	$36.8	2026-04-30	Buy
Sigma-Aldrich	M0253	L-Mimosine from Koa hoale seeds ≥98%	500-44-7	1g	$420.75	2026-04-30	Buy
Cayman Chemical	14337	L-Mimosine ≥98%	500-44-7	25mg	$28	2026-04-30	Buy
Cayman Chemical	14337	L-Mimosine ≥98%	500-44-7	50mg	$42	2026-04-30	Buy
Cayman Chemical	14337	L-Mimosine ≥98%	500-44-7	100mg	$69	2026-04-30	Buy

Product number	Packaging	Price	Buy
M0253	25mg	$36.8	Buy
M0253	1g	$420.75	Buy
14337	25mg	$28	Buy
14337	50mg	$42	Buy
14337	100mg	$69	Buy

L-MIMOSINE Chemical Properties,Uses,Production

Description

This alkaloid was isolated by Renz from Mimosia pudica L. and also from Leucaena glauca Benth. It is laevorotatory with [α]²²_D - 21 ° (H20) and yields a blue, crystalline copper salt. On heating the chloride under pressure, a sublimate is formed which has been shown, by comparison with a synthetic specimen, to be N-methyl-3-hydroxypyrid-4-one, m.p. 224°C. The alkaloid is toxic and in horses produces loss of hair when administered in large doses.

Chemical Properties

light tan to pink crystalline powder

Uses

L-Mimosine from Koa hoale seeds has been used to study its anti-inflammatory effect in chronic inflammatory response (potassium permanganate - induced chronic granuloma).

Definition

ChEBI: An L-alpha-amino acid that is propionic acid substituted by an amino group at position 2 and a 3-hydroxy-4-oxopyridin-1(4H)-yl group at position 3 (the 2S-stereoisomer). It a non-protein plant amino acid isolated from Mimosa pudica.

General Description

L-mimosine [β-N (3-hydroxy-4-pyridone)-α-amino propionic acid] is a non-protein amino acid and is a vital component of tropical legumes, such as Leucaena glauca and other legumes belonging to Mimosa spp. Structurally L-mimosine resembles dihydroxyphenylalanine except 3,4-dihydroxy-phenyl ring replaced by 3-hydroxy-4-pyridone ring.

Biochem/physiol Actions

L-Mimosine is a plant amino acid and potential inhibitor of the cell cycle giving rise to growth arrest in G1-phase. It is an iron chelator that inhibits DNA replication in mammalian cells. L-Mimosine has been shown to promote apoptosis in xenotransplanted human pancreatic cancer. L-Mimosine stabilizes hypoxia inducible factor 1 (HIF-1) and stimulates the expression of B-cell translocation gene 2 (Btg2) and N-myc downstream regulated gene 1 (Ndrg1) at the transcriptional level, which reduce cell proliferation of prostate carcinoma cells in vitro. L-Mimosine stabilizes HIF-1 through the inhibition of prolyl hydroxylases (PHDs) which target HIF-1 through degradation. The mechanism of inhibition is likely through the chelation of Fe2+ bound to the active site of PHD which is required for enzymatic activity. Mimosine inhibits cell cycle progression via iron chelation in MDA-MB-453 human breast cancer cells. Mimosine, hinder folate metabolism in cell-specific manner.

References

Renz., Zeit. physiol. Chem., 244, 153 (1936)
Nienburg, Taubock., ibid, 250,80 (1937)
Kostermanns., Rec. trav. Chim. Pays-Bas, 65, 319 (1946)
Kostermann., ibid, 66,93 (1947)

L-MIMOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

L-MIMOSINE Suppliers

Global( 181)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3619	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29815	58
Chengdu Biopurify Phytochemicals Ltd.	+86-28-82633860; +8618080483897	sales@biopurify.com	China	4616	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49979	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 +86-17392581500	1015@dideu.com	China	3991	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	9542	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	8741	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Chengdu Biopurify Phytochemicals Ltd.	58
BOC Sciences	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
TargetMol Chemicals Inc.	58
Shanghai UCHEM Inc.	58
InvivoChem	58

View Lastest Price from L-MIMOSINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-11	Mimosine 500-44-7			99.48%	10g	TargetMol Chemicals Inc.
2025-04-04	L-MIMOSINE 500-44-7		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-08-12	L-MIMOSINE 500-44-7	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd

Mimosine
500-44-7
$0.00
99.48%
TargetMol Chemicals Inc.

L-MIMOSINE
500-44-7
98%
Henan Aochuang Chemical Co.,Ltd.

L-MIMOSINE
500-44-7
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

L-MIMOSINE Spectrum

L-MIMOSINE(500-44-7)¹HNMR L-MIMOSINE(500-44-7)IR L-MIMOSINE(500-44-7)Raman L-MIMOSINE(500-44-7)FT-IR

500-44-7(L-MIMOSINE)Related Search:

VERRUCULOGEN REVEROMYCIN A Tangeretin MALVIDIN CHLORIDE TRYPROSTATIN A

L-MIMOSINE 2,3-Diaminopropionic acid (2S)-2-Amino-3-dimethylaminopropanoic acid L-2,3-Diaminopropionic acid 3-(N-Methylamino)-L-alanine

4-HYDROXYPYRIDINE Oxamic acid L-Mimosine (leucenol),L-Mimosine (leucenol) azaleucine DL-MIMOSINE,DL-MIMOSINE

BOC-L-MIMOSINE,BOC-L-MIMOSINE MIMOSA EXTRACT/ MIMOSINE,MIMOSA EXTRACT/ MIMOSINE FMOC-L-MIMOSINE,FMOC-L-MIMOSINE

1of4

L-LEUCININE L-MIMOSINE BETA-[N-(3-HYDROXY-4-PYRIDONE)]-ALPHA-AMINOPROPIONIC ACID LEUCENOL ALPHA-AMINO-BETA-[N-(3-HYDROXY-4-PYRIDONE)]-PROPIONIC ACID (S)-ALPHA-AMINO-BETA-(1-[3-HYDROXY-4-OXOPYRIDINE])PROPIONIC ACID (s)-1(4h)-pyridinepropanoicaci -2-Amino-3-(3-hydroxy-4-oxopyridin-1(4H) L-Mimosine, 98%, from Koa hoale seeds leucenine (S)-alpha-amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid MIMOSINE, 98% (LEUCENOL, OPTICALLY ACTIV E) L-MIMOSINE FROM KOA HOALE SEEDS MIMOSINE extrapure for biochemistry L-Mimosine from Koa hoale seeds, Leucenol, optically active, Leucenol, α-Amino-β-(N-[3-hydroxy-4-pyridone])propionic acid: Leucenol, (S)-α-Amino-β-[1-(3-hydroxy-4-oxopyridine)]propionic acid Mimosine 99% [αR,(+)]-α-Amino-3-hydroxy-4-oxo-1(4H)-pyridinepropionic acid Mimosine,99% MimosineLeucenol L(-)-Mimosine[β-[N-(3-Hydroxy-4-pyridone)]-α-aminopropionic Acid] (s)-α-amino-β-[1-(3-hydroxy-4-oxopyridine)]propionic acid L-Mimosine from Koa hoale seeds,(S)-α-Amino-β-[1-(3-hydroxy-4-oxopyridine)]propionic acid, Leucenol (S)-2-aMino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)propanoic acid NSC 69188 Leucenol, optically active α-Amino-β-(N-[3-hydroxy-4-pyridone])propionic acid 1(4H)-Pyridinepropanoicacid, a-amino-3-hydroxy-4-oxo-, (aS)- 1(4H)-Pyridinepropanoic acid, α-amino-3-hydroxy-4-oxo-, (αS)- Mimosine extrapure L-Mimosine, non-protein amino acid L-Mimosine from Koa hoale seeds L(-)-MIMOSINE MIMOSINE 500-44-7 Cell Cycle Regulators Cell Cycle Cell Signaling and Neuroscience Cell Biology BioChemical Apoptosis and Cell Cycle Inhibitors Alkaloids