ChemicalBook >> CAS DataBase List >>Tetramethylammonium fluoride
Tetramethylammonium fluoride
- CAS No.
- 373-68-2
- Chemical Name:
- Tetramethylammonium fluoride
- Synonyms
- TetraMethylaMMoniuM fluorid;Tetramethylaminium·fluoride;Tetramethylazanium fluoride;TETRAMETHYLAMMONIUM FLUORIDE;Tetramethylammonium Fluoridede;Tetramethylammonium fluoride (7CI);n,n,n-trimethyl-methanaminiufluoride;N,N,N-Trimethylmethanaminium fluoride;Tetramethylammonium fluoride, anhydrous;Methanaminium, N,N,N-trimethyl-, fluoride
- CBNumber:
- CB1235483
- Molecular Formula:
- C4H12FN
- Molecular Weight:
- 93.14
- MDL Number:
- MFCD00011627
- MOL File:
- 373-68-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-24 14:58:38
| Product description | Number | Pack Size | Price |
| Tetramethylammonium fluoride 97% | 459135 | 1g | $121 |
| Tetramethylammonium fluoride 97% | 459135 | 5g | $567 |
| Tetramethylammonium fluoride | T303855 | 500mg | $45 |
| Tetramethylammonium fluoride | T303855 | 1g | $50 |
| Tetramethylammonium fluoride, anhydrous 97% | 3133-3-10 | 250mg | $65 |
| More product size | |||
| Melting point | 170 °C (dec.) (lit.) |
|---|---|
| storage temp. | Store at room temperature |
| form | solid |
| Appearance | White to off-white <39°C Solid,>42°C Liquid |
| InChI | InChI=1S/C4H12N.FH/c1-5(2,3)4;/h1-4H3;1H/q+1;/p-1 |
| InChIKey | HQFTZNVQVRRDLN-UHFFFAOYSA-M |
| SMILES | [N+](C)(C)(C)C.[F-] |
| CAS DataBase Reference | 373-68-2(CAS DataBase Reference) |
| EPA Substance Registry System | Tetramethylammonium fluoride (373-68-2) |
| UNSPSC Code | 12352116 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29239000 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
Tetramethylammonium fluoride price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 459135 | Tetramethylammonium fluoride 97% | 373-68-2 | 1g | $121 | 2026-04-30 | Buy |
| Sigma-Aldrich | 459135 | Tetramethylammonium fluoride 97% | 373-68-2 | 5g | $567 | 2026-04-30 | Buy |
| TRC | T303855 | Tetramethylammonium fluoride | 373-68-2 | 500mg | $45 | 2021-12-16 | Buy |
| TRC | T303855 | Tetramethylammonium fluoride | 373-68-2 | 1g | $50 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3133-3-10 | Tetramethylammonium fluoride, anhydrous 97% | 373-68-2 | 250mg | $65 | 2021-12-16 | Buy |
Tetramethylammonium fluoride Chemical Properties,Uses,Production
Description
Tetramethylammonium fluoride is the quaternary ammonium salt with the formula (CH3)4NF. This hygroscopic white solid is a source of "naked fluoride", that is fluoride ions not connected to a metal atom in a complex. Most other soluble salts of fluoride are in fact bifluorides, HF2–. Historically, there has been two main approaches to prepare TMAF:
(i) Via neutralization of tetramethylammonium hydroxide (TMAOH) with HF.
(ii) through the metathesis reaction of different ammonium salts with inorganic sources of fluoride such as KF or CsF.
Due to the high basicity of the fluoride anion, the salt reacts slowly with acetonitrile, inducing its dimerization to CH3C(NH2)=CHCN, which co-crystallizes.
Uses
Tetramethylammonium fluoride may be used in combination with sulfuryl fluoride for the conversion of aryl phenols to aryl fluorides. It can react with aminosilanes to generate onium amide bases in situ, which can deprotonate heteroarenes.
Uses
Reactant for:
- Halide-induced ring opening of 2-substituted aziridinium salts
- Synthesis of fluoro aromatics via fluorodenitration reactions
- Synthesis of sevoflurane in ionic liquids by halogen-exchange fluorination
- Synthesis of fluorinated Poly(oxomolybdates)
Tetramethylammonium fluoride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 224)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from Tetramethylammonium fluoride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-30 | Tetramethylammonium fluoride
373-68-2
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-03-20 | Tetramethylammonium fluoride tetrahydrate
373-68-2
|
US $19.90 / kg | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2021-08-12 | Tetramethylammonium fluoride
373-68-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Tetramethylammonium fluoride
373-68-2
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Tetramethylammonium fluoride tetrahydrate
373-68-2
- US $19.90 / kg
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Tetramethylammonium fluoride
373-68-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
373-68-2(Tetramethylammonium fluoride)Related Search:
Tetramethylammonium hydroxide
Tetramethylammonium hydroxide pentahydrate
Tetramethylammonium fluoride tetrahydrate
Octamethylcyclotetrasiloxane
Methyl tetrahydrophthalic anhydride
FLUORIDE STANDARD
Ammonium fluoride
N,N,N',N'-Tetramethylethylenediamine
Tetramethylpyrazine
Tetramethylammonium acetate
1of4
Tetramethylammonium Fluoridede
n,n,n-trimethyl-methanaminiufluoride
TETRAMETHYLAMMONIUM FLUORIDE
Tetramethylammoniumfluoride,20%AqueousSolution
Tetramethylammonium fluoride, anhydrous
Methanaminium, N,N,N-trimethyl-, fluoride
Tetramethylazanium fluoride
Tetramethylaminium·fluoride
TetraMethylaMMoniuM fluorid
N,N,N-Trimethylmethanaminium fluoride
Tetramethylammonium fluoride ISO 9001：2015 REACH
373-68-2 Tetramethylammonium fluoride C4H12FN
Tetramethylammonium fluoride (7CI)
TETRAMETHYLAMMONIUM FLUORIDE (CONTAINS LESS THAN ONE WATER)
373-68-2
C4H12NF
CH34NF
Protection and Derivatization
Synthetic Reagents
Deprotection
Fluoride Sources
Deprotecting Reagents
Fluoride Sources
Protection and Derivatization
quarternary ammonium salts
