METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE
- CAS No.
- 78155-74-5
- Chemical Name:
- METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE
- Synonyms
- Methyl 5-bromo-1H-indazol...;5-Bromo-3-(methoxycarbonyl)-1H-indazole;METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE;1H-Indazole-3-carboxylicacid,5-broMo-,Methylester;5-Bromo-1H-indazole-3-carboxylic acid methyl ester
- CBNumber:
- CB1241488
- Molecular Formula:
- C9H7BrN2O2
- Molecular Weight:
- 255.07
- MDL Number:
- MFCD07371572
- MOL File:
- 78155-74-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Methyl 5-bromo-1H-indazole-3-carboxylate ≥95%(Assay) | 20777 | 100MG | $65.4 |
| Methyl 5-bromo-1H-indazole-3-carboxylate ≥95%(Assay) | 20777 | 1G | $81.52 |
| Methyl 5-bromo-1H-indazole-3-carboxylate ≥95%(Assay) | 20777 | 5G | $286.63 |
| Methyl 5-bromo-1H-indazole-3-carboxylate | 068467 | 1.00g | $530 |
| Methyl 5-bromo-1H-indazole-3-carboxylate | 068467 | 5.00g | $1340 |
| More product size | |||
| Melting point | 208-210℃ |
|---|---|
| Boiling point | 399.7±22.0 °C(Predicted) |
| Density | 1.709 |
| storage temp. | 2-8°C |
| pka | 10.67±0.40(Predicted) |
| Appearance | off-white solid |
| InChI | InChI=1S/C9H7BrN2O2/c1-14-9(13)8-6-4-5(10)2-3-7(6)11-12-8/h2-4H,1H3,(H,11,12) |
| InChIKey | WVNKCZKRGOOMNU-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(Br)C=C2)C(C(OC)=O)=N1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P271-P260-P280 |
| HS Code | 2933998090 |
METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Chem-Impex | 20777 | Methyl 5-bromo-1H-indazole-3-carboxylate ≥95%(Assay) | 78155-74-5 | 100MG | $65.4 | 2026-05-19 | Buy |
| Chem-Impex | 20777 | Methyl 5-bromo-1H-indazole-3-carboxylate ≥95%(Assay) | 78155-74-5 | 1G | $81.52 | 2026-05-19 | Buy |
| Chem-Impex | 20777 | Methyl 5-bromo-1H-indazole-3-carboxylate ≥95%(Assay) | 78155-74-5 | 5G | $286.63 | 2026-05-19 | Buy |
| Matrix Scientific | 068467 | Methyl 5-bromo-1H-indazole-3-carboxylate | 78155-74-5 | 1.00g | $530 | 2026-05-18 | Buy |
| Matrix Scientific | 068467 | Methyl 5-bromo-1H-indazole-3-carboxylate | 78155-74-5 | 5.00g | $1340 | 2026-05-18 | Buy |
METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE Chemical Properties,Uses,Production
Uses
Methyl 5-bromo-1H-indazole-3-carboxylate is an indole azole compound containing a five-membered heteroaromatic ring structure and can be used in organic synthesis. Its derivatives can also be used to treat or prevent herpes virus infection in patients.
Synthesis
1077-94-7
67-56-1
78155-74-5
Step 2: Concentrated sulfuric acid (1 mL) was slowly added to a suspension of 5-bromo-1H-indazole-3-carboxylic acid (1.30 g, 5.39 mmol) in anhydrous methanol (50 mL) under argon protection. The reaction mixture was heated to reflux for 4 hours. Upon completion of the reaction, the solution was cooled to room temperature and subsequently evaporated under reduced pressure to remove methanol. The residue was dissolved in ethyl acetate and washed with deionized water. The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated to afford methyl 5-bromo-1H-indazole-3-carboxylate (1.35 g, 5.29 mmol, 98% yield) as a white solid. The product was confirmed by 1H NMR (DMSO-d6): δ 14.13 (s, 1H), 8.21 (d, J = 1.6 Hz, 1H), 7.67 (d, J = 7.2 Hz, 1H), 7.59 (dd, J = 7.2, 1.2 Hz, 1H), 3.92 (s, 3H); ESIMS analysis result: C9H7BrN2O2 m/z 256.0 (M + H).
References
[1] Patent: WO2013/40215, 2013, A1. Location in patent: Paragraph 00340
[2] Patent: US2015/266825, 2015, A1. Location in patent: Paragraph 1359; 1361
[3] Patent: WO2018/75858, 2018, A1. Location in patent: Paragraph 0371; 0373
[4] European Journal of Organic Chemistry, 2007, # 29, p. 4909 - 4916
[5] Patent: CN107573327, 2018, A. Location in patent: Paragraph 0071; 0072; 0073; 0074
METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Rokechem Technology Co., Ltd. | 18758118018 | sales001@rokechem.com | China | 255 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
View Lastest Price from METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2022-09-20 | Methyl 5-bromo-1H-indazole-3-carboxylate
78155-74-5
|
1kg | 98%min | 1-10000kgs | Changzhou Rokechem Technology Co., Ltd. | ||
 |
2019-07-10 | METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE
78155-74-5
|
$1.00 | 1KG | 98% | 150KG | Career Henan Chemical Co |
-
- Methyl 5-bromo-1H-indazole-3-carboxylate
78155-74-5
- 98%min
- Changzhou Rokechem Technology Co., Ltd.
-
- METHYL 5-BROMO-1H-INDAZOLE-3-CARBOXYLATE
78155-74-5
- $1.00
- 98%
- Career Henan Chemical Co
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