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ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE structure

CAS No.: 43088-42-2

Chemical Name:: ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE

Synonyms: methyl 2-amino-4-methylthiophene-3-carboxylate;BUTTPARK 29\08-49;2-aMino-4-Methylthiophene-3-carboxylate;2-Amino-3-(ethoxycarbonyl)-4-methylthiophene;thyl 2-amino-4-methylthiophene-3-carboxylate;Ethyl 2-amino-4-methyl-3-thiophenecarboxylate;ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE;Eethyl 2-amino-4-methylthiophene-3-carboxylate;2-aMino-5-ethyl-4-Methylthiophene-3-carboxylate;Ethyl 2-Amino-4-methylthiophene-3-carboxylate >

CBNumber:: CB1241998

Molecular Formula:: C8H11NO2S

Molecular Weight:: 185.24

MDL Number:: MFCD00051669

MOL File:: 43088-42-2.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:09

Product description	Number	Pack Size	Price
Ethyl 2-Amino-4-methylthiophene-3-carboxylate >98.0%(GC)(T)	E1103	1g	$29
Ethyl 2-Amino-4-methylthiophene-3-carboxylate >98.0%(GC)(T)	E1103	5g	$136
Ethyl 2-amino-4-methylthiophene-3-carboxylate ≥98%(GC)	44274	1G	$42.16
Ethyl 2-amino-4-methylthiophene-3-carboxylate ≥98%(GC)	44274	5G	$192.19
Ethyl 2-amino-4-methylthiophene-3-carboxylate	062874	5.00g	$78
More product size

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ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Properties

Melting point	80 °C
Boiling point	279℃
Density	1.219
Flash point	123℃
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Water Solubility	Soluble in water
pka	0.24±0.10(Predicted)
form	powder to crystal
color	Light yellow to Yellow to Orange
BRN	1366073
InChI	InChI=1S/C8H11NO2S/c1-3-11-8(10)6-5(2)4-12-7(6)9/h4H,3,9H2,1-2H3
InChIKey	ILYCZKOBLRJJSW-UHFFFAOYSA-N
SMILES	C1(N)SC=C(C)C=1C(OCC)=O
CAS DataBase Reference	43088-42-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Safety Statements

24/25

HazardClass

IRRITANT

HS Code

29349990

NFPA 704

	1
2		0

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	E1103	Ethyl 2-Amino-4-methylthiophene-3-carboxylate >98.0%(GC)(T)	43088-42-2	1g	$29	2026-04-30	Buy
TCI Chemical	E1103	Ethyl 2-Amino-4-methylthiophene-3-carboxylate >98.0%(GC)(T)	43088-42-2	5g	$136	2026-04-30	Buy
Chem-Impex	44274	Ethyl 2-amino-4-methylthiophene-3-carboxylate ≥98%(GC)	43088-42-2	1G	$42.16	2026-05-19	Buy
Chem-Impex	44274	Ethyl 2-amino-4-methylthiophene-3-carboxylate ≥98%(GC)	43088-42-2	5G	$192.19	2026-05-19	Buy
Matrix Scientific	062874	Ethyl 2-amino-4-methylthiophene-3-carboxylate	43088-42-2	5.00g	$78	2026-05-18	Buy

Product number	Packaging	Price	Buy
E1103	1g	$29	Buy
E1103	5g	$136	Buy
44274	1G	$42.16	Buy
44274	5G	$192.19	Buy
062874	5.00g	$78	Buy

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Chemical Properties,Uses,Production

Application

2-Amino-4-methyl-thiophene-3-carboxylic acid ethyl ester is an ester organic compound that can be used as a pharmaceutical intermediate.

Chemical Properties

Yellow solid

Synthesis

105-56-6

67-64-1

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE

43088-42-2

GENERAL METHOD: Cyclohexanone (1.06 mL, 10 mmol), ethyl cyanoacetate (1.15 mL, 10 mmol), morpholine (0.90 mL, 10 mmol), and sulfur powder (0.32 g, 10 mmol) were dissolved in ethanol (10 mL), and the reaction was stirred and refluxed overnight. After completion of the reaction, the mixture was cooled to room temperature and the solvent was removed by distillation under reduced pressure. The resulting crude product was washed with cold ethanol, filtered through a sintered funnel and dried under vacuum. The dried crude product was dissolved in dichloromethane and washed with saturated saline. The organic layer was separated and concentrated under reduced pressure to afford the target compound ethyl 2-amino-4-methylthiophene-3-carboxylate (2a) in 73% yield (1.83 g).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 13, p. 4418 - 4427
[2] European Journal of Medicinal Chemistry, 2014, vol. 86, p. 270 - 278
[3] Patent: CN107151251, 2017, A. Location in patent: Paragraph 0006; 0010
[4] Organic and Biomolecular Chemistry, 2014, vol. 12, # 24, p. 4233 - 4242
[5] Journal of Molecular Catalysis B: Enzymatic, 2013, vol. 95, p. 29 - 35

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE synthesis

Synthesis of ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE from Ethyl cyanoacetate and Acetone

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Preparation Products And Raw materials

Raw materials

tert-Butyl acetoacetate Sulfur Ethanol Morpholine Ethyl cyanoacetate

Diethylamine Acetone

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Preparation Products

3-Thiophenecarboxylic acid, 2-amino-5-bromo-4-methyl-, ethyl ester 4-METHYLTHIOPHENE-3-CARBOXYLIC ACID

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Suppliers

Global( 204)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29816	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4241	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10404	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8828	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Changzhou Ansciep Chemical Co., Ltd.	58
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58
Neostar United (Changzhou) Industrial Co., Ltd.	58

View Lastest Price from ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE 43088-42-2	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
2021-08-12	ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE 43088-42-2	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-08-06	ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE 43088-42-2	US $1.00 / KG	1KG	98%	10KG	Career Henan Chemical Co

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE
43088-42-2
US $1.10 / g
99.00%
Dideu Industries Group Limited

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE
43088-42-2
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE
43088-42-2
US $1.00 / KG
98%
Career Henan Chemical Co

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Spectrum

ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE(43088-42-2)¹HNMR

43088-42-2(ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE)Related Search:

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2-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER ETHYL 2-AMINO-5-METHYLTHIOPHENE-3-CARBOXYLATE 4-METHYLTHIOPHENE-3-CARBOXYLIC ACID Ethyl thiophene-3-carboxylate ETHYL 2-[(2-CHLOROACETYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXYLATE

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ETHYL 2-[(2,2-DICHLOROACETYL)AMINO]-4-METHYLTHIOPHENE-3-CARBOXYLATE AKOS 89941 ETHYL 2-[2-(2,4-DICHLOROPHENOXY)ACETAMIDO]-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE

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BUTTPARK 29\08-49 ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE Ethyl 2-amino-4-methyl-3-thiophenecarboxylate 2-AMINO-4-METHYL-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER Ethyl 2-amino-4-methylthiophene-3-carboxylate, 98+% Ethyl 2-amino-4-methylthiophene-3-carboxylate ,97% 2-Amino-3-(ethoxycarbonyl)-4-methylthiophene 2-aMino-4-Methylthiophene-3-carboxylate 2-aMino-5-ethyl-4-Methylthiophene-3-carboxylate 2-amino-4-methyl-3-thiophenecarboxylic acid ethyl ester 3-thiophenecarboxylic acid, 2-amino-4-methyl-, ethyl ester methyl 2-amino-4-methylthiophene-3-carboxylate 2-Amino-3-(ethoxycarbonyl)-4-methylthiophene, Ethyl 2-amino-4-methyl-3-thenoate thyl 2-amino-4-methylthiophene-3-carboxylate Ethyl 2-Amino-4-methylthiophene-3-carboxylate > ETHYL 2-AMINO-4-METHYLTHIOPHENE-3-CARBOXYLATE ISO 9001：2015 REACH Eethyl 2-amino-4-methylthiophene-3-carboxylate 43088-42-2 Thiophene