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ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE structure

CAS No.: 13720-94-0

Chemical Name:: ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE

Synonyms: NSC 136916;NSC 109461;AURORA 18125;4-CHLORO-3-QUINOLINECARBOXYLATE;ETHYL 4-CHLOROQUINOLINE-3-CARBOXYLATE;ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE;4-CHLORO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;3-Quinolinecarboxylic acid, 4-chloro-, ethyl ester;4-chloro-3-Quinolinecarboxylic acid ethyl ester (6CI 8CI 9CI ACI);3-Quinolinecarboxylic acid, 4-chloro-, ethyl ester (6CI, 8CI, 9CI, ACI)

CBNumber:: CB1245057

Molecular Formula:: C12H10ClNO2

Molecular Weight:: 235.67

MDL Number:: MFCD00173407

MOL File:: 13720-94-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:10

Product description	Number	Pack Size	Price
Ethyl 4-chloroquinoline-3-carboxylate Aldrich	JRD0194	1g	$304
Ethyl 4-Chloroquinoline-3-carboxylate	E1201	200MG	$41
Ethyl 4-Chloroquinoline-3-carboxylate	E1201	1G	$188
ethyl 4-chloroquinoline-3-carboxylate 97.0%	E19143	1g	$29
ethyl 4-chloroquinoline-3-carboxylate 97.0%	E19143	5g	$70
More product size

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ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE Properties

Melting point	46-48°C
Boiling point	128-129 °C(Press: 0.2 Torr)
Density	1.286
storage temp.	Storage temp. -20°C
pka	1.78±0.24(Predicted)
form	powder to crystal
color	White to Orange to Green
InChI	1S/C12H10ClNO2/c1-2-16-12(15)9-7-14-10-6-4-3-5-8(10)11(9)13/h3-7H,2H2,1H3
InChIKey	DWXQUAHMZWZXHP-UHFFFAOYSA-N
SMILES	CCOC(=O)c1cnc2ccccc2c1Cl
CAS DataBase Reference	13720-94-0(CAS DataBase Reference)
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P305+P351+P338

Hazard Codes

Risk Statements

36/37/38-36

Safety Statements

26-36/37/39

WGK Germany

HazardClass

IRRITANT

HS Code

2933499090

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2

NFPA 704

	1
0		0

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE price More Price(41)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	JRD0194	Ethyl 4-chloroquinoline-3-carboxylate Aldrich	13720-94-0	1g	$304	2026-04-30	Buy
TCI Chemical	E1201	Ethyl 4-Chloroquinoline-3-carboxylate	13720-94-0	200MG	$41	2026-04-30	Buy
TCI Chemical	E1201	Ethyl 4-Chloroquinoline-3-carboxylate	13720-94-0	1G	$188	2024-03-01	Buy
Synthonix	E19143	ethyl 4-chloroquinoline-3-carboxylate 97.0%	13720-94-0	1g	$29	2026-05-06	Buy
Synthonix	E19143	ethyl 4-chloroquinoline-3-carboxylate 97.0%	13720-94-0	5g	$70	2026-05-06	Buy

Product number	Packaging	Price	Buy
JRD0194	1g	$304	Buy
E1201	200MG	$41	Buy
E1201	1G	$188	Buy
E19143	1g	$29	Buy
E19143	5g	$70	Buy

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE Chemical Properties,Uses,Production

Uses

Ethyl 4-chloroquinoline-3-carboxylate is used as organic chemical synthesis intermediate.

Synthesis

4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

26892-90-0

13720-94-0

Synthesis of ethyl 4-chloroquinoline-3-carboxylate (A2): ethyl 4-hydroxyquinoline-3-carboxylate (A1) (1.5 g, 7 mmol) solid was placed in a reaction vial and phosphorus oxychloride (POCl3) (2.2 g, 1.3 mL, 14 mmol) was added. The reaction mixture was heated at 110 °C for 20 min. Upon completion of the reaction, the mixture was slowly poured into a pre-cooled mixture of aqueous ammonia solution (28-30%) and ice and stirred until a granular solid was formed. The reaction mixture was extracted with ether (3 x 40 mL), the organic layers were combined, dried with anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give an oily product. After standing, the product crystallized (1.44 g, 6 mmol, 87% yield) and could be used for subsequent reactions without further purification.

References

[1] Journal of Medicinal Chemistry, 2006, vol. 49, # 21, p. 6351 - 6363
[2] Patent: WO2005/123686, 2005, A1. Location in patent: Page/Page column 75-76
[3] European Journal of Medicinal Chemistry, 2015, vol. 103, p. 1 - 16
[4] Patent: CN108623589, 2018, A. Location in patent: Paragraph 0142; 0149
[5] Patent: CN108623581, 2018, A. Location in patent: Page/Page column 7

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE Preparation Products And Raw materials

Raw materials

4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Ammonia

Preparation Products

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE Suppliers

Global( 148)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10000	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4017	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
career henan chemical co	58
Fuxin Pharmaceutical	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Shanxi Xuanran Import and Export Trade Co., Ltd.	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Zhejiang J&C Biological Technology Co.,Limited	58

View Lastest Price from ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-08-12	ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE 13720-94-0	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
	2020-01-09	ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE 13720-94-0	US $0.01 / KG	500g	98%; 99%	500g；1kg； 10kg; 25kg	Career Henan Chemical Co

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE
13720-94-0
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE
13720-94-0
US $0.01 / KG
98%; 99%
Career Henan Chemical Co

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE Spectrum

ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE(13720-94-0)¹HNMR

13720-94-0(ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE)Related Search:

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AURORA 18125 ETHYL 4-CHLORO-3-QUINOLINECARBOXYLATE ETHYL 4-CHLOROQUINOLINE-3-CARBOXYLATE 4-CHLORO-3-QUINOLINECARBOXYLATE 4-CHLORO-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER NSC 109461 NSC 136916 3-Quinolinecarboxylic acid, 4-chloro-, ethyl ester 3-Quinolinecarboxylic acid, 4-chloro-, ethyl ester (6CI, 8CI, 9CI, ACI) 4-chloro-3-Quinolinecarboxylic acid ethyl ester (6CI 8CI 9CI ACI) 13720-94-0 ESTER Acids and Derivatives Heterocycles