1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
- CAS No.
- 3697-68-5
- Chemical Name:
- 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
- Synonyms
- ethyl 1-(hydroxymethyl)cyclopropane-1-carboxylate;Ethyl 1-(hydroxymethyl);1,1 Cyclopropane dicarboxylic acid ethyl ester;Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate;Ethyl1-(hydroxymethyl)cyclopropanecarboxylate,97%;1-Hydroxymethyl-cyclopropanecarboxylic ethyl ester;Ethyl 1-(hydroxyMethyl)cyclopropanecarboxylate, 97%;1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER;Cyclopropanecarboxylic acid, 1-(hydroxyMethyl)-, ethyl ester;1-(hydroxymethyl)-Cyclopropanecarboxylic acid ethyl ester (7CI 8CI 9CI ACI)
- CBNumber:
- CB12456914
- Molecular Formula:
- C7H12O3
- Molecular Weight:
- 144.17
- MDL Number:
- MFCD09759206
- MOL File:
- 3697-68-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | OR480832 | 1g | $98 |
| Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | OR480832 | 5g | $311 |
| Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | E43821 | 100mg | $21 |
| Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | E43821 | 250mg | $26 |
| Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | E43821 | 1g | $30 |
| Boiling point | 90-94 °C(Press: 8 Torr) |
|---|---|
| Density | 1.159±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 15.10±0.10(Predicted) |
| Appearance | Colorless to light yellow Liquid |
| InChI | InChI=1S/C7H12O3/c1-2-10-6(9)7(5-8)3-4-7/h8H,2-5H2,1H3 |
| InChIKey | PAILVKQSHRJIPE-UHFFFAOYSA-N |
| SMILES | C1(CO)(C(OCC)=O)CC1 |
| CAS DataBase Reference | 3697-68-5 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| HS Code | 2918199890 | |||||||||
| NFPA 704 |
|
1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR480832 | Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | 3697-68-5 | 1g | $98 | 2026-06-04 | Buy |
| Apolloscientific | OR480832 | Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | 3697-68-5 | 5g | $311 | 2026-06-04 | Buy |
| Synthonix | E43821 | Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | 3697-68-5 | 100mg | $21 | 2026-05-06 | Buy |
| Synthonix | E43821 | Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | 3697-68-5 | 250mg | $26 | 2026-05-06 | Buy |
| Synthonix | E43821 | Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate 95% | 3697-68-5 | 1g | $30 | 2026-05-06 | Buy |
1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER Chemical Properties,Uses,Production
Uses
Ethyl 1-(hydroxymethyl)cyclopropanecarboxylate acts as a ligand for Suzuki coupling reaction.
Synthesis
1559-02-0
3697-68-5
Example 64 Preparation of ethyl 1-(hydroxymethyl)cyclopropanecarboxylate A tetrahydrofuran solution of 1 M tri-tert-butoxy lithium aluminum (70.90 mL, 70.90 mmol) was slowly added dropwise to a stirred solution of diethyl cyclopropane-1,1-dicarboxylate (6 g, 32.20 mmol) in tetrahydrofuran (129 mL). The reaction system was stirred at 23 °C and gradually warmed to 65 °C and maintained at this temperature for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched with 10% sodium bisulfate solution (275 mL) and subsequently extracted with ether. The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford the light yellow oily target product ethyl 1-(hydroxymethyl)cyclopropanecarboxylate (4.60 g, 91% yield). The product was characterized by 1H NMR (300 MHz, CDCl3): δ 4.16 (q, J = 7 Hz, 2H), 3.62 (s, 2H), 2.60 (br s, 1H), 1.22-1.30 (m, 5H), 0.87 (dd, J = 7, 4 Hz, 2H).
References
[1] Patent: US2012/110702, 2012, A1. Location in patent: Page/Page column 38
[2] Patent: US2013/109566, 2013, A1. Location in patent: Paragraph 0400; 0401
[3] Patent: US2013/288893, 2013, A1. Location in patent: Paragraph 0450-0451
[4] Patent: US2016/60245, 2016, A1. Location in patent: Paragraph 0451; 0452
[5] Patent: US2012/53146, 2012, A1. Location in patent: Paragraph 0170; 0171
1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials
1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3999 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | +86-519-85525359 +86-15995072465 | sales@xuanmingchem.com | China | 912 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 17259 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5899 | 58 |
View Lastest Price from 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-07-20 | 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
3697-68-5
|
$1.00 | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2022-09-27 | 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
3697-68-5
|
1kg | 99% | 1000kg | henan kanbei chemical co.,ltd | ||
 |
2019-07-06 | 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
3697-68-5
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
3697-68-5
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
3697-68-5
- $0.00
- 99%
- henan kanbei chemical co.,ltd
-
- 1-HYDROXYMETHYL-CYCLOPROPANECARBOXYLIC ACID ETHYL ESTER
3697-68-5
- $1.00
- 99%
- Career Henan Chemical Co
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