1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL
- CAS No.
- 119022-51-4
- Chemical Name:
- 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL
- Synonyms
- TIMTEC-BB SBB000154;Pyroxasulfone Impurity 1;1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL;5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-3-OL;2-methyl-3-(trifluoromethyl)-1H-pyrazol-5-one;3-HYDROXY-1-METHYL-5-(TRIFLUOROMETHYL)PYRAZOLE;3-HYDROXY-1-METHYL-5-TRIFLUOROMETHYL-1H-PYRAZOLE;5-HYDROXY-2-METHYL-3-TRIFLUOROMETHYL-1H-PYRAZOLE;1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-ol,99+%;3-Hydroxy-1-methyl-5-(trifluoromethyl)pyrazole97%
- CBNumber:
- CB1256895
- Molecular Formula:
- C5H5F3N2O
- Molecular Weight:
- 166.1
- MDL Number:
- MFCD00085094
- MOL File:
- 119022-51-4.mol
| Product description | Number | Pack Size | Price |
| 3-Hydroxy-1-methyl-5-(trifluoromethyl)pyrazole 98% | CAPOD11112 | 1g | $19 |
| 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-ol | 010737 | 1g | $98 |
| 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-ol >95% | 044751 | 500mg | $118 |
| 3-Hydroxy-1-methyl-5-(trifluoromethyl)pyrazole 97% | PC4858 | 5g | $127 |
| 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-ol >95% | 044751 | 1g | $151 |
| More product size | |||
| Melting point | 114-115 °C |
|---|---|
| Density | 1.3876 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 7.35±0.70(Predicted) |
| Appearance | White to yellow Solid |
| BRN | 3543409 |
| CAS DataBase Reference | 119022-51-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P301+P310-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,T | |||||||||
| Risk Statements | 36/37/38-25 | |||||||||
| Safety Statements | 24/25-45-26 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933199090 | |||||||||
| NFPA 704 |
|
1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Frontier Specialty Chemicals | CAPOD11112 | 3-Hydroxy-1-methyl-5-(trifluoromethyl)pyrazole 98% | 119022-51-4 | 1g | $19 | 2021-12-16 | Buy |
| Oakwood | 010737 | 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-ol | 119022-51-4 | 1g | $98 | 2021-12-16 | Buy |
| Matrix Scientific | 044751 | 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-ol >95% | 119022-51-4 | 500mg | $118 | 2021-12-16 | Buy |
| Apolloscientific | PC4858 | 3-Hydroxy-1-methyl-5-(trifluoromethyl)pyrazole 97% | 119022-51-4 | 5g | $127 | 2021-12-16 | Buy |
| Matrix Scientific | 044751 | 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-ol >95% | 119022-51-4 | 1g | $151 | 2021-12-16 | Buy |
1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL Chemical Properties,Uses,Production
Chemical Properties
White to yellow or pink crystalline powder
Definition
ChEBI: 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-ol is a member of pyrazoles.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 27, p. 243, 1990 DOI: 10.1002/jhet.5570270224
Synthesis
372-31-6
60-34-4
119022-51-4
The general procedure for the synthesis of 1-methyl-5-(trifluoromethyl)-1H-pyrazol-3(2H)-one from ethyl trifluoroacetoacetate and methylhydrazine was as follows: 6 kg of ethyl ether and 6164.2 g (33.5 mol) of ethyl trifluoroacetoacetate were added to a reaction flask. Under continuous stirring, 1542.4 g (33.5 mol) of methylhydrazine was slowly added and the temperature was maintained at about 24 °C during the reaction. After continued stirring for 1 hour, the reaction was confirmed to be complete. Subsequently, most of the ether solvent was removed by vapor extraction and the residue was slurried in 12 L of chloroform. To the slurried mixture was added 50 mL of concentrated sulfuric acid with continuous stirring overnight. Next, another 100 mL of sulfuric acid was added, and the slurry was washed once with 3 L of water, followed by five washes with 3 L of 10% sodium bicarbonate solution to remove the 5-hydroxy isomer, and finally two washes with 3 L of water. The aqueous layer and undissolved crystals were sequentially extracted twice with 4 L of chloroform. The chloroform layers were combined and concentrated under reduced pressure on a rotary evaporator at 40 °C to give 1405.9 g (25.3% yield) of the target product with a melting point of 205 °C (literature value 130°-131 °C).
References
[1] Patent: US4855442, 1989, A
1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16516 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29799 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5661 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15142 | 58 |
View Lastest Price from 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-10-13 | 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3(2H)-one
119022-51-4
|
US $1.60-9.60 / kg | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2021-08-12 | 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL
119022-51-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-12-26 | 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL
119022-51-4
|
US $1.00 / KG | 1KG | 99% | 600kg | Career Henan Chemical Co |
-
- 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3(2H)-one
119022-51-4
- US $1.60-9.60 / kg
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL
119022-51-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL
119022-51-4
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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