Nodinitib-1
- CAS No.
- 799264-47-4
- Chemical Name:
- Nodinitib-1
- Synonyms
- ML 130;Nodinitib-1;Noditinib-1;CID-1088438;Noditiniβ-1;ML-130;ML 130;130 (Nodinitib-1);ML130;CID-1088438;Nodinitib-1 ，S2863;ML130 (Nodinitib-1)
- CBNumber:
- CB12591864
- Molecular Formula:
- C14H13N3O2S
- Molecular Weight:
- 287.34
- MDL Number:
- MFCD04322367
- MOL File:
- 799264-47-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Nodinitib-1 ≥98% (HPLC) | SML0379 | 5mg | $146 |
| Nodinitib-1 ≥98% (HPLC) | SML0379 | 25mg | $538 |
| Nodinitib-1 ≥95% | 11040 | 5mg | $49 |
| Nodinitib-1 ≥95% | 11040 | 10mg | $93 |
| Nodinitib-1 ≥95% | 11040 | 25mg | $213 |
| More product size | |||
| Melting point | 191-192 °C (decomp) |
|---|---|
| Boiling point | 532.5±43.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO: >10mg/mL |
| pka | 2.55±0.10(Predicted) |
| form | powder |
| color | white to beige |
| InChI | 1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16) |
| InChIKey | SRFABRWQVPCPRG-UHFFFAOYSA-N |
| SMILES | NC1=NC2=C(N1S(C3=CC=C(C)C=C3)(=O)=O)C=CC=C2 |
| UNSPSC Code | 51111800 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Nodinitib-1 price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0379 | Nodinitib-1 ≥98% (HPLC) | 799264-47-4 | 5mg | $146 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML0379 | Nodinitib-1 ≥98% (HPLC) | 799264-47-4 | 25mg | $538 | 2025-07-31 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 799264-47-4 | 5mg | $49 | 2026-04-30 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 799264-47-4 | 10mg | $93 | 2026-04-30 | Buy |
| Cayman Chemical | 11040 | Nodinitib-1 ≥95% | 799264-47-4 | 25mg | $213 | 2026-04-30 | Buy |
Nodinitib-1 Chemical Properties,Uses,Production
Uses
Noditinib-1 is a potent and selective inhibitor of NOD1-induced NF-κB activation. Mutations in NOD proteins have been associated with various inflammatory diseases and Noditinib-1 shows promise as a potential therapeutic agent.
Definition
ChEBI: 1-(4-methylphenyl)sulfonyl-2-benzimidazolamine is a sulfonamide.
Biological Activity
Nodinitib-1 (ML130) is a selectiove inhibitor of of the nucleotide oligomerization domain (NOD)-1 receptor, which is involved in innate immune response and has been associated with several inflammatory diseases. NOD1 and NOD2 recognize distinct structures derived from bacterial peptidoglycans and directly activate NF-B pathway, which controls the production of proinflammatory molecules. Nodinitib-1 has 40:1 selectivity for NOD1 over NOD2.
IC 50
NOD1
Nodinitib-1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 | contact@trustwe.com | China | 5742 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11674 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 54746 | 58 |
View Lastest Price from Nodinitib-1 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Nodinitib-1
799264-47-4
|
$50.00-143.00 | 99.97% | 10g | TargetMol Chemicals Inc. | ||
 |
2019-12-24 | Nodinitib-1
799264-47-4
|
$1.00 | 1g | 99% | 20kg | Career Henan Chemical Co |
-
- Nodinitib-1
799264-47-4
- $50.00-143.00
- 99.97%
- TargetMol Chemicals Inc.
-
- Nodinitib-1
799264-47-4
- $1.00
- 99%
- Career Henan Chemical Co
