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ChemicalBook >> CAS DataBase List >>(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Structure
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride structure
CAS No.
874460-46-5
Chemical Name:
(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride
Synonyms
Aprepitant Impurity SM3QF;Aprepitant Impurity 7 HCl;Aprepitant Impurity 3 HCl;Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride;(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride;(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride;(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride (Aprepitant Impurity)
CBNumber:
CB12669002
Molecular Formula:
C20H20ClF6NO2
Molecular Weight:
455.83
MDL Number:
MOL File:
874460-46-5.mol
Last updated:2024-06-11 19:18:13
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(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Chemical Properties,Uses,Production

Uses

Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1''S)-Aprepitant Hydrochloride is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		16314854226; +16314854226 inquiry@bocsci.com United States 19853 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		+8618627948422 sale@hdimpurity.com China 3681 58
Shanghai Ranxon Chemical Co., Ltd. 13148101715 2073632910@qq.com China 38 55
Nanjing XiZe Biotechnology CO., Ltd. 025-66023220 15250997978 1511893459@qq.com China 4849 55
BOC Sciences 16314854226 info@bocsci.com United States 9923 65
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9926 55
Jinan blalong chemical co. LTD 2710913286@.com 1513643261@qq.com China 14246 58
Cato Research Chemicals Inc. +86-020-81960175-877 4000-868-328 tianwen.zhan@cato-chem.com United States 10404 58
Hubei Xinyang Medical Technology Co., Ltd 15347293736 2853117764@yongstandards.com China 9988 58
Guangzhou Juntang Technology Co., Ltd 020-36607679 13502246435 sales@dmstandards.com China 10945 58
Supplier Advantage
BOC Sciences 		58
ShenZhen H&D Pharmaceutical Technology Co., LTD 		58
Shanghai Ranxon Chemical Co., Ltd. 55
Nanjing XiZe Biotechnology CO., Ltd. 55
BOC Sciences 65
Hubei Yangxin Medical Technology Co., Ltd. 55
Jinan blalong chemical co. LTD 58
Cato Research Chemicals Inc. 58
Hubei Xinyang Medical Technology Co., Ltd 58
Guangzhou Juntang Technology Co., Ltd 58

View Lastest Price from (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Aprepitant Impurity 36 pictures 2026-03-12 Aprepitant Impurity 36
874460-46-5
 10mg 98% 500mg ShenZhen H&D Pharmaceutical Technology Co., LTD

874460-46-5((2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride)Related Search:

Aprepitant 5-[[(2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Fosaprepitant Benzyl dihydrogen phosphate
(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine (2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Fosaprepitant Benzyl Ester (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine hydrochloride
ent-Aprepitant 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one (R,R,R)-Aprepitant (1S,2S,3R)-Aprepitant Aprepitant
Defluoro Aprepitant Aprepitant Impurity B HCl Aprepitant Impurity 11 HCl

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(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine hydrochloride Aprepitant Impurity 7 HCl Aprepitant Impurity SM3QF Des-(4-fluoro-1,2,4-triazol-3-one-5-methyl (2R,3S,1'S)-Aprepitant Hydrochloride Aprepitant Impurity 3 HCl (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride (Aprepitant Impurity) (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride 874460-46-5