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ChemicalBook >> CAS DataBase List >>4-AMino-5-iodopyrrolo[2,3-d]pyriMidine

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Structure
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine structure
CAS No.
163622-50-2
Chemical Name:
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine
Synonyms
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine;5-iodo-1H-pyrrolo[2,3-d]pyrimidin-4-amine;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-;5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
CBNumber:
CB12704376
Molecular Formula:
C6H5IN4
Molecular Weight:
260.04
MDL Number:
MFCD13619882
MOL File:
163622-50-2.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:43
Request For Quotation

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Properties

Boiling point 254.0±50.0 °C(Predicted)
Density 2.58±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 11.57±0.20(Predicted)
Appearance Off-white to light brown Solid
InChI InChI=1S/C6H5IN4/c7-3-1-9-6-4(3)5(8)10-2-11-6/h1-2H,(H3,8,9,10,11)
InChIKey KLKWCKQHBCUTCL-UHFFFAOYSA-N
SMILES C1=NC(N)=C2C(I)=CNC2=N1
CAS DataBase Reference 163622-50-2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312-P305+P351+P338
HS Code  2933998090

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical I1161 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine 163622-50-2 1G $83 2025-07-31 Buy
TCI Chemical I1161 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine 163622-50-2 5G $248 2025-07-31 Buy
TRC I737268 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine 163622-50-2 50mg $45 2021-12-16 Buy
AK Scientific AMTH139 5-Iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine 163622-50-2 10g $280 2021-12-16 Buy
SynQuest Laboratories 3H30-H-05 4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidine 163622-50-2 1g $135 2021-12-16 Buy
Product number Packaging Price Buy
I1161 1G $83 Buy
I1161 5G $248 Buy
I737268 50mg $45 Buy
AMTH139 10g $280 Buy
3H30-H-05 1g $135 Buy

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Chemical Properties,Uses,Production

Synthesis

4-Amino-7H-pyrrolo[2,3-d]pyrimidine

1500-85-2

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine

163622-50-2

The general procedure for the synthesis of 5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine using 4-amino-7H-pyrrolo[2,3-d]pyrimidine as starting material was as follows: 7H-pyrrolo[2,3-d]pyrimidin-4-amine (1.3 g, 9.7 mmol, 1.0 eq.) was dissolved in chloroform (45 mL) at room temperature, followed by the addition of N-iodo-substituted butylenedi imide (NIS, 2.18 g, 9.7 mmol, 1.0 equiv). The reaction mixture was heated to reflux for 2 hours. Upon completion of the reaction, the precipitate was collected by filtration and dried under vacuum to afford the target product 5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine (2.09 g, 83% yield) as a white solid.

References

[1] Patent: WO2018/11628, 2018, A1. Location in patent: Paragraph 00303
[2] Patent: CN106831790, 2017, A. Location in patent: Paragraph 0043-0046
[3] Patent: WO2014/184069, 2014, A1. Location in patent: Page/Page column 33; 34
[4] Organic and Biomolecular Chemistry, 2014, vol. 12, # 28, p. 5158 - 5167
[5] Patent: WO2017/161344, 2017, A1. Location in patent: Paragraph 0813; 0820

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Preparation Products And Raw materials

Raw materials

4-Amino-7H-pyrrolo[2,3-d]pyrimidine N-Iodosuccinimide Chloroform

Preparation Products

5-iodo-7-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-aMine

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Suppliers

Global( 82)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29852 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 8497 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Beijing Ribio Biotech Co.,Ltd 		010-62664360 +8613328773880 wucy@ribio.com.cn China 117 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		+8618795957998 karmelhk@126.com CHINA 2886 58
changzhou huayang technology co., ltd 		+8615250961469 2571773637@qq.com China 9644 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9297 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 market18@leapchem.com China 43339 58
Supplier Advantage
Shanghai Time Chemicals CO., Ltd. 		55
career henan chemical co 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Accela ChemBio Inc. 		58
Beijing Ribio Biotech Co.,Ltd 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
KARMEL TECHNOLOGY (HK) CO.,LIMITED 		58
changzhou huayang technology co., ltd 		58
Henan Aochuang Chemical Co.,Ltd. 		58
HANGZHOU LEAP CHEM CO., LTD. 		58

View Lastest Price from 4-AMino-5-iodopyrrolo[2,3-d]pyriMidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine pictures 2025-04-04 4-AMino-5-iodopyrrolo[2,3-d]pyriMidine
163622-50-2
 US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine pictures 2019-08-09 4-AMino-5-iodopyrrolo[2,3-d]pyriMidine
163622-50-2
 US $8.80 / KG 1KG 97%-99% 100kg Career Henan Chemical Co

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine Spectrum

4-AMino-5-iodopyrrolo[2,3-d]pyriMidine(163622-50-2)1HNMR
4-AMino-5-iodopyrrolo[2,3-d]pyriMidine 5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo- 5-iodo-1H-pyrrolo[2,3-d]pyrimidin-4-amine 163622-50-2