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Uridine 5'-monophosphate

Uridine 5'-monophosphate structure

CAS No.: 58-97-9

Chemical Name:: Uridine 5'-monophosphate

Synonyms: URIDYLIC ACID;((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate;5’-ump;UMP.H2;uridinemonophosphate;Uridine Monophospahte;Uridine 5’-monophosphte;UMP-H;U 5'-P;98-100%

CBNumber:: CB1271654

Molecular Formula:: C9H13N2O9P

Molecular Weight:: 324.18

MDL Number:: MFCD00067346

MOL File:: 58-97-9.mol

Last updated:2025-09-30 18:11:34

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Uridine 5'-monophosphate Properties

Melting point	202°C (rough estimate)
Density	1.865±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	H2O: soluble50mg/mL, clear, colorless
form	solid
pka	pK1:6.63 (25°C)
color	White to Off-White
biological source	natural (organic)
Water Solubility	H2O: soluble 50mg/mL, clear, colorless
InChI	InChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKey	DJJCXFVJDGTHFX-XVFCMESISA-N
SMILES	P(OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1O)(O)(O)=O
CAS DataBase Reference	58-97-9
FDA UNII	E2OU15WN0N
EPA Substance Registry System	5'-Uridylic acid (58-97-9)
UNSPSC Code	41106305
NACRES	NA.51

SAFETY

Risk and Safety Statements

Safety Statements	24/25
WGK Germany	3
RTECS	YU8088000
HS Code	29349990

Uridine 5'-monophosphate price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	U1752	Uridine 5′-monophosphate ≥98%	58-97-9	1g	$215.99	2025-07-31	Buy
TCI Chemical	U0078	Uridine 5'-Monophosphate	58-97-9	5G	$115	2025-07-31	Buy
TCI Chemical	U0078	Uridine 5'-Monophosphate	58-97-9	25G	$345	2025-07-31	Buy
TRC	U830020	Uridine 5′-monophosphate	58-97-9	2.5g	$275	2021-12-16	Buy
Biosynth Carbosynth	NU05691	Uridine 5'-monophosphate	58-97-9	5G	$250	2021-12-16	Buy

Product number	Packaging	Price	Buy
U1752	1g	$215.99	Buy
U0078	5G	$115	Buy
U0078	25G	$345	Buy
U830020	2.5g	$275	Buy
NU05691	5G	$250	Buy

Uridine 5'-monophosphate Chemical Properties,Uses,Production

Description

Uridine 5'-monophosphateis a nucleotide that is synthesized from uridine. Uridine 5'-monophosphate has been shown to have anticancer activity in vitro and in vivo, as well as antiviral activity against herpes viruses. It is also used in foods such as infant formula to as a method of increasing uridine levels in blood.

Chemical Properties

(Uridine-3′-phosphate) Crystallizes in prisms from methanol. Freely soluble in water and alcohol; dextrorotatory in solution.

Uses

Uridine 5'-monophosphate is a nucleotide used as monomer in RNA. It is used in foods such as infant formula to as a method of increasing uridine levels in blood.

Uses

Biochemical research.

Definition

The monophosphoric ester of uracil, i.e., the nucleotide containing uracil-d-ribose and phosphoric acid. The phosphate may be esterified to either the 2, 3, or 5 carbon of ribose, yielding uridine-2′-phosphate, uridine-3′phosphate, and uridine-5′-phosphate, respectively.

Application

Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.

General Description

Uridine 5'-monophosphate acts as a precursor for all pyrimidine nucleotides.

Synthesis

56428-57-0

58-97-9

Uridine, 5'-(hydrogen phosphorofluoridate)

3803-29-0

The general procedure for the synthesis of ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyldihydrophosphoric acid and the compound (CAS: 3803-29-0) from the compound (CAS: 56428-57-0) was carried out as follows: selected activated nucleotides of a 15 mM solution and ImpN (N = A, U, C, G, dA) were dissolved in 1 M sodium fluoride (Sigma). The reaction mixtures were allowed to stand at 24°C for 8-10 days, during which time the progress of the reaction was monitored periodically by HPLC using a reversed-phase column. Upon completion of the reaction, each product mixture contained predominantly the corresponding fluorinated phosphate ester and a small amount of NMP hydrolysis product. Separation was carried out using a semipreparative reversed-phase Alltima C-18, 5 μm (10 mm × 300 mm) column (Alltech, Grace Davison) under isocratic elution conditions (88% aqueous 0.2% formic acid (Sigma) with 12% 30% acetonitrile). The flow rate was set at mL/min. the collected fractions were characterized by mass spectrometry.

References

[1] Tetrahedron Letters, 2014, vol. 55, # 8, p. 1464 - 1466

Uridine 5'-monophosphate synthesis

Synthesis of Uridine 5'-monophosphate from UDP

Uridine 5'-monophosphate Preparation Products And Raw materials

Raw materials

uridine 5'-(phosphoimidazolate) UTP

Preparation Products

Disodium 5'-Inosinate UTP 2',3'-cyclic UMP URIDYLIC ACID UDP

Uridine-5'-triphosphoric acid trisodium salt

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Uridine 5'-monophosphate Suppliers

Global( 371)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)	+86-86-057182358004 +8613588879771	info@weitai-pharmaceutical.com	China	61	58
Hangzhou Meiya Pharmaceutical Co Ltd	+86-021-33686691 +8618001850931	sales@meiyapharm.com	China	58	58
Hebei Chuanghai Biotechnology Co., Ltd	+8617732866630	abby@chuanghaibio.com	China	8773	58
Hebei Mujin Biotechnology Co.,Ltd	+8613288715578	sales@hbmojin.com	China	12248	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21620	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58

Supplier	Advantage
WeiTai BioPharmaceutical Co.,Ltd(Hangzhou?)	58
Hangzhou Meiya Pharmaceutical Co Ltd	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Mujin Biotechnology Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Standardpharm Co. Ltd.	58

View Lastest Price from Uridine 5'-monophosphate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-30	Uridine 5'-monophosphate 58-97-9	US $97.00 / mg		99.95%	10g	TargetMol Chemicals Inc.
2025-09-29	Uridine 5’-monophosphte（UMP-H） 58-97-9	US $0.00-0.00 / kg	1kg	≥98.0%	30 MT	Hangzhou Meiya Pharmaceutical Co Ltd
2025-09-29	Uridine 5′-monophosphate 58-97-9	US $0.00-0.00 / kg	1kg	98%min	500kg	WUHAN FORTUNA CHEMICAL CO., LTD

Uridine 5'-monophosphate
58-97-9
US $97.00 / mg
99.95%
TargetMol Chemicals Inc.

Uridine 5’-monophosphte（UMP-H）
58-97-9
US $0.00-0.00 / kg
≥98.0%
Hangzhou Meiya Pharmaceutical Co Ltd

Uridine 5′-monophosphate
58-97-9
US $0.00-0.00 / kg
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

Uridine 5'-monophosphate Spectrum

UMP(58-97-9)¹³CNMR UMP(58-97-9)IR1

58-97-9(Uridine 5'-monophosphate)Related Search:

Uridine 5′-monophosphate disodium salt 3'-Uridylic acid, disodium salt Uridine UTP URIDINE-13C9, 15N2-5 TRIPHOSPHATE SODI U

DMT-2′O-TBDMS-rU Phosphoramidite UDP Guanosine-5'-diphosphate disodium salt UDPGA TRISODIUM SALT Uridine-5'-triphosphoric acid trisodium salt

UDP-ALPHA-D-GALACTOSE DISODIUM SALT Uridine-5'-diphosphate disodium salt Uridine Diphosphate Choline Uridine Diphosphate Choline Ammonium Salt 2',3',5'-TRI-O-BENZOYLURIDINE

Uridine-5-oxyacetic acid methyl ester Uridine Diphosphate-GlcNaz BPBNNONNJSGJLR-UHFFFAOYSA-L

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U 5'-P URIDINE-5'-PHOSPHATE URIDYLIC ACID 5’-ump ump(nucleicacid) uridine5’-(dihydrogenphosphate) uridine5’-phosphoricacid uridinemonophosphate UMP-H Uridylic acid, 5'-Uridylic acid, Uridine phosphate, 5'-UMP, Uridine 5'-phosphoric acid uridinephosphate uridine 5-monophosphate free acid Uridine Monophospahte Uridine Monophosphate and salts URIDINE-5'-MONOPHOSPHATE FREE ACID 98-100% URIDINE-5'-MONOPHOSPHATE FREE ACID CELL CULTURE REAGENT 98-100% 98-100% Uridine-5''-monophosphoric acid (and/or unspecified salts) URIDINE 5''-MONOPHOSPHATE (UMP) U 5μ-P, UMP, Uridylic acid Urd-5'-P 5'-Uridylic acid (8ci)(9ci) Uridylate Uridine 5′-monophosphate,U 5′-P, UMP, Uridylic acid uridine monophosphate {= UMP} ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphate UMP.H2 [(2R,3S,4R,5R)-5-(2,4-dioxo-1-pyrimidinyl)-3,4-dihydroxy-2-oxolanyl]methyl phosphate Uridine-5'-phosphate/UMP Diquafosol Impurity 1(UMP Sodium Salt) 5'- uridine acid Uridine 5’-monophosphte 5'-UMP·H2 Uridine-5-Monophosphat Uridine 5'-monophosphate(UMP-H) Uridine 5'-monophosphate Solution, 100μg/mL UMP USP/EP/BP 5'-Uridylate monophosphate {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate UMP, Uridine Monophosphate UR, Uridine Monophosphate Uridine 5′-monophosp Uridine 5'-monophosphte(UMP-H) UMP CAS Uridine 5'-monophosphate (UMP-H) Uridine 5'-monophosphate 5'-uridine 5'-Uridylic acid Uridine 5'-monophosphte uridine 3'-(dihydrogen phosphate) Prinomastat Impurity 1 Uridine 5'-monophosphate【U1752】 Uridine 5'-monophosphate 58-97-9 58-97-7 BioChemical Biochemicals and Reagents