Methyl 5-broMo-2-chloro-1,6-dihydro-1-Methyl-6-oxopyridine-3-carboxylate
- CAS No.
- 869357-63-1
- Chemical Name:
- Methyl 5-broMo-2-chloro-1,6-dihydro-1-Methyl-6-oxopyridine-3-carboxylate
- Synonyms
- Methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate;Methyl 5-broMo-2-chloro-1,6-dihydro-1-Methyl-6-oxopyridine-3-carboxylate;Methyl 5-bromo-2-chloro-1,6-dihydro-1-methyl-6-oxo-3-pyridinecarboxylate;3-Pyridinecarboxylic acid, 5-bromo-2-chloro-1,6-dihydro-1-methyl-6-oxo-, methyl ester
- CBNumber:
- CB12736016
- Molecular Formula:
- C8H7BrClNO3
- Molecular Weight:
- 280.5
- MDL Number:
- MFCD26395170
- MOL File:
- 869357-63-1.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
Methyl 5-broMo-2-chloro-1,6-dihydro-1-Methyl-6-oxopyridine-3-carboxylate price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 296527 | Methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate | 869357-63-1 | 100.00mg | $60 | 2026-05-19 | Buy |
| Matrix Scientific | 296527 | Methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate | 869357-63-1 | 250.00mg | $93 | 2026-05-19 | Buy |
| Matrix Scientific | 296527 | Methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate | 869357-63-1 | 1.00g | $241 | 2026-05-19 | Buy |
| Synthonix | M48508 | Methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate 95+% | 869357-63-1 | 100mg | $52 | 2026-05-06 | Buy |
| Synthonix | M48508 | Methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate 95+% | 869357-63-1 | 250mg | $100 | 2026-05-06 | Buy |
Methyl 5-broMo-2-chloro-1,6-dihydro-1-Methyl-6-oxopyridine-3-carboxylate Chemical Properties, Uses, Production
Synthesis
853109-24-7
869357-63-1
General procedure for the synthesis of methyl 5-bromo-2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate from methyl 2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate: to methyl 2-chloro-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate (0.100 g, 0.496 mmol) in dimethylformamide ( DMF, 5 mL) solution was added N-bromosuccinimide (NBS, 0.177 g, 0.992 mmol). The reaction mixture was stirred at room temperature in a nitrogen (N2) atmosphere for 4 hours. Upon completion of the reaction, the reaction was quenched with saturated sodium bisulfite solution and subsequently diluted and layered with ethyl acetate (EtOAc) and water (H2O). The aqueous layer was back-extracted with ethyl acetate (2×). The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give a yellow solid product in quantitative yield.
References
[1] Patent: WO2007/44084, 2007, A2. Location in patent: Page/Page column 77
[2] Patent: WO2008/120004, 2008, A1. Location in patent: Page/Page column 23
[3] Patent: WO2008/125820, 2008, A1. Location in patent: Page/Page column 33
[4] Patent: WO2010/108652, 2010, A1. Location in patent: Page/Page column 97
[5] Patent: US2005/256123, 2005, A1
Methyl 5-broMo-2-chloro-1,6-dihydro-1-Methyl-6-oxopyridine-3-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 5-broMo-2-chloro-1,6-dihydro-1-Methyl-6-oxopyridine-3-carboxylate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai ChuangYan Chemical Technology Co., Ltd. | 021-11111111 11111111111 | 546919421@qq.com | China | 3769 | 55 |
| Xi'an NewProChem Co.,Ltd. | 15332490153 | newprochem@126.com | China | 991 | 55 |
| Aikon International Limited | 025-58851090 13913916777 | sales01@aikonchem.com | China | 15947 | 58 |
| Shandong utilizing biological technology co., LTD | 18669728830 15966937598 | 3407650895@qq.com | China | 5185 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44871 | 58 |
| Shanghai Sunway Pharmaceutical Technology Co.,Ltd. | 13611835272 13611835272 | mmwang@sunwaypharm.com | China | 44090 | 58 |
| PharmaBlock Sciences (Nanjing), Inc. | 4000255188 | sales_china@pharmablock.com | China | 9999 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59929 | 58 |
| Bide Pharmatech Ltd. | 400-6005915 | sales@picasso-e.com | China | 39645 | 58 |
| Henan Weitixi Chemical Technology Co., Ltd | 0371-53370800 18037197114 | 3807961510@qq.com | China | 9977 | 58 |
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