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6-NITROIMIDAZO[1,2-A]PYRIDINE

6-NITROIMIDAZO[1,2-A]PYRIDINE Structure
6-NITROIMIDAZO[1,2-A]PYRIDINE structure
CAS No.
25045-82-3
Chemical Name:
6-NITROIMIDAZO[1,2-A]PYRIDINE
Synonyms
6-NITROIMIDAZO[1,2-A]PYRIDINE;6-nitrosoimidazo[1,2-a]pyridine;IMidazo[1,2-a]pyridine, 6-nitro-
CBNumber:
CB1278345
Molecular Formula:
C7H5N3O2
Molecular Weight:
163.13
MDL Number:
MFCD05863333
MOL File:
25045-82-3.mol
Last updated:2025-07-24 18:13:45
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6-NITROIMIDAZO[1,2-A]PYRIDINE Properties

Melting point 229-231°
Density 1.49±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 3.70±0.50(Predicted)
Appearance Yellow to brown Solid
InChI InChI=1S/C7H5N3O2/c11-10(12)6-1-2-7-8-3-4-9(7)5-6/h1-5H
InChIKey RXZZQEFTZIHXRI-UHFFFAOYSA-N
SMILES C12=NC=CN1C=C([N+]([O-])=O)C=C2
CAS DataBase Reference 25045-82-3

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
HazardClass  IRRITANT
HS Code  2933399990

6-NITROIMIDAZO[1,2-A]PYRIDINE price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 045755 6-Nitroimidazo[1,2-a]pyridine 95+% 25045-82-3 5g $60 2021-12-16 Buy
AK Scientific Z4497 6-Nitroimidazo[1,2-a]pyridine 25045-82-3 1g $70 2021-12-16 Buy
Matrix Scientific 045755 6-Nitroimidazo[1,2-a]pyridine 95+% 25045-82-3 25g $150 2021-12-16 Buy
BroadPharm BP-20256 6-nitro-imidazo[1,2-a]pyridine 96% 25045-82-3 5G $290 2021-12-16 Buy
Matrix Scientific 188692 6-NitroH-imidazo[1,2-a]pyridine 25045-82-3 10g $298 2021-12-16 Buy
Product number Packaging Price Buy
045755 5g $60 Buy
Z4497 1g $70 Buy
045755 25g $150 Buy
BP-20256 5G $290 Buy
188692 10g $298 Buy

6-NITROIMIDAZO[1,2-A]PYRIDINE Chemical Properties,Uses,Production

Synthesis

2-Amino-5-nitropyridine

4214-76-0

Bromoacetaldehyde diethyl acetal

2032-35-1

6-NITROIMIDAZO[1,2-A]PYRIDINE

25045-82-3

In a 250 mL single-neck flask, bromoacetaldehyde diethyl acetal (42.5 g, 215.7 mmol) was dissolved in a mixture of 1 mol/L hydrochloric acid (120 mL) and ethanol (20 mL) and stirred at room temperature for 30 minutes. It was then heated to reflux and stirred continuously until the solution became clear. Upon completion of the reaction, the solution was cooled to room temperature and the pH was adjusted to near neutral with sodium bicarbonate solution. 2-Amino-5-nitropyridine (15.0 g, 107.8 mmol) was added and the reaction was stirred overnight at room temperature. At the end of the reaction, extraction was carried out with ethyl acetate (100 mL×3), the organic phases were combined, and the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography (eluent ratio: petroleum ether:ethyl acetate = 2:1) to afford 13.7 g of yellow-brown crystalline 6-nitroimidazo[1,2-a]pyridine in 77.6% yield.

References

[1] Patent: CN107129496, 2017, A. Location in patent: Paragraph 0026-0028; 0014-0016; 0020-0022

6-NITROIMIDAZO[1,2-A]PYRIDINE synthesis

4214-76-0
2032-35-1
25045-82-3
Synthesis of 6-NITROIMIDAZO[1,2-A]PYRIDINE from 2-Amino-5-nitropyridine and Bromoacetaldehyde diethyl acetal

6-NITROIMIDAZO[1,2-A]PYRIDINE Preparation Products And Raw materials

Raw materials

2-Amino-5-nitropyridine Hydrochloric acid Ethanol Bromoacetaldehyde diethyl acetal

Preparation Products

6-NITROIMIDAZO[1,2-A]PYRIDINE Suppliers

Global( 96)Suppliers
Supplier Tel Email Country ProdList Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29800 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10035 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
LEAP CHEM CO., LTD. 		+86-852-30606658 19957148339; market18@leapchem.com China 24727 58
PT CHEM GROUP LIMITED 		+86-85511178; peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49977 58
Supplier Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
58
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Fuxin Pharmaceutical 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
LEAP CHEM CO., LTD. 		58
PT CHEM GROUP LIMITED 		58
GIHI CHEMICALS CO.,LIMITED 		58

View Lastest Price from 6-NITROIMIDAZO[1,2-A]PYRIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-NITROIMIDAZO[1,2-A]PYRIDINE pictures 2019-12-26 6-NITROIMIDAZO[1,2-A]PYRIDINE
25045-82-3
 US $1.00 / KG 1KG 99% 100KG Career Henan Chemical Co

6-NITROIMIDAZO[1,2-A]PYRIDINE Spectrum

6-NITROIMIDAZO[1,2-A]PYRIDINE(25045-82-3)1HNMR

25045-82-3(6-NITROIMIDAZO[1,2-A]PYRIDINE)Related Search:

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2-BENZO[1,3]DIOXOL-5-YL-3-BROMO-6-NITRO-IMIDAZO[1,2-A]PYRIDINE [4-(2,7-DIMETHYL-6-NITRO-IMIDAZO[1,2-A]PYRIDIN-3-YL)-THIAZOL-2-YL]-HYDRAZINE (6-NITROIMIDAZO[1,2-A]PYRIDIN-8-YL)(PHENYL)METHANONE

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6-NITROIMIDAZO[1,2-A]PYRIDINE IMidazo[1,2-a]pyridine, 6-nitro- 6-nitrosoimidazo[1,2-a]pyridine 25045-82-3