2-Fluoro-4-iodoaniline
- CAS No.
- 29632-74-4
- Chemical Name:
- 2-Fluoro-4-iodoaniline
- Synonyms
- uoro-4-iodoaniL;2-Fluor-4-Iodanilin;2-fluo-4-iodoaniline;2-Fluoro-4-iodoanili;2-fluro-4-iodoaniline;2-FLUORO-4-IODOANILINE;4-iodo-2-fluoroaniline;2-Fluoro-4-idioaniline;4-iodo-o-fluoroaniline;2-FLORO 4-IODO ANILINE
- CBNumber:
- CB1281329
- Molecular Formula:
- C6H5FIN
- Molecular Weight:
- 237.01
- MDL Number:
- MFCD00011738
- MOL File:
- 29632-74-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Fluoro-4-iodoaniline >98.0%(GC) | F0417 | 5g | $37 |
| 2-Fluoro-4-iodoaniline >98.0%(GC) | F0417 | 25g | $62 |
| 2-Fluoro-4-iodoaniline | F591985 | 50g | $100 |
| 2-Fluoro-4-iodoaniline | F591985 | 25g | $50 |
| 2-Fluoro-4-iodoaniline | J93927 | 100g | $55 |
| More product size | |||
| Melting point | 55-57 °C (lit.) |
|---|---|
| Boiling point | 248.6±25.0 °C(Predicted) |
| Density | 2.008±0.06 g/cm3(Predicted) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 2.41±0.10(Predicted) |
| form | Powder |
| color | Off-white to brown |
| Water Solubility | insoluble |
| Sensitive | Light Sensitive |
| BRN | 2081100 |
| InChIKey | CUMTUBVTKOYYOU-UHFFFAOYSA-N |
| LogP | 2.680 (est) |
| CAS DataBase Reference | 29632-74-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H301-H335 | |||||||||
| Precautionary statements | P280a-P301+P310a-P305+P351+P338-P405-P501a-P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501 | |||||||||
| Hazard Codes | Xi,T,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-37/39-26/37/39 | |||||||||
| RIDADR | PG3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Toxic | |||||||||
| HazardClass | IRRITANT-HARMFUL, LIGHT SENSITIVE | |||||||||
| HS Code | 29214200 | |||||||||
| NFPA 704 |
|
2-Fluoro-4-iodoaniline price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0417 | 2-Fluoro-4-iodoaniline >98.0%(GC) | 29632-74-4 | 5g | $37 | 2026-03-19 | Buy |
| TCI Chemical | F0417 | 2-Fluoro-4-iodoaniline >98.0%(GC) | 29632-74-4 | 25g | $62 | 2026-03-19 | Buy |
| TRC | F591985 | 2-Fluoro-4-iodoaniline | 29632-74-4 | 50g | $100 | 2021-12-16 | Buy |
| TRC | F591985 | 2-Fluoro-4-iodoaniline | 29632-74-4 | 25g | $50 | 2021-12-16 | Buy |
| AK Scientific | J93927 | 2-Fluoro-4-iodoaniline | 29632-74-4 | 100g | $55 | 2021-12-16 | Buy |
2-Fluoro-4-iodoaniline Chemical Properties,Uses,Production
Chemical Properties
off-white to brown powder
Uses
2-Fluoro-4-iodoaniline is widely used in the pharmaceutical, chemical and food industries as a fundamental building block to create a variety of important compounds.
General Description
The profiling of iodine-containing metabolites produced by the earthworm Eisenia veneta by exposing it to 2-fluoro-4-iodoaniline was carried out using high-performance liquid chromatography/inductively coupled plasma mass spectrometry (HPLC/ICPMS).
Synthesis
348-54-9
29632-74-4
The general procedure for the synthesis of 2-fluoro-4-iodoaniline from o-fluoroaniline is as follows: o-fluoroaniline (54 g, 486 mmol) was added to an aqueous solution (250 mL) of sodium bicarbonate (41 g, 486 mmol) with vigorous stirring. The suspension was heated to 60 °C in an oil bath and iodine (123 g, 486 mmol) was added in batches. After addition, the dark-colored mixture was continued to be stirred at 60°C for 3 hours. After completion of the reaction, it was cooled to room temperature and dichloromethane (300 mL) was added, followed by saturated sodium bisulfite solution (300 mL). The two-phase system was stirred vigorously for 10 minutes. The mixture was transferred to a 2L separatory funnel and the organic layer was separated. The aqueous layer was further extracted with dichloromethane (3 x 200 mL) and the combined organic phases were washed with brine (200 mL) and dried over anhydrous sodium sulfate. After filtration, the solvent was removed under reduced pressure to give a black crystalline solid. Hexane (300 mL) was added to the solid and the mixture was heated to reflux. A hexane solution was poured from the black insoluble syrup. Upon cooling, the product crystallized from hexane as fine yellow needles. Final isolation afforded 65 g (274 mmol) of 2-fluoro-4-iodoaniline as a fine yellow solid in 56% yield with a melting point of 53°C. 1H NMR (400 MHz, CDCl3) δ 8.1 (t, J=8Hz, 1H), 7.4 (d, J=6Hz, 1H), 7.2 (d, J=6Hz, 1H).
References
[1] Journal of the Chemical Society. Perkin Transactions 2, 1999, # 3, p. 481 - 491
[2] Arzneimittel-Forschung/Drug Research, 1984, vol. 34, # 11 A, p. 1612 - 1624
[3] Journal of Organic Chemistry, 2005, vol. 70, # 7, p. 2870 - 2873
[4] Patent: WO2004/41793, 2004, A1. Location in patent: Page 141
[5] Chemical Communications, 2014, vol. 50, # 17, p. 2136 - 2138
2-Fluoro-4-iodoaniline Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Hefei Lbao Physical & Chemical Science Co.,Ltd | +15184799099 | lbaochemicals@gmail.com | China | 671 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13815 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 810 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21592 | 55 |
View Lastest Price from 2-Fluoro-4-iodoaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | 2-Fluoro-4-iodoaniline
29632-74-4
|
US $0.00 / kg | 1kg | 98% | Customise | Hefei Lbao Physical & Chemical Science Co.,Ltd | |
 |
2026-03-20 | 2-Fluoro-4-iodoaniline
29632-74-4
|
US $10.00-8.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-12-01 | 2-Fluoro-4-iodoaniline
29632-74-4
|
US $0.00-0.00 / KG | 1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 2-Fluoro-4-iodoaniline
29632-74-4
- US $0.00 / kg
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-
- 2-Fluoro-4-iodoaniline
29632-74-4
- US $10.00-8.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-Fluoro-4-iodoaniline
29632-74-4
- US $0.00-0.00 / KG
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
