Oxalic acid dihydrate
- CAS No.
- 6153-56-6
- Chemical Name:
- Oxalic acid dihydrate
- Synonyms
- ETHANEDIOIC ACID;Oxalate Acid;OXALIC ACID 2HYD XTL;Has two acid;OxalicAcidGr;OXALIC ACID 2H2O;OXALIC ACID PURE;ACS， 99.5-102.5%;Ethanedionic acid;ic acid dihydrate
- CBNumber:
- CB1303757
- Molecular Formula:
- C2H6O6
- Molecular Weight:
- 126.07
- MDL Number:
- MFCD00149102
- MOL File:
- 6153-56-6.mol
- MSDS File:
- SDS
| Melting point | 104-106 °C(lit.) |
|---|---|
| Boiling point | 108-109°C |
| Density | 1,65 g/cm3 |
| bulk density | 813kg/m3 |
| vapor density | 4.4 (vs air) |
| vapor pressure | <0.01 mm Hg ( 20 °C) |
| Flash point | 157°C |
| storage temp. | Store at +5°C to +30°C. |
| solubility | H2O: soluble1M at 20°C, clear, colorless |
| form | Powder/Solid |
| Specific Gravity | 1.65 |
| color | Yellow to yellow-green |
| PH | ~1.0 (25℃, 1M in H2O) |
| PH Range | 6 - 8 at 25 °C |
| Water Solubility | 138 g/L (20 ºC) |
| Sublimation | 157 ºC |
| Merck | 14,6911 |
| BRN | 3679436 |
| Exposure limits | TLV-TWA for anhydrous acid 1 mg/m3 (ACGIH, MSHA, and OSHA); TLV-STEL 2 mg/m3 (ACGIH). |
| Stability | Stable. Incompatible with bases, acid chlorides, steel, silver, silver compounds, moisture. Avoid contact with metals. |
| InChIKey | GEVPUGOOGXGPIO-UHFFFAOYSA-N |
| CAS DataBase Reference | 6153-56-6(CAS DataBase Reference) |
| FDA UNII | 0K2L2IJ59O |
| NIST Chemistry Reference | Oxalic acid dihydrate(6153-56-6) |
| EPA Substance Registry System | Oxalic acid dihydrate (6153-56-6) |
| Absorption | cut-off at 303nm in H2O at 1M |
| UNSPSC Code | 41116107 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302+H312-H318 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352+P312-P305+P351+P338 | |||||||||
| Hazard Codes | Xn,C | |||||||||
| Risk Statements | 21/22-41 | |||||||||
| Safety Statements | 24/25-39-37-36-26 | |||||||||
| RIDADR | UN 3261 8/PG 3 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | RO2450000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29171100 | |||||||||
| Toxicity | LD50 orally in Rabbit: 375 mg/kg | |||||||||
| NFPA 704 |
|
Oxalic acid dihydrate price More Price(76)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2545 | Oxaliplatin Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material | 6153-56-6 | 200MG | $301.15 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.18242 | Oxalic acid dihydrate for synthesis | 6153-56-6 | 100g | $47.2 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.18242 | Oxalic acid dihydrate for synthesis | 6153-56-6 | 1kg | $127 | 2025-07-31 | Buy |
| Sigma-Aldrich | 8.18242 | Oxalic acid dihydrate for synthesis | 6153-56-6 | 25kg | $375 | 2025-07-31 | Buy |
| Sigma-Aldrich | 247537 | Oxalic acid dihydrate ACS reagent, ≥99% | 6153-56-6 | 2.5kg | $361 | 2025-07-31 | Buy |
Oxalic acid dihydrate Chemical Properties,Uses,Production
Chemical Properties
white crystals
Uses
Oxalic acid dihydrate is a purifying agent in pharmaceutical industry, special in antibiotic medication, such as Oxytetracycline , Chloramphenicol , etc; * Precipitating agent in Rare-earth mineral processing; * Bleaching agent in the textile activities, wood pulp bleaching; * Rust-remover for Metal treatment; * Grinding agent, such as Marble polishing; * Waste water treatment, removing calcium from water.
Uses
A diprotic reducing agent used as a buffer.
Uses
Oxalic acid occurs in the cell sap of Oxalisand Rumex species of plants as the potassium and calcium salt. It is the metabolicproduct of many molds (Merck 1989). Thereare a large number of applications of thiscompound, including indigo dyeing; calicoprinting; removal of paint, rust, and inkstains; metal polishing; bleaching leather; inpesticide compositions and manufacture ofoxalates. It is also used as an analyticalreagent and as a reducing agent in organicsynthesis.
Addition of oxalic acid to chromic acid forthe anodizing of Al alloy has been reported tomodify the morphology and improve the corrosion performance of anodic films (Moutarlier et al. 2004). Also, it is a very effectiveadditive for the ozone treatment of cellulose.It prevents the degradation of cellulose fromozone bleaching.
Definition
Oxalic acid dihydrate (OAD) which has very high initial phase transition enthalpy is a promising phase change material (PCM). This compound is low manufacturing cost and wide usage. In OAD, alternating acid and water molecules that act both as hydrogen-bond donors and acceptors. OAD needs a lot of energy to break the hydrogen-bond in the melting process. Therefore, OAD has a very high heat of fusion of 370 J·g-1,which is a very promising PCM in TES for applications such as industrial waste heat recovery or solar energy storage systems[1].
General Description
Oxalic acid dihydrate (OAD) crystals are reported to be monoclinic with P21/n space group. The electron density of OAD has been obtained using X-ray diffraction studies under high resolution.
Reactivity Profile
At high temperatures oxalic acid decomposes, producing toxic carbon monoxide, andformic acid. Mixing with warm sulfuric acidmay produce the same products: CO2, CO,and formic acid. It reacts with many silvercompounds, forming explosive silver oxalate(NFPA 1986). An explosion occurred whenwater was added to an oxalic acid/sodiumchlorite mixture in a stainless steel beaker.There was also evolution of highly toxicchlorine dioxide gas (MCA 1962). Oxalicacid reacts violently with strong oxidizingsubstances.
Health Hazard
Oxalic acid is a strong poison. The toxicsymptoms from ingestion include vomiting, diarrhea, and severe gastrointestinaldisorder, renal damage, shock, convulsions,and coma. Death may result from cardiovascular collapse. The toxicity arises asoxalic acid reacts with calcium in the tissuesto form calcium oxalate, thereby upsettingthe calcium/potassium ratio (ACGIH 1986).Deposition of oxalates in the kidney tubulesmay result in kidney damage (Hodgson et al.1988).
Oxalic acid may be absorbed into the bodythrough skin contact. It is corrosive to theskin and eyes, producing burns. Dilute solutions of 10% strength may be a mild irritantto human skin. However, the inhalation toxicity is low because of its low vapor pressure.Airborne dusts can produce eyeburn and irritation of the respiratory tract.
LD50 value, oral (rats): 375 mg/kg.
Synthesis
62-76-0
6153-56-6
General procedure for the synthesis of oxalic acid dihydrate from sodium oxalate: Example 1; Using an excess of HCl; 105.0 g of deionized water was added to a glass reactor. Subsequently, 100.0 g of 37% hydrochloric acid and 33.5 g of Aldrich sodium oxalate were added to the reactor. The molar ratio of hydrochloric acid to sodium oxalate was 4:1 and the molar ratio of water to sodium oxalate was 37.3:1. The mixture was placed on a hot plate at 80°C with continuous stirring for 60 minutes until a colorless, clear solution was formed and the solid was completely dissolved. Upon completion of the reaction, the reactor was transferred to an ice bath and cooled until both the internal and external temperatures were reduced to 2 °C. At this point, a white solid was precipitated from the solution. The solids were filtered using a 500 mL cellulose acetate filter funnel with a pore size of 0.45 µm. The solid was washed twice with saturated aqueous oxalic acid solution (about 50 mL each time), and the total mass of the colorless filtrate collected was 188.5 g. The solid was then washed with saturated aqueous oxalic acid solution. The solid was dried in a vacuum oven at 75°C overnight. It was confirmed by X-ray diffraction analysis (using a PANalytical X'PERT Model 3040 Automated Powder Diffractometer, Natick, MA) that the solid contained 17.8 g of oxalic acid dihydrate mixed with anhydrous oxalic acid, where the absence of crystals was an artifact of the drying process. Figure 5 illustrates the X-ray diffraction pattern of the isolated solid. Accordingly, the yield of oxalic acid dihydrate was calculated to be between 56% and 79%. Example 2; Using an insufficient amount of HCl; 130.0 g of deionized water was added to a glass reactor. Subsequently, 75.0 g of 37% hydrochloric acid and 33.5 g of Aldrich sodium oxalate were added to the reactor. The molar ratio of hydrochloric acid to sodium oxalate was 3:1 and the molar ratio of water to sodium oxalate was 39.4:1. The mixture was placed on a hot plate at 80 °C with continuous stirring for 60 minutes until a colorless, clear solution was formed and the solid was completely dissolved. Upon completion of the reaction, the reactor was transferred to an ice bath and cooled until both the internal and external temperatures were reduced to 2 °C. At this point, a white solid was precipitated from the solution. The solids were filtered using a 500 mL cellulose acetate filter funnel with a 0.45 micron pore size. The solids were washed with deionized water and the total mass of the collected colorless filtrate was 224.7 g. The solid was washed with deionized water. The solid was dried overnight at room temperature under nitrogen protection. The solid was confirmed to be 25.6 g of sodium hydrogen oxalate monohydrate by X-ray diffraction analysis (using a PANalytical X'PERT Model 3040 automated powder diffractometer, Natick, MA). Figure 6 illustrates the X-ray diffraction pattern of the isolated solid.
Purification Methods
Crystallise oxalic acid from distilled water. Dry it in a vacuum over H2SO4. The anhydrous acid can be obtained by drying at 100o overnight. [Beilstein 2 IV 1819.]
Structure and conformation
The dihydrate H2C2O 4·2H2O has space group C52h–P21/n, with lattice parameters a = 611.9 pm, b = 360.7 pm, c = 1205.7 pm, β = 106°19′, Z = 2. The main inter-atomic distances are: C-C 153 pm, C-O1 129 pm, C-O2 119 pm. In theory, oxalic acid dihydrate is one of the very few crystalline substances that exhibit negative area compressibility. Namely, when subjected to isotropic tension stress (negative pressure), the a and c lattice parameters increase as the stress decreases from -1.17? to -0.12 GPa and from -1.17 to -0.51 GPa, respectively.
References
[1] Han, Lipeng , S. Xie , and J. Sun . "Preparation and thermal characterization of oxalic acid dihydrate/bentonite composite as shape-stabilized phase change materials for thermal energy storage." IUMRS International Conference in Asia 2017.
Oxalic acid dihydrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Chuandong Chemical (Group) Co. Ltd. | +86-13637972665 | wxc@cd1958.com | China | 81 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3889 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +8613288715578 | sales@hbmojin.com | China | 12628 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Hebei Andu Technology Com.,Ltd | +86-86-17798073498 +8617798073498 | aduchemical@163.com | China | 296 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Jiangsu Kolod Food Ingredients Co.,Ltd. | +8618805133257 | sales3257@jskolod.com | China | 132 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
Related articles
- What is the relationship between oxalic acid and oxalic acid dihydrate?
- Oxalic acid has two forms. One is only oxalic acid, and the other has crystallization watern. The one with no crystallization ....
- Jan 24，2024
View Lastest Price from Oxalic acid dihydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-12 | Oxalic acid dihydrate
6153-56-6
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2025-08-08 | Oxalic acid dihydrate
6153-56-6
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-26 | Oxalic acid dihydrate
6153-56-6
|
US $316.00 / g | 99.39% | 10g | TargetMol Chemicals Inc. |
-
- Oxalic acid dihydrate
6153-56-6
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Oxalic acid dihydrate
6153-56-6
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- Oxalic acid dihydrate
6153-56-6
- US $316.00 / g
- 99.39%
- TargetMol Chemicals Inc.
