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2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Structure
2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide structure
CAS No.
1462267-08-8
Chemical Name:
2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide
Synonyms
ML266;133974;CS-2740;CID-4694321;CID-46943215;ML266, 10 mM in DMSO;2-[(2-{[(4-bromophenyl)carbamoyl]methoxy}phenyl)formamido]-N-methyl-N-phenylacetamide;2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide;Benzamide, 2-[2-[(4-bromophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]-
CBNumber:
CB13049643
Molecular Formula:
C24H22BrN3O4
Molecular Weight:
496.35
MDL Number:
MFCD29477343
MOL File:
1462267-08-8.mol
Last updated:2025-04-17 18:22:24
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2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Properties

Boiling point 724.2±60.0 °C(Predicted)
Density 1.445±0.06 g/cm3(Predicted)
pka 12.31±0.70(Predicted)
form Solid
color White to off-white

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation BRS0009215 2-(2-((4-BROMOPHENYL)AMINO)-2-OXOETHOXY)-N-(2-(METHYL(PHENYL)AMINO)-2-OXOETHYL)BENZAMIDE 95.00% 1462267-08-8 5MG $504.9 2021-12-16 Buy
DC Chemicals DC43043 ML266 >98% 1462267-08-8 100mg $850 2021-12-16 Buy
Product number Packaging Price Buy
BRS0009215 5MG $504.9 Buy
DC43043 100mg $850 Buy

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Chemical Properties,Uses,Production

Uses

ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 μM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease[1].

References

[1] Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7]. PMID:23762943

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide synthesis

106-40-1
1462267-08-8
Synthesis of 2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide from 4-Bromoaniline

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Preparation Products And Raw materials

Raw materials

methyl 2-(2-((4-bromophenyl)amino)-2-oxoethoxy)benzoate N-(4-BROMOPHENYL)-2-CHLOROACETAMIDE 2-AMINO-N-METHYL-N-PHENYL-ACETAMIDE 4-Bromoaniline

Preparation Products

2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30230 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
ChemShuttle, Inc. 0150-83588313-811 18800520310 sales@chemshuttle.com China 2999 62
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4648 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Career Henan Chemica Co 		58
ANHUI WITOP BIOTECH CO., LTD 		58
InvivoChem 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
ChemShuttle, Inc. 62
Shanghai Lollane Biological Technology Co.,Ltd. 55

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2-(2-((4-bromophenyl)amino)-2-oxoethoxy)-N-(2-(methyl(phenyl)amino)-2-oxoethyl)benzamide CID-46943215 ML266 133974 CS-2740 Benzamide, 2-[2-[(4-bromophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]- CID-4694321 2-[(2-{[(4-bromophenyl)carbamoyl]methoxy}phenyl)formamido]-N-methyl-N-phenylacetamide ML266, 10 mM in DMSO 1462267-08-8