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Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone

CAS No.
Chemical Name:
Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone
Synonyms
Z-WEHD-FMK;Z-WE(OME)-HD(OME)-FMK;CASPASE-5 INHIBITOR I;Z-TRP-GLU(OME)-HIS-ASP(OME)-FMK;Z-WE(OME)HD(OME)-FLUOROMETHYLKETONE;CASPASE-1 INHIBITOR (FLUOROMETHYLKETONE);Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone;BENZYLOXYCARBONYL-TRP-GLU(OME)-HIS-ASP(OME)-FLUOROMETHYLKETONE
CBNumber:
CB1329472
Molecular Formula:
C37H42FN7O10
Molecular Weight:
763.77
MDL Number:
MFCD01862606
MOL File:
Mol file
Last updated:2026-09-12 18:49:11

Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone Properties

storage temp. −20°C
solubility DMSO: 5mg/mL
form solid
color white
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  WGK 1
Storage Class 11 - Combustible Solids

Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation PEP0011708 Z-TRP-GLU(OME)-HIS-ASP(OME)-FLUOROMETHYLKETONE 95.00% 5MG $499.11 2021-12-16 Buy
Product number Packaging Price Buy
PEP0011708 5MG $499.11 Buy

Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone Chemical Properties,Uses,Production

Uses

A potent, cell-permeable and irreversible inhibitor of caspase-5 (ICErel-III, TY), as well as caspase-1 and caspase-4.
A potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.

Biological Activity

Caspase-5 inhibitor. Inhibits ECyd-induced rRNA fragmentation in mouse mammary tumor and human fibrosarcoma cells.

Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alabiotech Inc. 001-619-354-5251 sales@alabiotech-e.com United States 972 60
Alpha Biopharmaceuticals Co., Ltd 0411-39042497 sales@alphabiopharm.com China 1951 58
BENZYLOXYCARBONYL-TRP-GLU(OME)-HIS-ASP(OME)-FLUOROMETHYLKETONE CASPASE-5 INHIBITOR I CASPASE-1 INHIBITOR (FLUOROMETHYLKETONE) Z-TRP-GLU(OME)-HIS-ASP(OME)-FMK Z-WEHD-FMK Z-WE(OME)HD(OME)-FLUOROMETHYLKETONE Z-WE(OME)-HD(OME)-FMK Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone C37H42FN7O11 Caspase 5 Caspase Inhibitors Caspases Inhibitors Caspase 1Caspase Inhibitors and Substrates Caspase 1Caspases Caspase 5Caspase Inhibitors and Substrates