Pam2CSK4
- CAS No.
- 868247-72-7
- Chemical Name:
- Pam2CSK4
- Synonyms
- Pam2CSK4;L-Lysine, S-[(2R)-2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-
- CBNumber:
- CB13310330
- Molecular Formula:
- C65H126N10O12S
- Molecular Weight:
- 1271.82
- MDL Number:
- MFCD22683858
- MOL File:
- 868247-72-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Pam2CSK4 (Biotin) Asreported | 256159 | 100ug | $460 |
| Pam2CSK4 ≥95%(HPLC) | 256158 | 1mg | $489 |
| Pam2CSK4 | TJB24772 | 5mg | $1339.95 |
| Pam2CSK4 | TJB24772 | 10mg | $2143.9 |
| Pam2CSK4 | TJB24772 | 25mg | $4020 |
| Boiling point | 1302.9±65.0 °C(Predicted) |
|---|---|
| Density | 1.091±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble to 1 mg/ml in 0.25% acetic acid |
| form | Powder |
| pka | 3.27±0.10(Predicted) |
| color | White |
| Sequence | {(2R)-2,3-Bis(1-oxohexadecyl)oxy]propyl}-Cys-Ser-Lys-Lys-Lys-Lys |
| FDA UNII | L33ZW7BO91 |
Pam2CSK4 price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 256159 | Pam2CSK4 (Biotin) Asreported | 868247-72-7 | 100ug | $460 | 2026-06-03 | Buy |
| Usbiological | 256158 | Pam2CSK4 ≥95%(HPLC) | 868247-72-7 | 1mg | $489 | 2026-06-03 | Buy |
| Biosynth | TJB24772 | Pam2CSK4 | 868247-72-7 | 5mg | $1339.95 | 2026-06-05 | Buy |
| Biosynth | TJB24772 | Pam2CSK4 | 868247-72-7 | 10mg | $2143.9 | 2026-06-05 | Buy |
| Biosynth | TJB24772 | Pam2CSK4 | 868247-72-7 | 25mg | $4020 | 2026-06-05 | Buy |
Pam2CSK4 Chemical Properties,Uses,Production
Uses
Pam2CSK4, a lipopeptide, is a TLR6-independent TLR2 ligand and agonist. Pam2CSK4 promotes platelet aggregation, and increases platelet adhesion to collagen-coated surfaces in a TLR2/NF-κB/BTK-dependent manner. Pam2CSK4 also activates iNOS expression and NO production in mouse macrophages[1][2][3].
storage
-20°C
References
[1] Parra-Izquierdo I, et al. The Toll-Like Receptor 2 Ligand Pam2CSK4 Activates Platelet Nuclear Factor-κB and Bruton's Tyrosine Kinase Signaling to Promote Platelet-Endothelial Cell Interactions. Front Immunol. 2021 Aug 30;12:729951. DOI:10.3389/fimmu.2021.729951
[2] Kulsantiwong P, et al. Pam2CSK4 and Pam3CSK4 induce iNOS expression via TBK1 and MyD88 molecules in mouse macrophage cell line RAW264.7. Inflamm Res. 2017 Oct;66(10):843-853. DOI:10.1007/s00011-017-1063-1
[3] Kaur A, et al. An efficient and scalable synthesis of potent TLR2 agonistic PAM2CSK4. RSC Adv. 2018 Mar 5;8(18):9587-9596. DOI:10.1039/c8ra01387j
Pam2CSK4 Preparation Products And Raw materials
Raw materials
Preparation Products
Pam2CSK4 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | sales@sarms4muscle.com | China | 10378 | 58 |
| Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd | 18020125070 | sales002@jszkhy.com | China | 2106 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29988 | 65 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Hangzhou Go Top Peptide Biotech | 0571-88211921 13336126704 | sales7@gotopbio.com | China | 2987 | 58 |
| Shaoxing Junyu Biotechnology Co., LTD | 0571-0571-88211921 19105816207 | sales4@gotopbio.com | China | 5135 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
