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RUC-4

RUC-4 Structure
RUC-4 structure
CAS No.
1448313-27-6
Chemical Name:
RUC-4
Synonyms
Zalunfiban;RUC-4;CPD1217;2-Amino-N-[5-[5-oxo-7-(1-piperazinyl)-5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-2-yl]-3-pyridinyl]acetamide;2-Amino-N-(4-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-2-yl)acetamide;Acetamide, 2-amino-N-[5-[5-oxo-7-(1-piperazinyl)-5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-2-yl]-3-pyridinyl]-
CBNumber:
CB13334086
Molecular Formula:
C16H18N8O2S
Molecular Weight:
386.43
MDL Number:
MFCD31624244
MOL File:
1448313-27-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-28 08:09:05
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RUC-4 Properties

Density 1.702±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 12.449±0.70(predicted)
FDA UNII 5XQC91CO1F

RUC-4 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth YHC31327 2-Amino-N-(4-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-2-yl)acetamide 1448313-27-6 5mg $849 2026-06-05 Buy
Biosynth YHC31327 2-Amino-N-(4-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-2-yl)acetamide 1448313-27-6 10mg $1358.4 2026-06-05 Buy
Biosynth YHC31327 2-Amino-N-(4-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-2-yl)acetamide 1448313-27-6 25mg $2214.75 2026-06-05 Buy
Biosynth YHC31327 2-Amino-N-(4-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-2-yl)acetamide 1448313-27-6 50mg $3543.5 2026-06-05 Buy
DC Chemicals DC21593 RUC-4 >98% 1448313-27-6 5mg $350 2026-05-24 Buy
Product number Packaging Price Buy
YHC31327 5mg $849 Buy
YHC31327 10mg $1358.4 Buy
YHC31327 25mg $2214.75 Buy
YHC31327 50mg $3543.5 Buy
DC21593 5mg $350 Buy

RUC-4 Chemical Properties, Uses, Production

Uses

Zalunfiban (RUC-4) is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban can be used for the research of myocardial infarction (MI)[1].

in vivo

Zalunfiban (1~3.86 mg/kg; s.c.; 24 hours) makes platelet aggregation performed[1].
Zalunfiban (1~3.86 mg/kg; i.m.; 4.5 hours) leads to the onset of high-grade inhibition of platelet aggregation within 15-30 minutes that lasted from ~2 to >4.5 hours in a dose dependent manner[1].

Animal Model:Cynomolgus Monkey
Dosage:1~3.86 mg/kg (Pharmacokinetic Analysis)
Administration:S.c.; 24 hours
Result:Platelet aggregation was performed.

References

[1] Vootukuri S, et al. Preclinical Studies of RUC-4, a Novel Platelet αIIbβ3 Antagonist, in Non-Human Primates and With Human Platelets. J Clin Transl Sci. 2019;3(2-3):65-74. DOI:10.1017/cts.2019.382

RUC-4 Preparation Products And Raw materials

Raw materials

Preparation Products

RUC-4 Suppliers

Global Suppliers ( 12)
Supplier Tel Email Country ProdList Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3057 58
Suzhou Rovathin Foreign Trade Co.,Ltd 0512-65816829 18662214788 info@rovathin.com.cn China 9959 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6288 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 15000803246 18149758185 sales-cpd@caerulumpharma.com China 474 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai Beckham Medical Technology Co., Ltd 55
Jinan Yaoyan Pharmaceutical Co., Ltd. 58
Suzhou Rovathin Foreign Trade Co.,Ltd 58
TargetMol Chemicals Inc. 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 58
TargetMol Chemicals Inc. 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
TargetMol Chemicals Inc. 58

View Latest Price from RUC-4 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Zalunfiban pictures 2026-07-27 Zalunfiban
1448313-27-6
 $1670.00-2800.00 10g TargetMol Chemicals Inc.
  • Zalunfiban pictures
  • Zalunfiban
    1448313-27-6
  • $1670.00-2800.00
  • TargetMol Chemicals Inc.

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Cyclo (Arg-Gly-Asp-D-Phe-Lys)

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CPD1217 RUC-4 Acetamide, 2-amino-N-[5-[5-oxo-7-(1-piperazinyl)-5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-2-yl]-3-pyridinyl]- 2-Amino-N-[5-[5-oxo-7-(1-piperazinyl)-5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-2-yl]-3-pyridinyl]acetamide 2-Amino-N-(4-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-2-yl)acetamide Zalunfiban 1448313-27-6