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AZD-1390

AZD-1390 Structure
AZD-1390 structure
CAS No.
2089288-03-7
Chemical Name:
AZD-1390
Synonyms
CS-2816;AZD-1390;AZD-1390;AZD 1390;azd1390, 10 mM in DMSO;azd1390,ATM/ATR,azd-1390,ATM and RAD3 related,AZD 1390,inhibit,Inhibitor,Ataxia telangiectasia mutated;7-fluoro-1-isopropyl-3-methyl-8-(6-(3-(piperidin-1-yl)propoxy)pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one;7-fluoro-1-isopropyl-3-methyl-8-(6-(3-(piperidin-1-yl)propoxy)pyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one;7-Fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-2H-imidazo[4,5-c]quinolin-2-one;2H-Imidazo[4,5-c]quinolin-2-one, 7-fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-
CBNumber:
CB13364535
Molecular Formula:
C27H32FN5O2
Molecular Weight:
477.57
MDL Number:
MFCD31619275
MOL File:
2089288-03-7.mol
Last updated:2025-04-17 18:22:24
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AZD-1390 Properties

Boiling point 617.4±55.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO:10.0(Max Conc. mg/mL);20.93(Max Conc. mM)
Ethanol:80.0(Max Conc. mg/mL);168.51(Max Conc. mM)
form A solid
pka 9.22±0.10(Predicted)
color White to off-white
FDA UNII CI43QFE22O

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

AZD-1390 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-8217 AZD1390 99.97% 2089288-03-7 1mg $100 2021-12-16 Buy
ChemScene CS-8217 AZD1390 99.97% 2089288-03-7 5mg $200 2021-12-16 Buy
ChemScene CS-8217 AZD1390 99.97% 2089288-03-7 10mg $290 2021-12-16 Buy
ChemScene CS-8217 AZD1390 99.97% 2089288-03-7 25mg $590 2021-12-16 Buy
Biorbyt Ltd orb573348 AZD1390 >98% 2089288-03-7 100mg $986 2021-12-16 Buy
Product number Packaging Price Buy
CS-8217 1mg $100 Buy
CS-8217 5mg $200 Buy
CS-8217 10mg $290 Buy
CS-8217 25mg $590 Buy
orb573348 100mg $986 Buy

AZD-1390 Chemical Properties,Uses,Production

Uses

AZD 1390 is a potent, highly selective, orally bioavailable, brain-penetrant ATM inhibitor.

in vivo

Median survival of mice treated with AZD1390 and radiation are significantly longer than untreated control mice (p=0.001). No overt signs of treatment toxicity are observed with small animal radiation research platform (SARRP) contrary to wholehead irradiated mice that seem to develop mucositis and difficulties drinking and eating at doses >10 Gy in combination with AZD1390[2].

IC 50

ATM

AZD-1390 Preparation Products And Raw materials

Raw materials

Preparation Products

AZD-1390 Suppliers

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32268 58
Shenzhen Shengda Pharma Limited 		755-85269922 +8613424394241 sales@shengdapharm.com CHINA 310 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38663 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8467 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Hangzhou ChangCun Biotechnology Co., Ltd. 0571-; 13567100326 158848739@qq.com China 108 50
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 12952 65
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9484 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3466 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shenzhen Shengda Pharma Limited 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
Hangzhou ChangCun Biotechnology Co., Ltd. 50
BOC Sciences 65
Shanghai Topbiochem Technology Co., Ltd 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 58

View Lastest Price from AZD-1390 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
azd1390 pictures 2025-05-02 azd1390
2089288-03-7
 US $80.00-163.00 / mg 97.47% 10g TargetMol Chemicals Inc.
  • azd1390 pictures
  • azd1390
    2089288-03-7
  • US $80.00-163.00 / mg
  • 97.47%
  • TargetMol Chemicals Inc.

AZD-1390 Spectrum

AZD-1390(2089288-03-7)MS
CS-2816 7-Fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-2H-imidazo[4,5-c]quinolin-2-one AZD-1390;AZD 1390 AZD-1390 2H-Imidazo[4,5-c]quinolin-2-one, 7-fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]- 7-fluoro-1-isopropyl-3-methyl-8-(6-(3-(piperidin-1-yl)propoxy)pyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one azd1390,ATM/ATR,azd-1390,ATM and RAD3 related,AZD 1390,inhibit,Inhibitor,Ataxia telangiectasia mutated 7-fluoro-1-isopropyl-3-methyl-8-(6-(3-(piperidin-1-yl)propoxy)pyridin-3-yl)-1H-imidazo[4,5-c]quinolin-2(3H)-one azd1390, 10 mM in DMSO 2089288-03-7 C27H32FN5O2