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Echitovenidine

CAS No.
7222-35-7
Chemical Name:
Echitovenidine
Synonyms
Echitovenidine;Aspidospermidine-3-carboxylic acid, 2,3-didehydro-20-[(3-methyl-1-oxo-2-butenyl)oxy]-, methyl ester, (5α,12R,19α,20R)-
CBNumber:
CB13372569
Molecular Formula:
C26H32N2O4
Molecular Weight:
436.54
MDL Number:
MOL File:
7222-35-7.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:40

Echitovenidine Chemical Properties,Uses,Production

Description

Echitovenidine is an alkaloid isolated from the fruits of Alstonia venenata. In vitro and in vivo studies revealed that echitovenidine has an inhibitory effect on monoamine oxidase.

Uses

Echitovenidine is an alkaloid that can be isolated from Alstonia yunnanensis. Echitovenidine is an inhibitor of monoamine oxidase (MAO)[1].

in vivo

Echitovenidine (50 mg/kg, IP) significantly potentiates the analgesic effect of a subanalgesic dose of morphine[1].
The LD50 of Echitovenidine in mice was 126 ± 23 mg/kg (IP)[1].
Echitovenidine produces a transient depressor response in anaesthetised dog, with no significant effect on respiration, in dose of 10 mg/kg[1].

References

[1] Bhattacharya SK,et al. Psychopharmacological studies on echitovenidine. Pharmacol Res Commun. 1976 Apr;8(2):159-66. DOI:10.1016/0031-6989(76)90005-9

Echitovenidine Preparation Products And Raw materials

Raw materials

Preparation Products

Echitovenidine Suppliers

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Echitovenidine Aspidospermidine-3-carboxylic acid, 2,3-didehydro-20-[(3-methyl-1-oxo-2-butenyl)oxy]-, methyl ester, (5α,12R,19α,20R)- 7222-35-7