Sineptina
- CAS No.
- 1392-21-8
- Chemical Name:
- Sineptina
- Synonyms
- KITASAMYCIN;KITASAMYCIN BASE;LEUCOMYCIN HYDRATE;Leucomycins;c637;Ayermycin;Sineptina;Syneptine;ayermicina;guitamycin
- CBNumber:
- CB1338872
- Molecular Formula:
- C35H59NO13
- Molecular Weight:
- 701.84186
- MDL Number:
- MFCD00210322
- MOL File:
- 1392-21-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 128-145 °C |
|---|---|
| storage temp. | Sealed in dry,2-8°C |
| solubility | ethanol: 50 mg/mL, clear to slightly hazy, light-yellow |
| form | Solid |
| color | White to Off-White |
| Merck | 14,5453 |
| InChIKey | XYJOGTQLTFNMQG-XMWOZFRUSA-N |
| CAS DataBase Reference | 1392-21-8 |
| EWG's Food Scores | 1 |
| FDA UNII | G986N7X02W |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P501 |
| Safety Statements | 24/25 |
| WGK Germany | 1 |
| RTECS | WG9400000 |
| F | 10 |
| HS Code | 29419090 |
| Toxicity | mouse,LD50,intraperitoneal,1758mg/kg (1758mg/kg),Drugs in Japan Vol. -, Pg. 354, 1995. |
Sineptina price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 31721 | Leucomycin hydrate | 1392-21-8 | 250mg | $114 | 2022-05-15 | Buy |
| TRC | TRC-L330320-5G | Leucomycins (>85%) | 1392-21-8 | 5g | $66 | 2026-06-03 | Buy |
| TRC | TRC-L330320-250MG | Leucomycins (>85%) | 1392-21-8 | 250mg | $65 | 2026-06-03 | Buy |
| TRC | TRC-L330320-10G | Leucomycins (>85%) | 1392-21-8 | 10g | $119 | 2026-06-03 | Buy |
| Biosynth | AK65051 | Kitasamycin | 1392-21-8 | 25g | $288.25 | 2026-06-04 | Buy |
Sineptina Chemical Properties, Uses, Production
Description
Kitasamycin, formerly called leucomycin, was found in the culture broth of Streptoverticillium kitasatoensis by Hata et al. of the Kitasato Institute, Japan, in 1953. This was the first macrolide antibiotic with a 16-membered lactone constituent. Kitasamycin is a complex of eight leucomycin A components and is used in its base and ester forms to treat gram-positive bacterial and gram-negative coccal infections, as well as infections of Mycoplasma, Spirochaeta, and Treponema by injection or by oral topical administration.
Chemical Properties
White or yellow crystalline powder, odorless, bitter taste. Easily soluble in methanol, ethanol, acetone, ether and chloroform, insoluble in water, oral LD50 in mice (3.8±0.3)g/kg, oral LD50 in rats >8g/kg.
Uses
Sineptina is a family of closely related macrocyclic lactone antibiotics produced by Streptomyces kitasatoensis, discovered in 1953. The complex contained over 14 components with analogues A1, A4, A5, and A13 being the most abundant analogues.Sineptina is used as an animal health product for control of Gram positive bacteria, Gram negative cocci, leptospira and mycoplasma.
Uses
Leucomycins (>85%) (cas# 1392-21-8) is a compound useful in organic synthesis.
Definition
ChEBI: Leucomycin V is a macrolide antibiotic produced by Streptomyces kitasatoensis, showing activity against a wide spectrum of pathogens. It has a role as a bacterial metabolite. It is a leucomycin and a macrolide antibiotic.
Pharmaceutical Applications
A naturally occurring product of Streptomyces kitasatoensis, available in Japan for parenteral and oral use, and as acetylkitasamycin for topical application. Elsewhere it is chiefly used in veterinary medicine.
Sineptina Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6742 | 52 |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Wuhan Fortuna Chemical Co., Ltd | 027-59207852 13308628970 | buy@fortunachem.com | China | 2690 | 58 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
| TCI Europe | 320-37350700 | sales@tcieurope.eu | Europe | 23654 | 75 |
View Latest Price from Sineptina manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-16 | Sineptina
1392-21-8
|
1KG | ≥1320u/mg | 1000KGS | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-01 | Kitasamycin
1392-21-8
|
1kg | 99% | 1000kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | ||
 |
2026-06-02 | Leucomycin
1392-21-8
|
$30.00-64.00 | N/A | 10g | TargetMol Chemicals Inc. |
-
- Sineptina
1392-21-8
- $0.00
- ≥1320u/mg
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Kitasamycin
1392-21-8
- $0.00
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- Leucomycin
1392-21-8
- $30.00-64.00
- N/A
- TargetMol Chemicals Inc.
