5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID
- CAS No.
- 69254-37-1
- Chemical Name:
- 5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID
- Synonyms
- ARACHIDONIC ACID-D8;ARACHIDONIC-5,6,8,9,11,12,14,15-D8 ACID;5,6,8,9,11,12,14,15-D8-Arachidonic Acid;ARACHIDONIC ACID (5,6,8,9,11,12,14,15-D8);5,6,8,9,11,12,14,15-2H8]-Arachidonic Acid;Arachidonic Acid-d8 Lipid Maps MS Standard;ARACHIDONIC ACID (5,6,8,9,11,12,14,15-D8, 98%);Arachidonic acid (5,6,8,9,11,12,14,15-D?, 98%);Arachidonic-5,6,8,9,11,12,14,15-d8 acid;cis-5,8,11,14-Eicosatetraenoic-5,6,8,9,11,12,14,15-d8
- CBNumber:
- CB1340213
- Molecular Formula:
- C20H32O2
- Molecular Weight:
- 304.47
- MDL Number:
- MFCD00065888
- MOL File:
- 69254-37-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Arachidonic acid-5,6,8,9,11,12,14,15-d8 ≥98 atom % D, 98% (CP) | 735000 | 5mg | $502 |
| Arachidonic Acid-d8 ≥99% deuterated forms (d1-d8) | 390010 | 1mg | $122 |
| Arachidonic Acid-d8 ≥99% deuterated forms (d1-d8) | 390010 | 5mg | $395 |
| Arachidonic Acid-d8 ≥99% deuterated forms (d1-d8) | 390010 | 10mg | $669 |
| Arachidonic Acid-d8 | 441727 | 1mg | $566 |
| More product size | |||
| Melting point | -49 °C(lit.) |
|---|---|
| Boiling point | 169-171 ;°C/0.15 ;mmHg(lit. ) |
| Density | 0.945 g/mL at 25 °C |
| Flash point | -16 °C |
| storage temp. | -20°C |
| solubility | 0.1 M Na2CO3: 1.7 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: Miscible |
| form | methyl acetate solution |
| color | Colorless to light yellow |
| Stability | Light Sensitive, Temperature Sensitive |
| InChIKey | YZXBAPSDXZZRGB-FBFLGLDDSA-N |
| SMILES | [2H]\C(CCCCC)=C(/[2H])C\C([2H])=C(\[2H])C\C([2H])=C(\[2H])C\C([2H])=C(\[2H])CCCC(O)=O |
| UNSPSC Code | 12352106 |
| NACRES | NA.24 |
| CAS Number Unlabeled | 506-32-1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319-H336 | |||||||||
| Precautionary statements | P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501 | |||||||||
| Hazard Codes | F,Xi | |||||||||
| Risk Statements | 11-36-66-67-19 | |||||||||
| Safety Statements | 16-26-29-33 | |||||||||
| RIDADR | UN 1231 3/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| NFPA 704 |
|
5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 735000 | Arachidonic acid-5,6,8,9,11,12,14,15-d8 ≥98 atom % D, 98% (CP) | 69254-37-1 | 5mg | $502 | 2026-03-19 | Buy |
| Cayman Chemical | 390010 | Arachidonic Acid-d8 ≥99% deuterated forms (d1-d8) | 69254-37-1 | 1mg | $122 | 2024-03-01 | Buy |
| Cayman Chemical | 390010 | Arachidonic Acid-d8 ≥99% deuterated forms (d1-d8) | 69254-37-1 | 5mg | $395 | 2024-03-01 | Buy |
| Cayman Chemical | 390010 | Arachidonic Acid-d8 ≥99% deuterated forms (d1-d8) | 69254-37-1 | 10mg | $669 | 2024-03-01 | Buy |
| Usbiological | 441727 | Arachidonic Acid-d8 | 69254-37-1 | 1mg | $566 | 2021-12-16 | Buy |
5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID Chemical Properties,Uses,Production
Description
Arachidonic acid-
Uses
Arachidonic Acid-d8 is the deuterated form of Arachidonic Acid (A765000), which is an essential fatty acid and a precursor in biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in the liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and it is also a constituent of animal phosphatides.
References
[1] ROBERT D. BURGOYNE Alan M. The control of free arachidonic acid levels[J]. Trends in Biochemical Sciences, 1990, 15 10: Pages 365-366. DOI: 10.1016/0968-0004(90)90227-3
[2] ANDREW B. NIXON Robert L W Dianne G Greene. Comparison of acceptor and donor substrates in the CoA-independent transacylate reaction in human neutrophils[J]. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996, 1300 3: Pages 187-196. DOI: 10.1016/0005-2760(96)00011-2
[3] BINGPENG YAN. Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication.[J]. Viruses, 2019. DOI: 10.3390/v11010073
[4] MYUNGSUN SHIN . Diacylglycerol Lipase-β Is Required for TNF-α Response but Not CD8+ T Cell Priming Capacity of Dendritic Cells[J]. Cell Chemical Biology, 2019, 26 7: Pages 1036-1041.e3. DOI: 10.1016/j.chembiol.2019.04.002
[5] SEVIM ERCAN. Induction of omega 6 inflammatory pathway by sodium metabisulfite in rat liver and its attenuation by ghrelin.[J]. Lipids in Health and Disease, 2015, 14: 7. DOI: 10.1186/s12944-015-0008-3
[6] VOJISLAV JOVANOVI. Lipid anti-lipid antibody responses correlate with disease activity in systemic lupus erythematosus.[J]. ACS Applied Bio Materials, 2013: e55639. DOI: 10.1371/journal.pone.0055639
[7] CAROL A ROUZER Lawrence J M. Glycerylprostaglandin synthesis by resident peritoneal macrophages in response to a zymosan stimulus.[J]. The Journal of Biological Chemistry, 2005: 26690-26700. DOI: 10.1074/jbc.m501021200
5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yichang Zhongyitai Trading Co., Ltd. | 0717-6449896 13886658719 | root@zhongyitai.com | China | 1978 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 | shenlinxing@macklin.cn | China | 15781 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4511 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 86249 | 60 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Manhag Testing Technology Co., Ltd | 020-3846 2365 19110442770 | 458677837@qq.com | China | 7775 | 58 |
| Reer Technology (Shanghai) Co., LTD | 021-64400900 15800436310 | bessey@reertech.com | China | 4105 | 58 |
| CHINA ISOTOPE CO., LIMITED | 02151600108 13062666369 | info@isotopechem.com | China | 4724 | 58 |
