ChemicalBook >> CAS DataBase List >>1-Acetyl-2-imidazolidinone

1-Acetyl-2-imidazolidinone

1-Acetyl-2-imidazolidinone structure

CAS No.: 5391-39-9

Chemical Name:: 1-Acetyl-2-imidazolidinone

Synonyms: RARECHEM AQ NN 0041;ACETYL IMIDAZO-2-ONE;Clonidine Impurity A;Acetyl Ethylene Urea;Clonidine EP Impurity A;N-Acetylimidazolidinone;Clonidine IMpurity-A(BP);1-Acetyl-2-Imidazolidone;1-acetyl-2-imidazolidine;1-ACETYL-2-IMIDAZOLIDINONE

CBNumber:: CB1370702

Molecular Formula:: C5H8N2O2

Molecular Weight:: 128.13

MDL Number:: MFCD00988254

MOL File:: 5391-39-9.mol

MSDS File:: SDS

Last updated:2026-01-13 11:12:11

Product description	Number	Pack Size	Price
1-ACETYL-2-IMIDAZOLIDINONE Aldrich^CPR	R593206	1 unit	$197
1-ACETYL-2-IMIDAZOLIDINONE AldrichCPR	R593206	50MG	$179
1-Acetyl-2-imidazolidinone >98.0%(GC)	A1945	5g	$41
1-Acetyl-2-imidazolidinone >98.0%(GC)	A1945	25g	$203
1-Acetyl-2-imidazolidinone	A167955	25g	$305
More product size

Request For Quotation

1-Acetyl-2-imidazolidinone Properties

Melting point	173-175°C
Density	1.237
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly, Heated)
pka	12.11±0.20(Predicted)
form	Solid
color	White to Off-White
InChI	InChI=1S/C5H8N2O2/c1-4(8)7-3-2-6-5(7)9/h2-3H2,1H3,(H,6,9)
InChIKey	JJWACYUTERPMBM-UHFFFAOYSA-N
SMILES	C1(=O)N(C(C)=O)CCN1
CAS DataBase Reference	5391-39-9(CAS DataBase Reference)
FDA UNII	I618FH9ZLM

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313

HS Code

2933.29.9000

NFPA 704

	0
2		0

1-Acetyl-2-imidazolidinone price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	R593206	1-ACETYL-2-IMIDAZOLIDINONE Aldrich^CPR	5391-39-9	1 unit	$197	2026-03-19	Buy
Sigma-Aldrich	R593206	1-ACETYL-2-IMIDAZOLIDINONE AldrichCPR	5391-39-9	50MG	$179	2024-03-01	Buy
TCI Chemical	A1945	1-Acetyl-2-imidazolidinone >98.0%(GC)	5391-39-9	5g	$41	2026-03-19	Buy
TCI Chemical	A1945	1-Acetyl-2-imidazolidinone >98.0%(GC)	5391-39-9	25g	$203	2026-03-19	Buy
TRC	A167955	1-Acetyl-2-imidazolidinone	5391-39-9	25g	$305	2021-12-16	Buy

Product number	Packaging	Price	Buy
R593206	1 unit	$197	Buy
R593206	50MG	$179	Buy
A1945	5g	$41	Buy
A1945	25g	$203	Buy
A167955	25g	$305	Buy

1-Acetyl-2-imidazolidinone Chemical Properties,Uses,Production

Uses

1-Acetyl-2-imidazolidinone (Clonidine EP Impurity A) is a synthetic reagent used in the preparation of triple [14C]-labelled moxonidine which is an antihypertensive compound.

Uses

1-Acetyl-2-imidazolidinone (Clonidine EP Impurity A) is a synthetic reagent used in the preparation of triple [14C]-labelled moxonidine which is an antihypertensive compound.

Synthesis

120-93-4

108-24-7

5391-39-9

General procedure for the synthesis of 1-acetyl-2-imidazolidinone from 2-imidazolidinone and acetic anhydride: 5.18 g (60.2 mmol) of 2-imidazolidinone and 50 mL of acetic anhydride were added to a 100 mL round-bottom flask. The mixture was placed in an oil bath and the reaction was stirred at 150 °C for 1 hour. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to collect the precipitated solid. The solid was washed with a small amount of cold ethanol to give a final 4.94 g (yield: 64.1%) of colorless solid 1-acetyl-2-imidazolidinone.

References

[1] Chemistry - A European Journal, 2002, vol. 8, # 11, p. 2464 - 2475
[2] Patent: JP2016/145198, 2016, A. Location in patent: Paragraph 0087-0089
[3] Arkivoc, 2014, vol. 2014, # 2, p. 44 - 56
[4] Journal of the American Chemical Society, 1958, vol. 80, p. 6409,6412

1-Acetyl-2-imidazolidinone synthesis

Synthesis of 1-Acetyl-2-imidazolidinone from 2-Imidazolidone and Acetic anhydride

1-Acetyl-2-imidazolidinone Preparation Products And Raw materials

Raw materials

2H-Imidazol-2-one 1-ACETYL-1H-BENZOTRIAZOLE N-Acetylethylenediamine Carbon dioxide Acetyl chloride

2-Imidazolidone Acetic anhydride

1of2

Preparation Products

Tizanidine 3-Acetyl-1-chlorocarbonyl-2-imidazolidone

1-Acetyl-2-imidazolidinone Suppliers

Global( 365)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3692	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1803	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21592	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Zhejiang ZETian Fine Chemicals Co. LTD	+8618957127338	stella@zetchem.com	China	2994	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Zhejiang ZETian Fine Chemicals Co. LTD	58
Standardpharm Co. Ltd.	58

View Lastest Price from 1-Acetyl-2-imidazolidinone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-04-20	1-Acetyl-2-imidazolidinone 5391-39-9	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-03-20	1-Acetyl-2-imidazolidinone 5391-39-9	US $10.00 / KG	1KG	99%	10 mt	Hebei Chuanghai Biotechnology Co., Ltd
2025-12-01	1-Acetyl-2-imidazolidinone 5391-39-9	US $0.00 / kg	1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd

1-Acetyl-2-imidazolidinone
5391-39-9
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

1-Acetyl-2-imidazolidinone
5391-39-9
US $10.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

1-Acetyl-2-imidazolidinone
5391-39-9
US $0.00 / kg
99%
Shaanxi Dideu New Materials Co. Ltd

1-Acetyl-2-imidazolidinone Spectrum

1-Acetyl-2-imidazolidinone(5391-39-9)¹HNMR

5391-39-9(1-Acetyl-2-imidazolidinone )Related Search:

Imidazolidine Acetylacetone Imidazolidinyl urea Acetyl coenzyme A sodium salt N-ACETYL-L-TYROSINE ETHYL ESTER

Acetyl chloride Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) 1,3-Dimethyl-2-imidazolidinone 2-Imidazolidone N-Carbethoxy-4-piperidone

N-(tert-Butoxycarbonyl)-4-piperidone N-ACETYL-(2S)-BORNANE 10,2-SULTAM 1-Acetyl-5-broMo-6-chloro-1H-indol-3-yl acetate 6-CHLOROINDOXYL-1,3-DIACETATE AC-GLU-OME

N-ACETYL-4-S-CYSTEAMINYLPHENOL 1-ACETYL-5-BROMO-7-NITROINDOLINE 1-acetyl-3-bromopiperidin-4-one hydrobromide

1of4

1-ethanoylimidazolidin-2-one N-acetyl-2-iMidazolidazolidinone Clonidine IMpurity-A(BP) Clonidine Impurity A 2-Imidazolidinone,1-acetyl- n-acetyl-2-imidazolidinone RARECHEM AQ NN 0041 ACETYL IMIDAZO-2-ONE 1-ACETYL-IMIDAZOLIDIN-2-ONE 1-ACETYL-1,3,4,5-TETRAHYDROIMIDAZOLE-2-ONE 1-ACETYL-2-IMIDAZOLIDINONE 1-Acetyl-2-Imidazolidone 1-acetylimidazolidine-2-thione Acetyl Ethylene Urea 1-acetyl-2-imidazolidine 1-acetyl-2-imidazol-1-iumone Clonidine Impurity 1（Clonidine EP Impurity A) Clonidine EP Impurity A 1-Acetyl-2-imidazolidinone > N-Acetylimidazolidinone Clonidine Hydrochloride EP Impurity A Clonidine EP Impurity A 1-Acetylimidazolidin-2-one Clonidine Hydrochloride Impurity A 5391-39-9 5391-53-9 C5H8N2O2 Imidazol&Benzimidazole (intermediate of moxonidine hcl)