Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>METHYL 4-BROMO-3-HYDROXYBENZOATE

METHYL 4-BROMO-3-HYDROXYBENZOATE

METHYL 4-BROMO-3-HYDROXYBENZOATE Structure
METHYL 4-BROMO-3-HYDROXYBENZOATE structure
CAS No.
106291-80-9
Chemical Name:
METHYL 4-BROMO-3-HYDROXYBENZOATE
Synonyms
SW 1573[SW-1573,SW1573];METHYL 4-BROMO-3-HYDROXYBENZOATE;Methyl 3-hydroxy-4-bromobenzoate;2-Bromo-5-(methoxycarbonyl)phenol;Methyl4-Bromo-3-hydroxybenzoate>Methyl 4-bromo-3-hydroxybenzoate 98%;Methyl 4-Bromo-3-hydroxybenzoate, >=98%;4-BROMO-3-HYDROXY-BENZOIC ACIDMETHYL ESTER;Benzoic acid, 4-bromo-3-hydroxy-, methyl ester;Benzoic acid, 4-bromo-3-hydroxy-, methyl ester (9CI, ACI)
CBNumber:
CB1377266
Molecular Formula:
C8H7BrO3
Molecular Weight:
231.04
MDL Number:
MFCD08056372
MOL File:
106291-80-9.mol
MSDS File:
SDS
Last updated:2025-09-02 17:37:48
Product description Number Pack Size Price
Methyl 4-Bromo-3-hydroxybenzoate >98.0%(GC) M2246 1g $61
Methyl 4-Bromo-3-hydroxybenzoate >98.0%(GC) M2246 5g $205
4-Bromo-3-hydroxybenzoicAcidMethylEster B684675 100mg $45
Methyl 4-bromo-3-hydroxybenzoate 95+% 075354 1g $50
Methyl 4-bromo-3-hydroxybenzoate 97% OR9408 5g $82
More product size
Request For Quotation

METHYL 4-BROMO-3-HYDROXYBENZOATE Properties

Melting point 121-125
Boiling point 318.0±22.0 °C(Predicted)
Density 1.627±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform, Dichloromethane, Methanol
form Burgandy Color
pka 7.61±0.10(Predicted)
color White to Almost white
InChI InChI=1S/C8H7BrO3/c1-12-8(11)5-2-3-6(9)7(10)4-5/h2-4,10H,1H3
InChIKey VYOFPLOREOHCDP-UHFFFAOYSA-N
SMILES C(OC)(=O)C1=CC=C(Br)C(O)=C1
CAS DataBase Reference 106291-80-9

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xi
Hazard Note  Irritant/Keep Cold
HS Code  2918290090
NFPA 704
0
1 0

METHYL 4-BROMO-3-HYDROXYBENZOATE price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical M2246 Methyl 4-Bromo-3-hydroxybenzoate >98.0%(GC) 106291-80-9 1g $61 2025-07-31 Buy
TCI Chemical M2246 Methyl 4-Bromo-3-hydroxybenzoate >98.0%(GC) 106291-80-9 5g $205 2025-07-31 Buy
TRC B684675 4-Bromo-3-hydroxybenzoicAcidMethylEster 106291-80-9 100mg $45 2021-12-16 Buy
Matrix Scientific 075354 Methyl 4-bromo-3-hydroxybenzoate 95+% 106291-80-9 1g $50 2021-12-16 Buy
Apolloscientific OR9408 Methyl 4-bromo-3-hydroxybenzoate 97% 106291-80-9 5g $82 2021-12-16 Buy
Product number Packaging Price Buy
M2246 1g $61 Buy
M2246 5g $205 Buy
B684675 100mg $45 Buy
075354 1g $50 Buy
OR9408 5g $82 Buy

METHYL 4-BROMO-3-HYDROXYBENZOATE Chemical Properties,Uses,Production

Chemical Properties

Burgandy Color

Uses

Methyl 4-BroMo-3-hydroxybenzoate is a reactant used in the preparation of selective inhibitors.

Synthesis

Methanol

67-56-1

4-BROMO-3-HYDROXYBENZOIC ACID

14348-38-0

METHYL 4-BROMO-3-HYDROXYBENZOATE

106291-80-9

Step A. Synthesis of methyl 4-bromo-3-hydroxybenzoate: To a solution of methanol (100 mL) containing 4-bromo-3-hydroxybenzoic acid (30 mmol) was slowly added concentrated sulfuric acid (2.6 mL). The reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, the mixture was cooled to 0 °C, followed by the slow addition of saturated aqueous sodium carbonate to adjust the pH to 7. The reaction solution was concentrated to one-third of the original volume and diluted with an appropriate amount of water. Extraction was carried out with ethyl acetate and the organic phases were combined. The organic phase was washed with water and saturated saline in turn and dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure to give a white solid product, methyl 4-bromo-3-hydroxybenzoate, 6.15 g (89% yield) with a melting point of 205 °C (literature value: 130-132 °C).

References

[1] Chemical Communications, 2013, vol. 49, # 10, p. 990 - 992
[2] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 16, p. 4863 - 4867
[3] Journal of Medicinal Chemistry, 2007, vol. 50, # 15, p. 3540 - 3560
[4] Patent: US2006/199806, 2006, A1. Location in patent: Page/Page column 23
[5] Patent: WO2005/115996, 2005, A1. Location in patent: Page/Page column 66

METHYL 4-BROMO-3-HYDROXYBENZOATE Preparation Products And Raw materials

Raw materials

4-BROMO-3-HYDROXYBENZOIC ACID Methanol Sulfuric acid Water

Preparation Products

METHYL 4-BROMO-3-METHOXYBENZOATE

METHYL 4-BROMO-3-HYDROXYBENZOATE Suppliers

Global( 200)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8772 58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		+8613288715578 sales@sichuanzyyt.com China 12245 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Wuhan Chemwish Technology Co., Ltd 		027-67849912 sales@chemwish.com CHINA 10821 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29799 58
Jinan Liheng Biotechnology Co., Ltd. 		15865262812 info@lihengpharm.com CHINA 938 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10035 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Sichuan Zhuoyu Yantang Technology Co., Ltd. 		58
Changzhou Ansciep Chemical Co., Ltd. 		58
Accela ChemBio Inc. 		58
Alchem Pharmtech,Inc. 		58
Wuhan Chemwish Technology Co., Ltd 		58
career henan chemical co 		58
Jinan Liheng Biotechnology Co., Ltd. 		58
Fuxin Pharmaceutical 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58

View Lastest Price from METHYL 4-BROMO-3-HYDROXYBENZOATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 4-bromo-3-hydroxybenzoate pictures 2025-10-21 Methyl 4-bromo-3-hydroxybenzoate
106291-80-9
 US $10.00 / KG 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
1-Naphthalenesulfonyl chloride pictures 2025-09-02 1-Naphthalenesulfonyl chloride
106291-80-9
 US $0.00 / KG 1KG 99% 50000KG/month Sichuan Zhuoyu Yantang Technology Co., Ltd.
Methyl 4-bromo-3-hydroxybenzoate pictures 2024-04-25 Methyl 4-bromo-3-hydroxybenzoate
106291-80-9
 US $100.00-30.00 / kg 1kg 99.93% 1000kg per week Ouhuang Engineering Materials (Hubei) Co., Ltd

METHYL 4-BROMO-3-HYDROXYBENZOATE Spectrum

METHYL 4-BROMO-3-HYDROXYBENZOATE(106291-80-9)1HNMRMETHYL 4-BROMO-3-HYDROXYBENZOATE(106291-80-9)FT-IR

106291-80-9(METHYL 4-BROMO-3-HYDROXYBENZOATE)Related Search:

METHYL 4-BROMO-3-METHOXYBENZOATE Methyl 4-BroMo-5-chloro-2-furoate Methyl 4-bromo-3-methylbenzoate METHYL 4-BROMO-3-FLUOROBENZOATE 98 TERT-BUTYL 3-BENZYLOXY-4-BROMOBENZOATE
METHYL 3,5-DIBROMO-4-HYDROXYBENZOATE METHYL 3,5-DIBROMO-2-HYDROXYBENZOATE TERT-BUTYL 4-BROMO-3-METHOXYBENZOATE 98 METHYL 3-(BENZYLOXY)-4-BROMOBENZOATE 98 METHYL 4-BROMO-3-HYDROXYBENZOATE
4-BROMO-3-HYDROXYBENZOIC ACID Methyl 3-hydroxybenzoate TERT-BUTYL 4-BROMO-3,5-DIHYDROXYBENZOATE ETHYL 4-BROMO-3-HYDROXYBENZOATE TERT-BUTYL 4-BROMO-3,5-DIMETHOXYBENZOATE
4-BROMO-3,5-DIMETHOXYBENZOIC ACID METHYL ESTER methyl 4-bromo-3,5-dihydroxy-benzoate METHYL 4-BROMO-2-HYDROXYBENZOATE

1of4

Methyl 4-bromo-3-hydroxybenzoate 98% 4-BROMO-3-HYDROXY-BENZOIC ACIDMETHYL ESTER METHYL 4-BROMO-3-HYDROXYBENZOATE 2-Bromo-5-(methoxycarbonyl)phenol Methyl 3-hydroxy-4-bromobenzoate Methyl 4-Bromo-3-hydroxybenzoate, >=98% SW 1573[SW-1573,SW1573] Methyl4-Bromo-3-hydroxybenzoate> Benzoic acid, 4-bromo-3-hydroxy-, methyl ester Benzoic acid, 4-bromo-3-hydroxy-, methyl ester (9CI, ACI) 106291-80-9 blocks Bromides Carboxes