Hematoxylin
- CAS No.
- 517-28-2
- Chemical Name:
- Hematoxylin
- Synonyms
- Homaeoxylin;hematoxyline;hydroxybrazilin;Hematoxylin powder;HEMATOXYLIN CERTIFIED;HEMATOXYLIN INDICATOR;C.I.75290;nci-c55889;Nsc 270085;Color fine
- CBNumber:
- CB1382426
- Molecular Formula:
- C16H14O6
- Molecular Weight:
- 302.28
- MDL Number:
- MFCD00283323
- MOL File:
- 517-28-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 200 °C (dec.)(lit.) |
|---|---|
| Boiling point | 363.32°C (rough estimate) |
| Density | 1.2514 (rough estimate) |
| bulk density | 500kg/m3 |
| vapor pressure | 0-0Pa at 20-25℃ |
| refractive index | 1.4600 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in 95% ethanol(1 mg/mL). |
| Colour Index | 75290 |
| pka | 6.7(at 25℃) |
| form | Powder/Solid |
| color | Yellow to Brown |
| PH Range | Red (0.0) to yellow (1.0);Pale yellow (5.0) to violet (6.0) |
| optical activity | 77.5°(C=0.01g/mL, MEOH, 20°C, 589nm) |
| Water Solubility | SOLUBLE IN HOT WATER |
| Sensitive | Light Sensitive |
| λmax | 292nm, 445nm, 560nm |
| Merck | 14,4637 |
| BRN | 91399 |
| Stability | Stable, but may discolour on exposure to light. Incompatible with strong oxidizing agents. |
| Major Application | Plasma displays, textiles, hair dyes, identifying fresh and stale rice, diag-nosing cancer progression, detecting nosing cancer progression, cervical disease, central nervous system malfunctions, detecting genes, breast cancer, collagen in a tissue sample, apoptosis, demyelinating diseases, antigens, treatment of age-related macular degeneration, burns, prostate cancer, diabetesand obesity, viral diseases, neoplasms, peripheral neural and vascular ailments, skin disorders, biotechnological applications, reference standard materials for cytology, histology andimmunohistochemistry |
| InChI | 1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1 |
| InChIKey | WZUVPPKBWHMQCE-UHFFFAOYSA-N |
| SMILES | Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O |
| LogP | 0.3 at 30℃ and pH6.9 |
| CAS DataBase Reference | 517-28-2 |
| EWG's Food Scores | 1 |
| FDA UNII | YKM8PY2Z55 |
| EPA Substance Registry System | Hematoxylin (517-28-2) |
| UNSPSC Code | 41116130 |
| NACRES | NA.47 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | MH7875000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 32030019 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| Hazardous Substances Data | 517-28-2(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Hematoxylin price More Price(86)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1.04302 | Hematoxylin cryst. (C.I. 75290) for microscopy | 517-28-2 | 25g | $228 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1.04302 | Hematoxylin cryst. (C.I. 75290) for microscopy | 517-28-2 | 100g | $648 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1.04302 | Hematoxylin cryst. (C.I. 75290) for microscopy | 517-28-2 | 1kg | $7200 | 2026-04-30 | Buy |
| Sigma-Aldrich | 234 | Hematoxylin HARLECO? Nuclear staining | 517-28-2 | 25g | $122 | 2023-01-07 | Buy |
| Sigma-Aldrich | 234 | Hematoxylin HARLECO? Nuclear staining | 517-28-2 | 100g | $424 | 2023-01-07 | Buy |
Hematoxylin Chemical Properties, Uses, Production
Chemical Properties
light brown crystals or powder
Uses
Colorant in inks, biological stains.
Uses
Hematoxylin and eosin together make up Hematoxylin and eosin stain, one of the most commonly used stains in histology. Metal-haematein complexes are used to stain cell nuclei prior to examination under a microscope. Structures that stain with iron- or aluminum-haematein are often called basophilic, even though the mechanism of the staining is different from that of staining with basic dyes.
Definition
ChEBI: (+)-haematoxylin is a haematoxylin. It is an enantiomer of a (-)-haematoxylin.
General Description
White to yellowish crystals that redden on exposure to light.
Air & Water Reactions
Soluble in hot water, slightly water soluble in cold .
Reactivity Profile
Sensitive to light. .
Hazard
May be carcinogenic.
Biological Activity
Hematoxylin is an organic stain which chelates with metal ions and binds to DNA and RNA. It is used for staining nucleus of the cells. Hematoxylin along with eosin stain is used in the diagnosis of invasion stage in tumors.
storage
Store at RT
Purification Methods
Hematoxylin recrystallises from H2O (as trihydrate) in white-yellow crystals which become red on exposure to light and then melt at 100-120o. It has been recrystallised from Me2CO/*C6H6. It has been recrystallised as well from dilute aqueous NaHSO3 until colourless and is soluble in alkali, borax and glycerol. Store it in the dark below 0o. [Morsingh & Robinson Tetrahedron 26 182 1970, Dann & Hofmann Chem Ber 98 1498 1955, Beilstein 17/8 V 469.]
Description
Hematoxylin is a blue nuclear counterstain for use in immunohistochemical assays. It yields crisp staining detail with superior contrast when used in conjunction with SignalStain® DAB Substrate Kit
Hematoxylin Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hu' nan Yunbang Pharmaceutical Co., Ltd. | 88532689 15386497078 | yunbang@yunbangapi.com | China | 6935 | 58 |
| Shanghai Uteam Biotechnology Co., Ltd. | 021-36031160 13311776681 | 3338195766@QQ.com | China | 5091 | 55 |
| Shanghai Biological Technology Development Co., Ltd. | 021-69955236-807 13918189704 | chinaruji@chinaruji.com | China | 5093 | 55 |
| Shanghai Ruili Spectrum Biotechnology Co., Ltd | 021-64705760 18027310741 | 1060496435@qq.com | China | 4562 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| BIOISCO(Lianyungang, Jiangsu) Biotechnology Co., Ltd | 18082049515 | 2757382053@qq.com | China | 2995 | 58 |
| Hunan Zhangjiajie Hengkang Biological Pharmaceutical Co., LTD | 0731-85561023 18973109536 | hengkangapi@hengkangapi.com | China | 402 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
Related Questions
Ask a questionView Latest Price from Hematoxylin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | Hematoxylin
517-28-2
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-18 | Hematoxylin
517-28-2
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-09-11 | Hematoxylin
517-28-2
|
1KG | >99% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. |
-
- Hematoxylin
517-28-2
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Hematoxylin
517-28-2
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Hematoxylin
517-28-2
- $0.00
- >99% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
517-28-2 (Hematoxylin) Related Search:
1of4
