2-AMINO-2-NORBORNANECARBOXYLIC ACID
- CAS No.
- 20448-79-7
- Chemical Name:
- 2-AMINO-2-NORBORNANECARBOXYLIC ACID
- Synonyms
- BCH;B-Bch;LAT1-IN-1;LAT1-IN-1 (BCH);2-AMINO-2-NORBORNANECARBOXYLIC ACID;2-Aminonorbornane-2-carboxylic acid;2-Amino-2-carboxy-bicyclo-2,2,1-heptane;2-AMINOBICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID;3-amino-3-bicyclo[2.2.1]heptanecarboxylic acid;3-aminobicyclo[2.2.1]heptane-3-carboxylic Acid
- CBNumber:
- CB1384309
- Molecular Formula:
- C8H13NO2
- Molecular Weight:
- 155.19
- MDL Number:
- MFCD00167580
- MOL File:
- 20448-79-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | A7902 | 100mg | $132 |
| 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | A7902 | 1g | $748 |
| BCH ≥98% | 15249 | 25mg | $33 |
| BCH ≥98% | 15249 | 50mg | $63 |
| 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | A7902 | 250mg | $249 |
| Melting point | >300 °C(lit.) |
|---|---|
| Boiling point | 295.5±23.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Aqueous Acid (Slightly) |
| pka | 2.58±0.20(Predicted) |
| form | Solid |
| color | White |
| Water Solubility | Soluble to 100 mM in water |
| InChI | 1S/C8H13NO2/c9-8(7(10)11)4-5-1-2-6(8)3-5/h5-6H,1-4,9H2,(H,10,11)/t5-,6+,8/m1/s1 |
| InChIKey | MPUVBVXDFRDIPT-RSHNMJPRSA-N |
| SMILES | NC1(C[C@@H]2CC[C@H]1C2)C(O)=O |
| CAS DataBase Reference | 20448-79-7(CAS DataBase Reference) |
| UNSPSC Code | 12352106 |
| NACRES | NA.26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
2-AMINO-2-NORBORNANECARBOXYLIC ACID price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A7902 | 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | 20448-79-7 | 100mg | $132 | 2026-03-19 | Buy |
| Sigma-Aldrich | A7902 | 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | 20448-79-7 | 1g | $748 | 2026-03-19 | Buy |
| Cayman Chemical | 15249 | BCH ≥98% | 20448-79-7 | 25mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 15249 | BCH ≥98% | 20448-79-7 | 50mg | $63 | 2024-03-01 | Buy |
| Sigma-Aldrich | A7902 | 2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor | 20448-79-7 | 250mg | $249 | 2026-03-19 | Buy |
2-AMINO-2-NORBORNANECARBOXYLIC ACID Chemical Properties,Uses,Production
Uses
2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells
Definition
ChEBI: 2-Amino-2-norbornanecarboxylic acid is a monoterpenoid.
General Description
2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis.
Biochem/physiol Actions
2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells.
storage
Store at RT
2-AMINO-2-NORBORNANECARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-2-NORBORNANECARBOXYLIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32467 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39040 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 6085 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
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