2-Chloroveratraldehyde
- CAS No.
- 5417-17-4
- Chemical Name:
- 2-Chloroveratraldehyde
- Synonyms
- 2-CHLORO-3,4-DIMETHOXYBENZALDEHYDE;TIMTEC-BB SBB003539;Vanillin Impurity 20;2-Chlorveratrumaldehyd;2-CHLOROVERATRALDEHYDE;LABOTEST-BB LT01147597;2‐Chlorovanillin methyl ether;2-Chloro-3,4-dimethoxybenzalde;2-CHLORO-3,4-DIMETHOXYBENZALDE 98%;Benzaldehyde, 2-chloro-3,4-dimethoxy-
- CBNumber:
- CB1386257
- Molecular Formula:
- C9H9ClO3
- Molecular Weight:
- 200.62
- MDL Number:
- MFCD00084942
- MOL File:
- 5417-17-4.mol
- MSDS File:
- SDS
| Melting point | 71-74 °C (lit.) |
|---|---|
| Boiling point | 300.9±37.0 °C(Predicted) |
| Density | 1.245±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly) |
| form | Solid |
| color | White to Pale Yellow |
| Sensitive | Air Sensitive |
| BRN | 2109344 |
| InChI | InChI=1S/C9H9ClO3/c1-12-7-4-3-6(5-11)8(10)9(7)13-2/h3-5H,1-2H3 |
| InChIKey | SAWHDJTZESXNMM-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC=C(OC)C(OC)=C1Cl |
| CAS DataBase Reference | 5417-17-4(CAS DataBase Reference) |
| FDA UNII | CKN4YMM777 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29124900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
2-Chloroveratraldehyde price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 566004 | 2-Chloro-3,4-dimethoxybenzaldehyde 98% | 5417-17-4 | 5g | $209 | 2023-01-07 | Buy |
| TCI Chemical | C1997 | 2-Chloro-3,4-dimethoxybenzaldehyde >98.0%(GC) | 5417-17-4 | 5g | $42 | 2026-04-30 | Buy |
| TCI Chemical | C1997 | 2-Chloro-3,4-dimethoxybenzaldehyde >98.0%(GC) | 5417-17-4 | 25g | $96 | 2026-04-30 | Buy |
| TRC | TRC-C427660-1G | 2-Chloro-3,4-dimethoxybenzaldehyde | 5417-17-4 | 1g | $60 | 2026-06-03 | Buy |
| Apolloscientific | OR28781 | 2-Chloro-3,4-dimethoxybenzaldehyde ≥95% | 5417-17-4 | 1g | $21 | 2026-06-04 | Buy |
2-Chloroveratraldehyde Chemical Properties, Uses, Production
Chemical Properties
beige-yellow to beige crystalline powder
Uses
2-Chloro-3,4-dimethoxybenzaldehyde is a useful reagent in the synthesis of the human TLR4 agonist euodenine A. 2-Chloro-3,4-dimethoxybenzaldehyde is also used as a reagent in the synthesis of novel 2-methoxyacylhydrazones as potent, selective PDE10A inhibitors with activity in animal models of schizophrenia.
Synthesis
37687-57-3
74-88-4
5417-17-4
Step 2 - Formation of 2-chloro-3,4-dimethoxybenzaldehyde: To a 100 mL solution of 8.03 g (43 mmol) of 2-chloro-3-hydroxy-4-methoxybenzaldehyde in acetonitrile was added 7.7 g (55 mmol) of powdered potassium carbonate, followed by the addition of 8.3 mL (0.13 mol) of iodomethane. The reaction mixture was slowly heated to reflux and stirred continuously at this temperature for 24 hours. Upon completion of the reaction, it was cooled to room temperature, the suspension was filtered and the filtrate was evaporated under vacuum to remove the solvent to give 8.5 g (42 mmol, 98% yield) of white solid. The resulting solid was confirmed to be 2-chloro-3,4-dimethoxybenzaldehyde by 1H NMR analysis.
References
[1] Synlett, 2014, vol. 25, # 20, p. 2891 - 2894
[2] Patent: US5866513, 1999, A
2-Chloroveratraldehyde Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Minsuo Technology Co., Ltd. | 571-88199336 18957129209 | 309645123@qq.com | China | 55 | 64 |
| Changzhou Share Chemical Co., Ltd | 0519-82619998 | wu@sharechem.com | China | 29 | 54 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from 2-Chloroveratraldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 2-Chloroveratraldehyde
5417-17-4
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2026-02-02 | 2-Chloroveratraldehyde
5417-17-4
|
10mg | 99%HPLC | 2000tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2020-01-01 | 2-Chloroveratraldehyde
5417-17-4
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 2-Chloroveratraldehyde
5417-17-4
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-Chloroveratraldehyde
5417-17-4
- 99%HPLC
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-Chloroveratraldehyde
5417-17-4
- $1.00
- 99%
- Career Henan Chemical Co
