ChemicalBook >> CAS DataBase List >>(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid

(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid

(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid structure

CAS No.: 859498-34-3

Chemical Name:: (2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid

Synonyms: Cabataxel Impurity 4;Carbataxel impurity 15;Cabazitaxel Impurity 53;Cabazitaxel Initiator 2 impurity A;(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid;(2*,4R,5S)- N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-formic acid;3,5-Oxazolidinedicarboxylic acid, 2-(4-methoxyphenyl)-4-phenyl-, 3-(1,1-dimethylethyl) ester, (4R,5S)-;(4S,5R)-5-((2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-12-(benzoyloxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca;(4S,5R)-5-((2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-12-(benzoyloxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl) 3-tert-butyl 2-(4-methoxyphenyl)-4-phenyloxazolidine-3,5-dicarboxylate

CBNumber:: CB13954804

Molecular Formula:: C22H25NO6

Molecular Weight:: 399.44

MDL Number:: MFCD31382330

MOL File:: 859498-34-3.mol

Last updated:2025-07-04 15:20:04

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(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid Properties

Melting point	129-132 °C
Boiling point	573.8±50.0 °C(Predicted)
Density	1.238±0.06 g/cm3(Predicted)
pka	2.99±0.60(Predicted)
InChI	InChI=1S/C22H25NO6/c1-22(2,3)29-21(26)23-17(14-8-6-5-7-9-14)18(20(24)25)28-19(23)15-10-12-16(27-4)13-11-15/h5-13,17-19H,1-4H3,(H,24,25)/t17-,18+,19/m1/s1
InChIKey	MSVWUXLRSKRKFZ-YTYFACEESA-N
SMILES	O1[C@H](C(O)=O)[C@@H](C2=CC=CC=C2)N(C(OC(C)(C)C)=O)C1C1=CC=C(OC)C=C1

(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	B657930	(4R,5S)-(N-Boc)-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylicAcid	859498-34-3	0.5mg	$165	2021-12-16	Buy

Product number	Packaging	Price	Buy
B657930	0.5mg	$165	Buy

(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid Chemical Properties, Uses, Production

Uses

(4R,5S)-(N-Boc)-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylic Acid is a useful reagent to prepare Docetaxel (D494420) and its isomer.

(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid synthesis

Synthesis of (2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid from Docetaxel Impurity 9

(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Docetaxel Impurity 30 Docetaxel Impurity 9 Benzenepropanoic acid, β-aMino-α-hydroxy-, Methyl ester, (αS,βR)-

Preparation Products

(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid Suppliers

Global Suppliers ( 35)

Supplier	Tel	Email	Country	ProdList	Advantage
Quality Control Solutions Ltd.	0755-66853366 13670046396	orders@qcsrm.com	China	18188	56
BOC Sciences	16314854226	info@bocsci.com	United States	9909	65
Shanghai Shanyuan pharmaceutical technology co., LTD	021-31761238 13167072949	3146446224@qq.com	China	1420	55
Shanghai Yihe Biological Technology Co., Ltd.	021-68882955 17721395025	2423903095@qq.com	China	5000	58
Henan Alfachem Co.,Ltd.	0371-55051623 18137891487	3983243027@qq.com	China	9974	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226	sales@rrkchem.com	China	57336	58
Shanghai Hongle Biotechnology Co., Ltd	021-56145923; 4001631568	sales@honglebiotech.com	China	1036	58
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
Guangzhou Dreampharm Biotechnology Co., Ltd.	020-36607679; 13502246435	3008233746@qq.com	China	9968	12
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14320	58

Supplier	Advantage
Quality Control Solutions Ltd.	56
BOC Sciences	65
Shanghai Shanyuan pharmaceutical technology co., LTD	55
Shanghai Yihe Biological Technology Co., Ltd.	58
Henan Alfachem Co.,Ltd.	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58
Shanghai Hongle Biotechnology Co., Ltd	58
BOC Sciences	58
Guangzhou Dreampharm Biotechnology Co., Ltd.	12
Standardpharm Co. Ltd.	58

(2R,4R,5S)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyloxazolidine-5-carboxylic acid (2*,4R,5S)- N-tert-butoxycarbonyl-2-(4'-methoxy)phenyl-4-phenyl-1,3-oxazolidine-5-formic acid Cabazitaxel Impurity 53 Cabazitaxel Initiator 2 impurity A 3,5-Oxazolidinedicarboxylic acid, 2-(4-methoxyphenyl)-4-phenyl-, 3-(1,1-dimethylethyl) ester, (4R,5S)- Carbataxel impurity 15 Cabataxel Impurity 4 (4S,5R)-5-((2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-12-(benzoyloxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-9-yl) 3-tert-butyl 2-(4-methoxyphenyl)-4-phenyloxazolidine-3,5-dicarboxylate (4S,5R)-5-((2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-12-(benzoyloxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca 859498-34-3