ChemicalBook >> CAS DataBase List >>(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL

CAS No.
31181-84-7
Chemical Name:
(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL
Synonyms
5-(trifluoromethyl)-2-Pyridinemethanol;2-Pyridinemethanol, 5-(trifluoromethyl)-;[5-(Trifluoromethyl)-2-pyridinyl]methanol;(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL;2-HydroxyMethyl-5-(TrifluorMethyl)-Pyridine;2-(Hydroxymethyl)-5-(trifluoromethyl)pyridine;(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL ISO 9001:2015 REACH
CBNumber:
CB1401570
Molecular Formula:
C7H6F3NO
Molecular Weight:
177.12
MDL Number:
MFCD04117762
MOL File:
31181-84-7.mol
Last updated:2025-07-24 18:13:45

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL Properties

Boiling point 215.5±35.0 °C(Predicted)
Density 1.362±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 13.16±0.10(Predicted)
Appearance Light yellow to yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2933399990

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T899093 (5-(trifluoromethyl)pyridin-2-yl)methanol 31181-84-7 50mg $45 2021-12-16 Buy
AK Scientific 3322AB (5-(Trifluoromethyl)pyridin-2-yl)methanol 31181-84-7 100mg $103 2021-12-16 Buy
Matrix Scientific 055505 [5-(Trifluoromethyl)-2-pyridinyl]methanol 95+% 31181-84-7 500mg $175 2021-12-16 Buy
Matrix Scientific 055505 [5-(Trifluoromethyl)-2-pyridinyl]methanol 95+% 31181-84-7 1g $195 2021-12-16 Buy
Apolloscientific PC200105 2-(Hydroxymethyl)-5-(trifluoromethyl)pyridine 31181-84-7 500mg $276 2021-12-16 Buy
Product number Packaging Price Buy
T899093 50mg $45 Buy
3322AB 100mg $103 Buy
055505 500mg $175 Buy
055505 1g $195 Buy
PC200105 500mg $276 Buy

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL Chemical Properties,Uses,Production

Synthesis

5-Trifluoromethyl-pyridine-2-carboxylic acid methyl ester

124236-37-9

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL

31181-84-7

IV. General procedure for the synthesis of 5-trifluoromethylpyridine-2-methanol: To a solution of methyl 5-trifluoromethylpyridine-2-carboxylate (2 g, 9.75 mmol) in methanol (30 mL) was added sodium borohydride (738 mg, 19.5 mmol) in one batch at 0 °C. The reaction mixture was stirred at room temperature for 2 hours and then concentrated. The residue was diluted with water (30 mL), acidified with 1N hydrochloric acid to pH ~5, and extracted with ethyl acetate (3 x 50 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated, and finally purified by silica gel column chromatography to afford 5-trifluoromethylpyridine-2-methanol as a colorless oil (1.6 g, 93% yield).1H NMR (400 MHz, CDCl3) δppm: 8.82 (s, 1H), 7.90-7.92 (m, 1H), 7.40-7.42 (m, 1H ), 4.82-4.83 (m, 2H), 3.44-3.46 (m, 1H); ES-LCMS m/z 178 ([M+H]+).

References

[1] Patent: WO2013/166621, 2013, A1. Location in patent: Page/Page column 48
[2] Patent: CN106831840, 2017, A. Location in patent: Paragraph 0102; 0103; 0104
[3] Patent: US2009/124666, 2009, A1. Location in patent: Page/Page column 25-26

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL Preparation Products And Raw materials

Global( 119)Suppliers
Supplier Tel Email Country ProdList Advantage
PNP Biotech Co. Ltd
+8618516098983 sales@pnpbiotech.com China 1001 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Hangzhou Cyanochem Co., Ltd.
+86 17788583750 sales@cyanochem.com CHINA 281 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49975 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29800 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23541 58

View Lastest Price from (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(5-(trifluoromethyl)pyridin-2-yl)methanol pictures 2024-03-28 (5-(trifluoromethyl)pyridin-2-yl)methanol
31181-84-7
US $0.00 / kg 25kg 98% Inquiry PNP Biotech Co. Ltd
(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL pictures 2021-08-31 (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL
31181-84-7
US $1.10 / g 1g 99.00% 100 Tons min Dideu Industries Group Limited
(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL pictures 2019-12-20 (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL
31181-84-7
US $1.00 / KG 1KG 99% Customized Career Henan Chemical Co

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL Spectrum

(5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL 2-(Hydroxymethyl)-5-(trifluoromethyl)pyridine 5-(trifluoromethyl)-2-Pyridinemethanol [5-(Trifluoromethyl)-2-pyridinyl]methanol 2-HydroxyMethyl-5-(TrifluorMethyl)-Pyridine 2-Pyridinemethanol, 5-(trifluoromethyl)- (5-TRIFLUOROMETHYL-PYRIDIN-2-YL) METHANOL ISO 9001:2015 REACH 31181-84-7