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2-Bromo-4-fluoroaniline

2-Bromo-4-fluoroaniline structure

CAS No.: 1003-98-1

Chemical Name:: 2-Bromo-4-fluoroaniline

Synonyms: 2-BROMO-4-FLUORO-PHENYLAMINE;Bromofluoroaniline1;2-Bromo-4-fluoroanil;4-FLUORO-2-BROMOANILINE;2-BROMO-4-FLUOROANILINE;2-Bromo-4-fluoroaniline99%;2-Bromo-4-fluoroaniline >2-Bromo-4-fluoroaniline 99%;2-BROMO-4-FLUOROANILINE 98+%;2-Bromo-4-fluoroaniline, 95%

CBNumber:: CB1402890

Molecular Formula:: C6H5BrFN

Molecular Weight:: 190.01

MDL Number:: MFCD00042462

MOL File:: 1003-98-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:33:43

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2-Bromo-4-fluoroaniline Properties

Melting point	41
Boiling point	221 °C (lit.)
Density	1.67 g/mL at 25 °C (lit.)
refractive index	n20/D 1.583(lit.)
Flash point	220 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	2.60±0.10(Predicted)
form	Liquid
color	Clear yellow-brown
Specific Gravity	1.670
BRN	2802562
InChI	InChI=1S/C6H5BrFN/c7-5-3-4(8)1-2-6(5)9/h1-3H,9H2
InChIKey	YLMFXCIATJJKQL-UHFFFAOYSA-N
SMILES	C1(N)=CC=C(F)C=C1Br
CAS DataBase Reference	1003-98-1(CAS DataBase Reference)
UNSPSC Code	12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xi,T

Risk Statements

36/37/38

Safety Statements

26-37/39

RIDADR

UN2810

WGK Germany

Hazard Note

Toxic

HazardClass

6.1

PackingGroup

III

HS Code

29214200

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		1

2-Bromo-4-fluoroaniline price More Price(50)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	369055	2-Bromo-4-fluoroaniline 97%	1003-98-1	5g	$25.2	2023-01-07	Buy
TCI Chemical	B1829	2-Bromo-4-fluoroaniline >98.0%(GC)	1003-98-1	5g	$24	2026-04-30	Buy
TCI Chemical	B1829	2-Bromo-4-fluoroaniline >98.0%(GC)	1003-98-1	25g	$76	2026-04-30	Buy
AstaTech	56016	2-BROMO-4-FLUORO-ANILINE 97%	1003-98-1	25G	$40	2026-04-30	Buy
Activate Scientific	AS40176	2-Bromo-4-fluoroaniline 98%	1003-98-1	25g	$39	2026-06-04	Buy

Product number	Packaging	Price	Buy
369055	5g	$25.2	Buy
B1829	5g	$24	Buy
B1829	25g	$76	Buy
56016	25G	$40	Buy
AS40176	25g	$39	Buy

2-Bromo-4-fluoroaniline Chemical Properties,Uses,Production

Uses

2-Bromo-4-fluoroaniline is an organic compound that is an aniline derivative. It is mainly used as an organic synthesis reagent in experimental research.

Chemical Properties

Clear yellow-brown liquid

General Description

2-Bromo-4-fluoroaniline is an aryl fluorinated building block.

Synthesis

371-40-4

1003-98-1

The general procedure for the synthesis of 2-bromo-4-fluoroaniline from 4-fluoroaniline was as follows: 200 mL of distilled N,N-dimethylformamide (DMF) and 4-fluoroaniline (8.64 mL, 58.13 mmol) were added to a two-necked flask equipped with a stirring device. N-bromosuccinimide (11.4 g, 63.95 mmol) dissolved in DMF was added slowly and dropwise with stirring. After completion of the reaction, extraction was carried out using dichloromethane (CH2Cl2). The product was purified by column chromatography (eluent ratio of ethyl acetate: n-hexane = 1:4), and the target product 2-bromo-4-fluoroaniline was finally obtained in 95% yield.

References

[1] Patent: KR2018/50795, 2018, A. Location in patent: Paragraph 0134; 0135; 0152-0154
[2] Tetrahedron Letters, 2000, vol. 41, # 13, p. 2083 - 2085
[3] Journal of the American Chemical Society, 2011, vol. 133, # 18, p. 6868 - 6870
[4] Chemistry - A European Journal, 2011, vol. 17, # 49, p. 13665 - 13669
[5] Tetrahedron Letters, 2014, vol. 55, # 38, p. 5338 - 5341

2-Bromo-4-fluoroaniline synthesis

Synthesis of 2-Bromo-4-fluoroaniline from 4-Fluoroaniline

2-Bromo-4-fluoroaniline Preparation Products And Raw materials

Raw materials

4-Fluoroaniline N,N-Dimethylformamide N-Bromosuccinimide

Preparation Products

5-Fluoro-2-methylindole 2-Amino-5-fluorophenyl boronic acid pinacol ester (2-Bromo-4-fluorophenyl)(methyl)sulfane 2-Amino-5-fluorobenzeneboronic acid 2-Bromo-4-fluoronitrobenzene

Methyl 8-bromo-6-fluoro-4-oxo-1,4-dihydroquinoline-2-carboxylate 4-Chloro-6-fluorocinnoline 4-fluoro-2-(2-phenylethynyl)phenylaMine tert-Butyl (2-bromo-4-fluorophenyl)carbamate

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2-Bromo-4-fluoroaniline Suppliers

Global( 502)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
HANGZHOU KINSOCHEM PHARMA CO.,LTD	0571-56950601,56950602 15957107654	951594434@qq.com	China	49	55
Shandong Zhishang Chemical Co. LTD	15689709505 15508639737	2138533552@qq.com	China	102	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
ShangHai DEMO Chemical Co.,Ltd	400-021-7337 2355568890	sales@demochem.com	China	2569	57
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Wuhan Chemwish Technology Co., Ltd	86-027-67849912	sales@chemwish.com	China	35884	56
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66

Supplier	Advantage
HANGZHOU KINSOCHEM PHARMA CO.,LTD	55
Shandong Zhishang Chemical Co. LTD	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
ShangHai DEMO Chemical Co.,Ltd	57
Energy Chemical	61
Wuhan Chemwish Technology Co., Ltd	56
Capot Chemical Co., Ltd	66

2-Bromo-4-fluoroaniline: Synthesis & Synthetic Applications
2-Bromo-4-fluoroaniline is a key fluorinated aromatic amine intermediate, synthesized from 4-fluoroaniline via bromination whi....
Mar 16,2026

View Lastest Price from 2-Bromo-4-fluoroaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-08	2-Bromo-4-fluoroaniline/4-FLUORO-2-BROMOANILINE 1003-98-1			99.0%MIN	15000KG	Hangzhou ICH Biofarm Co., Ltd
2026-05-28	2-Bromo-4-fluoroaniline 1003-98-1	$2.00-5.00	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD
2025-06-20	2-Bromo-4-fluoroaniline 1003-98-1	$40.00	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.

2-Bromo-4-fluoroaniline/4-FLUORO-2-BROMOANILINE
1003-98-1
$0.00
99.0%MIN
Hangzhou ICH Biofarm Co., Ltd

2-Bromo-4-fluoroaniline
1003-98-1
$2.00-5.00
99%
Hebei Chuanghai Biotechnology Co,.LTD

2-Bromo-4-fluoroaniline
1003-98-1
$40.00
0.99
Hebei Yanxi Chemical Co., Ltd.

2-Bromo-4-fluoroaniline Spectrum

2-Bromo-4-fluoroaniline(1003-98-1)MS 2-Bromo-4-fluoroaniline(1003-98-1)¹HNMR 2-Bromo-4-fluoroaniline(1003-98-1)¹³CNMR 2-Bromo-4-fluoroaniline(1003-98-1)IR1 2-Bromo-4-fluoroaniline(1003-98-1)Raman

1003-98-1(2-Bromo-4-fluoroaniline)Related Search:

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2-Bromo-4,6-difluoroaniline Bromine 2-Bromo-4,5,6-trifluoroaniline 2-Bromo-4,6-difluorophenyl isocyanate 2-Bromo-6-chloro-4-fluoroaniline

2,4,5-Trifluoro-6-bromoaniline 2-Bromo-4-fluorophenyl isothiocyanate 2,6-Dibromo-4-fluorophenyl isocyanate

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4-FLUORO-2-BROMOANILINE 2-BROMO-4-FLUOROANILINE 98+% Bromofluoroaniline1 2-Bromo-4-fluoroaniline 99% 2-Bromo-4-fluoroaniline99% 2-BROMO-4-FLUOROANILINE 2-Bromo-4-fluoroanil Benzenamine, 2-bromo-4-fluoro- 2 - broMine - 4 - fluoro aniline 2-Bromo-4-fluoroaniline > 2-Bromo-4-fluoroaniline ISO 9001：2015 REACH TIANFU-CHEM 2-Bromo-4-fluoroaniline 4-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-74-THIOSEMICARBAZIDE 2-Bromo-4-fluoroaniline/4-FLUORO-2-BROMOANILINE 2-Bromo-4-fluoroaniline, 95% 2-BROMO-4-FLUORO-PHENYLAMINE 1003-98-1 C2 to C6 Amines Building Blocks Organic Building Blocks Nitrogen Compounds amine| alkyl Fluorine| alkyl bromide Pyridines Miscellaneous Anilines, Amides & Amines Bromine Compounds Fluorine Compounds Amines C2 to C6 Nitrogen Compounds Anilines, Aromatic Amines and Nitro Compounds Fluorobenzene 1003-98-1