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6-Aminopenicillanic acid

6-Aminopenicillanic acid structure

CAS No.: 551-16-6

Chemical Name:: 6-Aminopenicillanic acid

Synonyms: 6-APA;penin;Amoxicillin EP Impurity A;AMoxicillin Related CoMpound A;6-amino penicillanic acid(6-APA);6-Amino;Flucloxacillin EP Impurity C;6-AMINO-2,2-DIMETHYL-5-OXOPERHYDROAZETO[2,1-B][1,3]THIAZOLE-3-CARBOXYLIC ACID;6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID;Amoxicillin Related Compound A (15 mg) ((2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid)

CBNumber:: CB1410046

Molecular Formula:: C8H12N2O3S

Molecular Weight:: 216.26

MDL Number:: MFCD00005176

MOL File:: 551-16-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:34:41

Product description	Number	Pack Size	Price
Flucloxacillin impurity C European Pharmacopoeia (EP) Reference Standard	Y0000889	5 mg	$244
Amoxicillin Related Compound A	PHR2188	50MG	$593
Amoxicillin Related Compound A United States Pharmacopeia (USP) Reference Standard	1031514	15mg	$1390
(+)-6-Aminopenicillanic acid analytical standard	07307	100mg	$85.9
6-Aminopenicillanic Acid >98.0%(HPLC)	A0800	5g	$17
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6-Aminopenicillanic acid Properties

Melting point	198-200 °C (dec.)(lit.)
alpha	276.3 º (c=1.2, 0.1N HCl 22 ºC)
Boiling point	460.2±45.0 °C(Predicted)
Density	1.3418 (rough estimate)
refractive index	1.6300 (estimate)
storage temp.	2-8°C
solubility	2.46g/l
pka	pKa 2.3 (Uncertain)
form	Fine Powder
color	White to cream
PH	3.4 (100g/l, H2O)
optical activity	[α]22/D +276.3°, c = 1.2 in 0.1 M HCl
Water Solubility	Soluble in water and hydrochoric acid.
Merck	14,458
BRN	15080
Stability	Light sensitive
InChI	1S/C8H12N2O3S/c1-8(2)4(7(12)13)10-5(11)3(9)6(10)14-8/h3-4,6H,9H2,1-2H3,(H,12,13)/t3-,4+,6-/m1/s1
InChIKey	NGHVIOIJCVXTGV-SDKNWNMFSA-N
SMILES	CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(O)=O
LogP	-3.87 at 22.5℃
CAS DataBase Reference	551-16-6(CAS DataBase Reference)
FDA UNII	QR0C4R7XVN
EPA Substance Registry System	6-Aminopenicillanic acid (551-16-6)
UNSPSC Code	77101502
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

P264-P280-P305+P351+P338-P337+P313

PPE

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes

Risk Statements

42/43

Safety Statements

22-36/37-45-37-24-36

WGK Germany

RTECS

XH8225000

TSCA

TSCA listed

HS Code

29349990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2

REACH Registrations

Active

NFPA 704

	0
2		0

6-Aminopenicillanic acid price More Price(89)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	Y0000889	Flucloxacillin impurity C European Pharmacopoeia (EP) Reference Standard	551-16-6	5 mg	$244	2026-04-30	Buy
Sigma-Aldrich	PHR2188	Amoxicillin Related Compound A	551-16-6	50MG	$593	2026-04-30	Buy
Sigma-Aldrich	1031514	Amoxicillin Related Compound A United States Pharmacopeia (USP) Reference Standard	551-16-6	15mg	$1390	2026-04-30	Buy
Sigma-Aldrich	07307	(+)-6-Aminopenicillanic acid analytical standard	551-16-6	100mg	$85.9	2026-04-30	Buy
TCI Chemical	A0800	6-Aminopenicillanic Acid >98.0%(HPLC)	551-16-6	5g	$17	2026-04-30	Buy

Product number	Packaging	Price	Buy
Y0000889	5 mg	$244	Buy
PHR2188	50MG	$593	Buy
1031514	15mg	$1390	Buy
07307	100mg	$85.9	Buy
A0800	5g	$17	Buy

6-Aminopenicillanic acid Chemical Properties,Uses,Production

Chemical Properties

WHITE TO CREAM FINE POWDER

Uses

(+)-6-Aminopenicillanic Acid is the core structure in penicillins, obtained from the fermentation brew of the Penicillium mold. (+)-6-Aminopenicillanic Acid is used as the main starting block for the preparation of numerous semisynthetic penicillins.

Uses

6-Aminopenicillanic acid is the basic unit in penicillins, which is obtained from the fermentation brew of the Penicillium mold. It acts as a starting material for the preparation of many semisynthetic penicillins. Further, it serves as apharmaceutical intermediate. In addition to this, it is used in antibiotics research and experimental application.

Definition

ChEBI: A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and ph rmacologic characteristics.

General Description

Chemical structure: -lactam

Flammability and Explosibility

Non flammable

Safety Profile

Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Purification Methods

This acid crystallises from water. [Kleppe & Stroninger J Biol Chem 254 4856 1979,Beilstein 27 III/IV 2858.]

6-Aminopenicillanic acid Preparation Products And Raw materials

Raw materials

Ampicillin Bis(2-dimethylaminoethyl) ether Imine Penicillin G potassium salt Ampicillin trihydrate

Ammonium bicarbonate

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Preparation Products

Piperacillin CARBENICILLIN Penicillin G Primaxin monohydrate Oxacillin sodium monohydrate

Flucloxacillin sodium [2S-(2alpha,5alpha,6alpha)]-6-bromo-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (3S)-6,6-DIBROMO-2,2-DIMETHYLPENAM-3-CARBOXYLIC ACID 1,1-DIOXIDE methicillin

4-Thiazolecarboxylic acid 6β-Phthalimidopenicillanic Acid

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6-Aminopenicillanic acid Suppliers

Global( 579)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	+8615350571055	Sibel@chuanghaibio.com	China	8738	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5228	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	1006	58
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Hebei Ganmiao New material Technology Co., LTD	+86-17332992504	sales8@hbganmiao.com	China	300	58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.	+86-18600796368	sales@sjar-tech.com	China	529	58
Moxin Chemicals	+86-17320513646 +8617320513646	anna@molcoo.com	China	10000	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21587	55

Supplier	Advantage
Hebei Chuanghai Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Hangzhou ICH Biofarm Co., Ltd	58
airuikechemical co., ltd.	58
Hebei Ganmiao New material Technology Co., LTD	58
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.	58
Moxin Chemicals	58
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from 6-Aminopenicillanic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-06-05	6-Aminopenicillanic acid 551-16-6		1KG	99%	10 TONS	WUHAN FORTUNA CHEMICAL CO., LTD
2026-06-05	6-Aminopenicillanic acid 551-16-6			0.99		RongNa Biotechnology Co.,Ltd
2026-05-28	6-Aminopenicillanic acid 551-16-6	$9.00	1KG	99.9	1 ton	Hebei Chuanghai Biotechnology Co,.LTD

6-Aminopenicillanic acid
551-16-6
99%
WUHAN FORTUNA CHEMICAL CO., LTD

6-Aminopenicillanic acid
551-16-6
0.99
RongNa Biotechnology Co.,Ltd

6-Aminopenicillanic acid
551-16-6
$9.00
99.9
Hebei Chuanghai Biotechnology Co,.LTD

6-Aminopenicillanic acid Spectrum

6-Aminopenicillanic acid(551-16-6)MS 6-Aminopenicillanic acid(551-16-6)IR1 6-Aminopenicillanic acid(551-16-6)IR2 6-Aminopenicillanic acid(551-16-6)Raman

551-16-6(6-Aminopenicillanic acid)Related Search:

Dimethyl ether Dimethyl fumarate ETHANE EC 2.6.1.2 6-Aminocaproic acid

Acetaminophen 2-(2-Aminothiazol-4-yl)glyoxylic acid N,N-Dimethyl-1,4-phenylenediamine Dicloxacillin sodium Heptane

Glucosamine Ethyl 2-(Chlorosulfonyl)acetate 12-AMINODODECANOIC ACID Dimethyl carbonate Sodium 1-heptanesulfonate

Dimethyl sulfoxide N,N-Dimethylformamide Methyl 6-aminonicotinate

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6-AMINO-2,2-DIMETHYL-5-OXOPERHYDROAZETO[2,1-B][1,3]THIAZOLE-3-CARBOXYLIC ACID 6-AMINOPENICILLANIC ACID 6-AMINO PENICILLINIC ACID 7-AMINO-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID (25,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID (2S,5R,6R)-6-AMINO-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO-[3.2.0]HEPTANE-2-CARBOXYLIC ACID aminopenicillanicacid penicin phenacyl6-aminopenicillinate 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-amino-3,3-dimethyl-7-oxo-, [2S-(2alpha,5alpha,6beta)]- 6-Aminopenicillanic acid;6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-APA 6-amino penicillanic acid(6-APA) 6-Aminopenicillanicacid,98% 6-Amino 6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid 98% 6-Aminopenicillansure 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-amino-3,3-dimethyl-7-oxo-,[2S-(2.alpha.,5.alpha.,6.beta.)] 6-AMINOPENICILLANIC ACID 99% (2S,5R,6R)-6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid 98% (2S,5R,6R)-6-Amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1,3]thiazole-3-carboxylic acid AMoxicillin IMpurity A (SulbactaM IMpurity B) Piperacillin IMpurity H (+)-6-Aminopenicillanic acid, >=99.0% Penicillan intermediate: penicillan core 6-Aminopenicillanic acid for synthesis Amoxicillin EP Impurity A(Sulbactam EP Impurity B) (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-APA 6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 6-amino-2,2-dimethyl-5-oxoperhydroazeto[2,1-b][1 Sulbactam impurity B 6-aminopenicilanic acid(6-APA) Cloxacillin Impurity 3(Cloxacillin EP Impurity C) Dicloxacillin Impurity 3(Dicloxacillin EP Impurity C) Flucloxacillin Impurity 3(Flucloxacillin EP Impurity C) Piperacillin Impurity 8(EP Impurity H) Sulbactam Impurity 2(Sulbactam EP Impurity B) Ampicillin Impurity 1（Ampicillin EP Impurity A） Piperacillin Sodium EP Impurity H Phenoxymethylpenicillin Impurity 3（Phenoxymethylpenicillin EP Impurity C） Amoxicillin Impurity 1（EP Impurity A） (2S,5R,6R)-(+)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 97% Benzylpenicillin Impurity 1（Benzylpenicillin EP Impurity A) 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-amino-3,3-dimethyl-7-oxo 5alpha,6beta)]-[2s-(2alpha 6-amino-3,3-dimethyl-7-oxo-,[2S-(2.alpha.,5.alpha.,6.beta.)]-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid 6-aps 6-APA, (2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-amino-3,3-dimethyl-7-oxo-, (2S,5R,6R)- (2S,5β)-6α-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid (2β,5β)-6α-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2β-carboxylic acid (6R)-6-Aminopenicillanic acid 6-Aminopenicillanic acid,96% 6-AMinopenicillanic acid, 96% 25GR [2S-(2α,5α,6β)]-6-AMino-3,3-diMethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid NSC 50071 4-AMino-5-nitroso-2,6-pyriMidinediol-13C2 5-Nitroso-6-aMinouracil-13C2 6-AMino-5-nitroso-2,4(1H,3H)-pyriMidinedione-13C2 6-AMino-5-nitroso-2,4-pyriMidinediol-13C2 6-AMino-5-nitroso-22,4(1H,3H)-pyriMidinedione-13C2