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trans-4-Hydroxy-D-proline

trans-4-Hydroxy-D-proline structure

CAS No.: 3398-22-9

Chemical Name:: trans-4-Hydroxy-D-proline

Synonyms: (2R,4S)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID;H-D-HYP-OH;D-Hyp-OH;H-D-Hyp-OH.HCL;D-HYDROXYPROLINE;D-HYDROXYPYROLINE;In1122 Impurity 57;D-hydroxyl proline;D-trans-Hydroxyproli;H-D-PRO(4-HYDROXY)-OH

CBNumber:: CB1411629

Molecular Formula:: C5H9NO3

Molecular Weight:: 131.13

MDL Number:: MFCD00065608

MOL File:: 3398-22-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:12

Product description	Number	Pack Size	Price
trans-4-Hydroxy-D-proline 97%	702501	250mg	$93.8
trans-4-Hydroxy-D-proline 97%	702501	1g	$178
(4S)-4-Hydroxy-D-proline	H1757	250MG	$45
(4S)-4-Hydroxy-D-proline	H1757	1G	$112
trans-D-4-Hydroxyproline	279899	500mg	$368
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trans-4-Hydroxy-D-proline Properties

Melting point	260°C
Boiling point	355.2±42.0 °C(Predicted)
Density	1.395±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	2.14±0.40(Predicted)
form	powder
color	White to off-white
Major Application	peptide synthesis
InChI	InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m0/s1
InChIKey	PMMYEEVYMWASQN-IUYQGCFVSA-N
SMILES	C(O)(=O)[C@H]1C[C@H](O)CN1
CAS DataBase Reference	3398-22-9(CAS DataBase Reference)
UNSPSC Code	12352209
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS08

Signal word

Danger

Hazard statements

H302-H315-H319-H334-H335

Precautionary statements

P301+P312+P330-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hazard Codes

Risk Statements

22-36/37/38-43

Safety Statements

24/25-36/37-26

WGK Germany

HS Code

29339900

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Resp. Sens. 1
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
0		0

trans-4-Hydroxy-D-proline price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	702501	trans-4-Hydroxy-D-proline 97%	3398-22-9	250mg	$93.8	2023-06-20	Buy
Sigma-Aldrich	702501	trans-4-Hydroxy-D-proline 97%	3398-22-9	1g	$178	2023-06-20	Buy
TCI Chemical	H1757	(4S)-4-Hydroxy-D-proline	3398-22-9	250MG	$45	2026-04-30	Buy
TCI Chemical	H1757	(4S)-4-Hydroxy-D-proline	3398-22-9	1G	$112	2026-04-30	Buy
Usbiological	279899	trans-D-4-Hydroxyproline	3398-22-9	500mg	$368	2021-12-16	Buy

Product number	Packaging	Price	Buy
702501	250mg	$93.8	Buy
702501	1g	$178	Buy
H1757	250MG	$45	Buy
H1757	1G	$112	Buy
279899	500mg	$368	Buy

trans-4-Hydroxy-D-proline Chemical Properties,Uses,Production

Chemical Properties

White to pale pink solid

Uses

peptide synthesis

Definition

ChEBI: Trans-4-hydroxy-D-proline is a 4-hydroxy-D-proline in which the hydroxy group at position 4 has S-configuration.

reaction suitability

reaction type: solution phase peptide synthesis

trans-4-Hydroxy-D-proline synthesis

Synthesis of trans-4-Hydroxy-D-proline from D-Proline, 4-hydroxy-, (4S)-rel-

trans-4-Hydroxy-D-proline Preparation Products And Raw materials

Raw materials

D-Proline, 1-acetyl-4-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, cis- (9CI) D-Proline, 4-hydroxy-, (4S)-rel- L-Hydroxyproline

Preparation Products

(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID (2S,4R)-Methyl 4-hydroxypyrrolidine-2-carboxylate D-Proline, 4-hydroxy-, methyl ester, (4S)- (9CI)

trans-4-Hydroxy-D-proline Suppliers

Global( 232)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-173 9270 1263	1057@dideu.com	China	4000	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Chengdu Pukang Biotechnology Co., Ltd	028-82550498	export@pu-kang.com	CHINA	210	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2176	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Capot Chemical Co.,Ltd.	60
Chembon Pharmaceutical Co., Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Chengdu Pukang Biotechnology Co., Ltd	58
Changzhou Ditong Chemical Co.,Ltd	58
BOC Sciences	58

The uses of trans-4-Hydroxy-D-proline
Trans-4-hydroxy-D-proline is a 4-hydroxy-D-proline in which the hydroxy group at position 4 has S-configuration. The method w....
Jan 9，2020

View Lastest Price from trans-4-Hydroxy-D-proline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	trans-4-Hydroxy-D-proline 3398-22-9	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2024-07-20	trans-4-Hydroxy-D-proline 3398-22-9	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd
2024-04-23	trans-4-Hydroxy-D-proline 3398-22-9	US $1.00 / g	1g	99%	10 tons	ANHUI WITOP BIOTECH CO., LTD

trans-4-Hydroxy-D-proline
3398-22-9
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

trans-4-Hydroxy-D-proline
3398-22-9
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

trans-4-Hydroxy-D-proline
3398-22-9
US $1.00 / g
99%
ANHUI WITOP BIOTECH CO., LTD

trans-4-Hydroxy-D-proline Spectrum

trans-4-Hydroxy-D-proline(3398-22-9)¹HNMR trans-4-Hydroxy-D-proline(3398-22-9)¹³CNMR

3398-22-9(trans-4-Hydroxy-D-proline)Related Search:

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N-Cbz-Hydroxy-L-proline Boc-Hyp-OH D-Proline

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TRANS-D-HYDROXYPROLINE TRANS-D-4-HYDROXYPROLINE TRANS-4-HYDROXY-D-PROLINE (2R,4S)-(-)-4-HYDROXY-2-PYRROLINECARBOXYLIC ACID (2R,4S)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID H-D-PRO(4-HYDROXY)-OH H-D-PRO(TRANS-4-HYDROXY)-OH H-D-HYP-OH D-HYDROXYPROLINE trans-4-D-Hydroxyproline trans-4-Hydroxy-D-proline,(2R,4S)-4-Hydroxypyrrolidine-2-carboxylic acid trans-D-Hydroxyproline, (2R,4S)-(-)-4-Hydroxy-2-pyrrolinecarboxylic acid D-HYDROXYPYROLINE D-trans-Hydroxyproli 4-hydroxypyrrolidine-2-carboxylic acid HCL In1122 Impurity 57 H-D-Hyp-OH.HCL D-Proline, 4-hydroxy-,(4S)- trans-4-Hydroxy-D-proline 97% trans-4-Hydroxy-D-proline, (4S)-4-Hydroxy-D-proline (R)-1-hydroxypyrrolidine-2-carboxylic acid trans-4-Hydroxy-D-proline D-Hyp-OH trans-D-4-Hydroxyproline≥ 99% (HPLC) tratrans-4-Hydroxy-D-prolinens-4-Hydroxy-D-proline trans-4-Hydroxy-D-proL (4S)-4-Hydroxy-D-proline 2-Naphthalenesulfonylchloride,5,6,7,13-tetrahydro- (2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid/trans-4-hydroxy-D-proline (2R,4S)-trans-4-hydroxy-D-proline D-hydroxyl proline 3398-22-9 98-22-9 C5HNO3 Carboxylic Acids Pyrrolidines Chiral Compound Carboxylic Acids