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Pregnenolone acetate

CAS No.
1778-02-5
Chemical Name:
Pregnenolone acetate
Synonyms
Artivis;Enescorb;Sharmone;Previsone;NSC 64827;ACETOXYPREGNENOLONE;Pregenolone acetate;PREGNENOLONE ACETATE;prognenolone acetate;5-Pregnenolone acetate
CBNumber:
CB1411937
Molecular Formula:
C23H34O3
Molecular Weight:
358.51
MDL Number:
MFCD00003627
MOL File:
1778-02-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

Pregnenolone acetate Properties

Melting point 149-152 °C(lit.)
alpha 22 º (c=2, C2H5OH 23 ºC)
Boiling point 430.93°C (rough estimate)
Density 1.0816 (rough estimate)
refractive index 1.4700 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Solid
color White
optical activity [α]20/D +19°, c = 1 in ethanol
Merck 14,7733
BRN 2062850
Cosmetics Ingredients Functions SKIN CONDITIONING
InChI 1S/C23H34O3/c1-14(24)19-7-8-20-18-6-5-16-13-17(26-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h5,17-21H,6-13H2,1-4H3/t17-,18-,19+,20-,21-,22-,23+/m0/s1
InChIKey CRRKVZVYZQXICQ-RJJCNJEVSA-N
SMILES CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@H]4C(C)=O)[C@@H]3CC=C2C1
CAS DataBase Reference 1778-02-5(CAS DataBase Reference)
EWG's Food Scores 1-3
FDA UNII 0G0WWV404B
NIST Chemistry Reference 3Beta-acetoxypregn-5-en-20-one(1778-02-5)
UNSPSC Code 12352108
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
HS Code  29153900
Storage Class 11 - Combustible Solids
REACH Registrations Active

Pregnenolone acetate price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P49902 Pregnenolone acetate 99% 1778-02-5 25g $298 2026-04-30 Buy
Sigma-Aldrich P49902 Pregnenolone acetate 99% 1778-02-5 5g $58.1 2023-06-20 Buy
TCI Chemical P0477 Pregnenolone Acetate >99.0%(HPLC) 1778-02-5 1g $27 2026-04-30 Buy
TCI Chemical P0477 Pregnenolone Acetate >99.0%(HPLC) 1778-02-5 10g $87 2026-04-30 Buy
TRC TRC-P712210-25G Pregnenolone Acetate 1778-02-5 25g $135 2026-06-03 Buy
Product number Packaging Price Buy
P49902 25g $298 Buy
P49902 5g $58.1 Buy
P0477 1g $27 Buy
P0477 10g $87 Buy
TRC-P712210-25G 25g $135 Buy

Pregnenolone acetate Chemical Properties, Uses, Production

Chemical Properties

white to light yellow crystalline powder or Crystallized (methanol).

Uses

Pregnenolone acetate is an intermediate in the synthesis of progesterone. It is uses as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It has also been shown to stimulate locomotor activity and neuronal function in rats.

Preparation

Pregnenolone acetate can be prepared by catalytic hydrogenation (16-position double bond) of 16-Dehydropregnenolone acetate.

Definition

Pregnenolone acetate is a steroid ester. It is a pregnenolone derivative, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.

145-13-1
75-36-5
1778-02-5
Synthesis of Pregnenolone acetate from Pregnenolone and Acetyl chloride

Pregnenolone acetate Preparation Products And Raw materials

Global Suppliers ( 291)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
XiaoGan ShenYuan ChemPharm co,ltd 15527621225; 15527621225 1791901229@qq.com China 6735 52
ChemCell Biomedicine Co.,Ltd. 020-13556033878 2965585218 13556033878 chemcell@hotmail.com China 369 52
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57

View Latest Price from Pregnenolone acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pregnenolone acetate pictures 2026-09-24 Pregnenolone acetate
1778-02-5
1KG 97%-103% 500kg WUHAN FORTUNA CHEMICAL CO., LTD
Pregnenolone acetate pictures 2026-08-25 Pregnenolone acetate
1778-02-5
1kg 99% 888kgs Xi an Biohorlden Industry Trade Co Ltd
Pregnenolone Acetate pictures 2026-08-25 Pregnenolone Acetate
1778-02-5
1KG 0.99 1000KG Shaanxi Xianhe Biotech Co., Ltd
17-ACETYL-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE 3 BETA,21-DIHYDROXY-5-PREGNEN-20-ONE-3-ACETATE 3-BETA-HYDROXY-5-PREGNEN-20-ONE 3-ACETATE 3BETA-ACETOXY-5-PREGNEN-20-ONE ACETIC ACID (3S,8S,9S,10R,13S,14S,17S)-17-ACETYL-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ESTER ACETOXYPREGNENOLONE 5-PREGNEN-3BETA-OL-20-ONE 3-ACETATE 5-PREGNEN-3BETA-OL-20-ONE ACETATE 20-Oxopregn-5-en-3beta-yl acetate 20-Oxopregn-5-en-3-yl acetate 5-Allopregnene-3beta-ol-20-one acetate 5-Pregnenolone acetate Artivis Enescorb Pregenolone acetate 20-OXOPREGN-5-EN-3B-YL ACETATE PREGNENOLONE ACETATE acetic acid [(13S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester 3β-acetoxy-5-pregnen-20-one 3B-Hydroxy-5-pregnen-20-one acetate 21-hydroxypregnenolone 3-acetate Pregn-5-en-20-one, 3-(acetyloxy)-, (3beta)- Pregn-5-en-20-one, 3beta-hydroxy-, acetate Pregnenolone-3-acetate Previsone Sharmone 5-Pregnen-3β-ol-20-one acetate 3β-Acetoxy-5-pregnen-20-one, 5-Pregnen-3β-ol-20-one acetate [(3S,8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate 3β-Acetoxypregn-5-en-20-one 3β-Acetyloxypregn-5-en-20-one Pregnenolone acetate,99% Pregnenolone acetate3beta-Acetoxy-5-pregnen-20-one Pregnenolone acetate,3β-Acetoxy-5-pregnen-20-one, 5-Pregnen-3β-ol-20-one acetate 3β,21-Dihydroxy-5-pregnen-20-one 3-acetate 3β-Acetoxy-21-hydroxy-5-pregnen-20-one 3β-Hydroxy-5-pregnen-20-one 3-acetate prognenolone acetate Pregnenolone acetate 99% (3β)-3-(Acetyloxy)-pregn-5-en-20-one 3β-Hydroxypregn-5-en-20-one Acetate 3β-Pregn-5-enol-20-one Acetate 5-Pregnene-3β-acetoxy-20-one NSC 64827 3beta,21-dihydroxy-5-pregen-20-one-3-acetate PregnenoloneAcetate> Pregn-5-en-20-one, 3-(acetyloxy)-, (3β)- 17-ACETYL-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H- Methylene pyridine hydrogenation product 3β-acetoxy-pregn-5-en-20-one 5-PREGNEN-3β-OL-20-ONE ACETATE (3S,8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate 16-Dehydropregnenolone acetate Impurity 3 Pregnenolone acetate 1778-02-5 778-02-5 1778-02-2 Ce3H34O3 C23H34O3