Pregnenolone acetate
- CAS No.
- 1778-02-5
- Chemical Name:
- Pregnenolone acetate
- Synonyms
- Artivis;Enescorb;Sharmone;Previsone;NSC 64827;ACETOXYPREGNENOLONE;Pregenolone acetate;PREGNENOLONE ACETATE;prognenolone acetate;5-Pregnenolone acetate
- CBNumber:
- CB1411937
- Molecular Formula:
- C23H34O3
- Molecular Weight:
- 358.51
- MDL Number:
- MFCD00003627
- MOL File:
- 1778-02-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 149-152 °C(lit.) |
|---|---|
| alpha | 22 º (c=2, C2H5OH 23 ºC) |
| Boiling point | 430.93°C (rough estimate) |
| Density | 1.0816 (rough estimate) |
| refractive index | 1.4700 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White |
| optical activity | [α]20/D +19°, c = 1 in ethanol |
| Merck | 14,7733 |
| BRN | 2062850 |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChI | 1S/C23H34O3/c1-14(24)19-7-8-20-18-6-5-16-13-17(26-15(2)25)9-11-22(16,3)21(18)10-12-23(19,20)4/h5,17-21H,6-13H2,1-4H3/t17-,18-,19+,20-,21-,22-,23+/m0/s1 |
| InChIKey | CRRKVZVYZQXICQ-RJJCNJEVSA-N |
| SMILES | CC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@H]4C(C)=O)[C@@H]3CC=C2C1 |
| CAS DataBase Reference | 1778-02-5(CAS DataBase Reference) |
| EWG's Food Scores | 1-3 |
| FDA UNII | 0G0WWV404B |
| NIST Chemistry Reference | 3Beta-acetoxypregn-5-en-20-one(1778-02-5) |
| UNSPSC Code | 12352108 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| PPE | Eyeshields, Gloves, type N95 (US) |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HS Code | 29153900 |
| Storage Class | 11 - Combustible Solids |
| REACH Registrations | Active |
Pregnenolone acetate price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P49902 | Pregnenolone acetate 99% | 1778-02-5 | 25g | $298 | 2026-04-30 | Buy |
| Sigma-Aldrich | P49902 | Pregnenolone acetate 99% | 1778-02-5 | 5g | $58.1 | 2023-06-20 | Buy |
| TCI Chemical | P0477 | Pregnenolone Acetate >99.0%(HPLC) | 1778-02-5 | 1g | $27 | 2026-04-30 | Buy |
| TCI Chemical | P0477 | Pregnenolone Acetate >99.0%(HPLC) | 1778-02-5 | 10g | $87 | 2026-04-30 | Buy |
| TRC | TRC-P712210-25G | Pregnenolone Acetate | 1778-02-5 | 25g | $135 | 2026-06-03 | Buy |
Pregnenolone acetate Chemical Properties, Uses, Production
Chemical Properties
white to light yellow crystalline powder or Crystallized (methanol).
Uses
Pregnenolone acetate is an intermediate in the synthesis of progesterone. It is uses as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It has also been shown to stimulate locomotor activity and neuronal function in rats.
Preparation
Pregnenolone acetate can be prepared by catalytic hydrogenation (16-position double bond) of 16-Dehydropregnenolone acetate.
Definition
Pregnenolone acetate is a steroid ester. It is a pregnenolone derivative, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.
Pregnenolone acetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6735 | 52 |
| ChemCell Biomedicine Co.,Ltd. | 020-13556033878 2965585218 13556033878 | chemcell@hotmail.com | China | 369 | 52 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
View Latest Price from Pregnenolone acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![]() |
2026-09-24 | Pregnenolone acetate
1778-02-5
|
1KG | 97%-103% | 500kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
![]() |
2026-08-25 | Pregnenolone acetate
1778-02-5
|
1kg | 99% | 888kgs | Xi an Biohorlden Industry Trade Co Ltd | ||
![]() |
2026-08-25 | Pregnenolone Acetate
1778-02-5
|
1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd |
-

- Pregnenolone acetate
1778-02-5
- 97%-103%
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Pregnenolone acetate
1778-02-5
- $0.00
- 99%
- Xi an Biohorlden Industry Trade Co Ltd
-

- Pregnenolone Acetate
1778-02-5
- $0.00
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
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