ELEUTHEROSIDE A
- CAS No.
- 474-58-8
- Chemical Name:
- ELEUTHEROSIDE A
- Synonyms
- DAUCOSTEROL;SITOGLUSIDE;ALEXANDRIN;lyoniside;β-sitosterol-3-O-β-D-glucopyranoside;daucosterin;Β-SITOSTEROL Β-D-GLUCOSIDE;Carrot glycoside;3-beta-(beta-d-glucopyranosyloxy)-stigmast-5-en;BSSG
- CBNumber:
- CB1412792
- Molecular Formula:
- C35H60O6
- Molecular Weight:
- 576.86
- MDL Number:
- MFCD01683621
- MOL File:
- 474-58-8.mol
| Product description | Number | Pack Size | Price |
| β-Sitosterol β-D-glucoside analytical standard | 89851 | 10mg | $789 |
| β-Sitosterol β-D-glucoside | S497010 | 25mg | $275 |
| Eleutheroside A | 300212 | 20mg | $390 |
| β-itosterolβ-D-glucoside | 107239 | 10mg | $525 |
| Eleutheroside A >98%,Standard References Grade | orb104914 | 20mg | $569.5 |
| More product size | |||
| Melting point | 283~286℃ |
|---|---|
| Boiling point | 673.6±55.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| Flash point | 361℃ |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly,Heated), Pyridine (Slightly, Sonicated) |
| pka | 12.91±0.70(Predicted) |
| form | Solid |
| color | Off-White to Pale Beige |
| Major Application | food and beverages |
| InChIKey | YITHQYDRZAVJHB-WWJUBMRMSA-N |
| SMILES | CC[C@H](CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](CC[C@]4(C)[C@H]3CC[C@]12C)O[C@@H]5OC(CO)[C@@H](O)[C@H](O)C5O)C(C)C |
| LogP | 8.615 (est) |
| FDA UNII | U45VN859W3 |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29389090 |
| Storage Class | 11 - Combustible Solids |
| Toxicity | LD50 intraperitoneal in mouse: 62mg/kg |
ELEUTHEROSIDE A price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 89851 | β-Sitosterol β-D-glucoside analytical standard | 474-58-8 | 10mg | $789 | 2025-07-31 | Buy |
| TRC | S497010 | β-Sitosterol β-D-glucoside | 474-58-8 | 25mg | $275 | 2021-12-16 | Buy |
| Usbiological | 300212 | Eleutheroside A | 474-58-8 | 20mg | $390 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 107239 | β-itosterolβ-D-glucoside | 474-58-8 | 10mg | $525 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb104914 | Eleutheroside A >98%,Standard References Grade | 474-58-8 | 20mg | $569.5 | 2021-12-16 | Buy |
ELEUTHEROSIDE A Chemical Properties,Uses,Production
Uses
Daucosterol can be used as an efficient and inexpensive neuroprotectants, to which the IGF1-like activity of daucosterol contributes and it could be potentially developed as a medicine for ischemic stroke treatment. Moreover, daucosterol has neuroprotective activity, it has proliferation-enhancing activity of neural stem cells (NSCs), and it as an efficient and inexpensive growth factor alternative that could be potentially developed as a medicine for ischemic stroke treatment, can significantly reduce neuronal loss.
The study demonstrated that daucosterol works as an efficient and inexpensive growth factor alternative that could be used in clinical medicine and research applications.
Description
Daucosterol, alias: Citoside, β-Sitosterol β-D-glucoside, and the molecular formula is C35H6. The compound of the formula (description column) belongs to a carotene compound, which is present in mallow family plants, and figs and other plants also contain carotene. Daucosterol exhibits anti-tumor, anti-inflammatory and acaricidal activities, also moderate antibacterial activity against Bacillus subtilis and Staphylococcus aureus, and it has anti-cancer and apoptotic effects in human colon cancer cell line HCT-116.
Chemical Properties
White to off white powder
Uses
β-Sitosterol and β-sitosteryl-β-D-glucoside were isolated as analgesic constituents from the leaves of Mentha cordifolia Opiz.
Definition
ChEBI: A steroid saponin that is sitosterol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It has bee isolated from Panax japonicus var. major and Breynia fruti osa.
Synthesis
2280-44-6
83-46-5
474-58-8
β-sitosterol (124.4 g, 0.3 mol) and D-glucose (18.0 g, 0.1 mol) were dissolved in ethylbenzene (600 mL). Trimethylsilyl trifluoromethanesulfonate (TMSOTf, 8.9 g, 7.3 mL, 40 mmol) was slowly added to the reaction system at 80 °C and the reaction was continued at a constant temperature until thin-layer chromatography (TLC) detection showed that the D-glucose was almost completely consumed (about 15 h). Upon completion of the reaction, the reaction solution was concentrated and subsequently separated by silica gel column chromatography using dichloromethane as eluent (silica gel particle size 100-200 mesh). The separation was monitored by TLC until β-sitosterol was no longer detected in the eluate, and the corresponding eluate was collected and concentrated to give the recovered β-sitosterol (83.0 g, 0.2 mol). The elution was continued with ethyl acetate as eluent and monitored by TLC until the target product (2R,3R,4S,5S,6R)-2-((3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethyl-2,3, 4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Concentration of the eluate containing the target product gave a white solid product (47.3 g) in 82% yield and 97.8% purity as determined by high performance liquid chromatography (HPLC).
in vivo
Daucosterol (0.5-2.5 mg/kg, p.o., once per day for 7 days) significantly inhibits the H22 tumor growth in ICR mice inoculated with H22 hepatoma cells[1].
References
[1] Patent: CN104693266, 2018, B. Location in patent: Paragraph 0062-0064
ELEUTHEROSIDE A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3589 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21595 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253; +8618283602253 | jancyzheng@gcgreenpure.com | China | 954 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29830 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
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View Lastest Price from ELEUTHEROSIDE A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-02 | Daucosterol
474-58-8
|
US $41.00-97.00 / mg | 99.03% | 10g | TargetMol Chemicals Inc. | ||
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2025-12-12 | ELEUTHEROSIDE A
474-58-8
|
US $1.00-22.00 / KG | 1KG | 99% | 100000KG | Shaanxi Dideu Medichem Co. Ltd | |
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2023-02-24 | Eleutheroside A
474-58-8
|
US $0.00 / mg | 5mg | ≥95%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-

- Daucosterol
474-58-8
- US $41.00-97.00 / mg
- 99.03%
- TargetMol Chemicals Inc.
-

- ELEUTHEROSIDE A
474-58-8
- US $1.00-22.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-

- Eleutheroside A
474-58-8
- US $0.00 / mg
- ≥95%(HPLC)
- Shanghai Standard Technology Co., Ltd.
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