Dimethyl adipate
- CAS No.
- 627-93-0
- Chemical Name:
- Dimethyl adipate
- Synonyms
- DIMETHYL HEXANEDIOATE;dbe-6;DIBASICESTERS;Adipic acid-di;Dimethyladipat;DIMETHYL ADIPATE;AKOS BBS-00004546;Flexisolv DBE-LVP;DBE 6 DIBASIC ESTER;Adipic acid dimethyl
- CBNumber:
- CB1412954
- Molecular Formula:
- C8H14O4
- Molecular Weight:
- 174.19
- MDL Number:
- MFCD00008469
- MOL File:
- 627-93-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Dimethyl adipate for synthesis | 8.00097 | 250ML | $46.1 |
| Dimethyl adipate for synthesis | 8.00097 | 1L | $135 |
| Dimethyl adipate ≥99% | 186252 | 100g | $50.4 |
| Dimethyl adipate ≥99% | 186252 | 500g | $128 |
| Dimethyl Adipate >99.0%(GC) | A0166 | 25mL | $21 |
| More product size | |||
| Melting point | 8 °C (lit.) |
|---|---|
| Boiling point | 109-110 °C/14 mmHg (lit.) |
| Density | 1.062 g/mL at 20 °C (lit.) |
| vapor pressure | 0.2 mm Hg ( 20 °C) |
| refractive index |
n |
| FEMA | 4472 | DIMETHYL ADIPATE |
| Flash point | 225 °F |
| storage temp. | Store below +30°C. |
| solubility | <1g/l |
| form | Liquid |
| color | Clear |
| Odor | at 100.00 %. mild nutty |
| Odor Type | nutty |
| explosive limit | 0.81-8.1%(V) |
| Water Solubility | Miscible with alcohols and ether. Immiscible with water. |
| Merck | 14,162 |
| JECFA Number | 1964 |
| BRN | 1707443 |
| Henry's Law Constant | 4.3×100 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases reducing agents. |
| Cosmetics Ingredients Functions |
SOLVENT PLASTICISER SKIN CONDITIONING - EMOLLIENT |
| Cosmetic Ingredient Review (CIR) | Dimethyl adipate (627-93-0) |
| InChI | 1S/C8H14O4/c1-11-7(9)5-3-4-6-8(10)12-2/h3-6H2,1-2H3 |
| InChIKey | UDSFAEKRVUSQDD-UHFFFAOYSA-N |
| SMILES | COC(=O)CCCCC(=O)OC |
| LogP | 1.4 at 22℃ |
| Substances Added to Food (formerly EAFUS) | DIMETHYL ADIPATE |
| CAS DataBase Reference | 627-93-0(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | BY71RX0R62 |
| NIST Chemistry Reference | Hexanedioic acid, dimethyl ester(627-93-0) |
| EPA Substance Registry System | Dimethyl adipate (627-93-0) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P280-P261 | |||||||||
| PPE | Eyeshields, Gloves | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | AV1645000 | |||||||||
| Autoignition Temperature | 680 °F | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29171290 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazardous Substances Data | 627-93-0(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in Rabbit: 8191 mg/kg LD50 dermal Rabbit > 2250 mg/kg | |||||||||
| NFPA 704 |
|
Dimethyl adipate price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.00097 | Dimethyl adipate for synthesis | 627-93-0 | 250ML | $46.1 | 2026-03-19 | Buy |
| Sigma-Aldrich | 8.00097 | Dimethyl adipate for synthesis | 627-93-0 | 1L | $135 | 2026-03-19 | Buy |
| Sigma-Aldrich | 186252 | Dimethyl adipate ≥99% | 627-93-0 | 100g | $50.4 | 2026-03-19 | Buy |
| Sigma-Aldrich | 186252 | Dimethyl adipate ≥99% | 627-93-0 | 500g | $128 | 2026-03-19 | Buy |
| TCI Chemical | A0166 | Dimethyl Adipate >99.0%(GC) | 627-93-0 | 25mL | $21 | 2026-03-19 | Buy |
Dimethyl adipate Chemical Properties,Uses,Production
Description
Dimethyl adipate (DMA) is a colourless and flammable liquid. It is soluble in alcohol and ether but sparingly soluble in water. DMA is incompatible with strong oxidising agents, and on decomposition, it emits carbon monoxide, irritating and toxic fumes and gases, and carbon dioxide. DMA reacts with acids, alkalis, and strong oxidants. DMA is synthesised by the esterification of adipic acid. DMA is part of a dibasic ester (DBE) blend used as a major ingredient in several paint strippers, and the DBE blends used in paint stripping formulations contain a major portion (about 90%) of DMA. DMA is used as a chemical intermediate (polymers, agrochemicals), cellulose resins, a speciality solvent (inks, coatings, adhesives), and an emollient and can also be utilised as a paint remover and plasticiser.
Chemical Properties
Dimethyl adipate is a colorless liquid. It is a fatty acid methyl ester.
Uses
Dimethyl adipate is used in cosmetics (in emollients and skin conditioning).It is used as a plasticizer for cellulose-type resins and a finish remover.It is also used in agrochemicals and dye as well as a precursor for the preparation of active pharmaceutical ingredients. Further, it serves as a polymer intermediate. In addition to this, it is employed as a solvent for paint stripping and resins.
Uses
Dimethyl adipate is used in cosmetics (in emollients and skin conditioning). It acts as a cosmetic plasticizer. It is also used in agrochemicals and dye as well as a precursor for the preparation of active pharmaceutical ingredients. Further, it serves as a polymer intermediate. In addition to this, it is employed as a solvent for paint stripping and resins.
Definition
ChEBI: Dimethyl adipate is a fatty acid methyl ester.
Production Methods
Dimethyl adipate is manufactured via esterification of adipic acid and methanol in the presence of an acid catalyst.
General Description
Colorless liquid.
Air & Water Reactions
Flammable. Hydrolyzed by strong mineral acids and strong alkalis.
Reactivity Profile
Dimethyl adipate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Health Hazard
May be harmful by inhalation, ingestion, or skin absorption. May cause irritation.
Health Hazard
Exposures to dimethyl adipate cause toxicity and adverse health effects in laboratory animals and humans. Workplace exposures to dimethyl adipate by inhalation, ingestion, or skin absorption cause harmful and irritation effects to users.
Flammability and Explosibility
Non flammable
Safety Profile
Moderately toxic by intraperitoneal route. Experimental teratogenic and reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
Synthesis
Dimethyl adipate was synthesized by immobilized Candida antarctica lipase B-catalyzed esterification of adipic acid and methanol.
According to the general procedure described above, Dimethyl adipate has been synthesized from adipic acid (730mg, 5 mmol) and methanol (10 ml). Yield: 9%.
1H NMR (400.1 MHz, CDCl3): δ = 3.56 (6H, s, H1-H10), 2.23 (4H, m, H4-H7), 1.56 (4H, m, H5-H6).
13C NMR (100.5 MHz, CDCl3): δ = 173.4 (C3-C8), 51.2 (C1-C10), 33.4 (C4-C7), 24.1 (C5-C6)
https://pubmed.ncbi.nlm.nih.gov/20632329/
Carcinogenicity
In a chronic inhalation toxicity study of dimethyl adipate, groups of male and female rats were exposed to 400 mg/m3 of dimethyl adipate over a 90-day period. Focal respiratory metaplasia of the olfactory epithelium was found. These nonneoplastic lesions were minimal to mild in severity .
Toxics Screening Level
The ITSL for Dimethyl Adipate is 1 μg/m3 based on annual averaging time.
Precautions
During handling of dimethyl adipate, occupational workers should be careful and use self-contained breathing apparatus, rubber boots, and heavy rubber gloves and avoid prolonged period of exposures. Workers should avoid contact of dimethyl adipate with skin, eyes and nose.
Dimethyl adipate Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 | info@fortunachem.com | China | 5975 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5235 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9333 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Hebei Youfeidi Trading Co., LTD | +8615530197691 | admin@yfdchem.cn | China | 105 | 58 |
| Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 661 | 58 |
| Hebei Yiduo Import and Export Co., Ltd. | joycedemei1505@outlook.com | China | 215 | 58 |
View Lastest Price from Dimethyl adipate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-24 | Dimethyl adipate
627-93-0
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-04-24 | Dimethyl adipate
627-93-0
|
US $0.00-0.00 / KG | 1KG | 99.96% | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2026-04-24 | Dimethyl adipate
627-93-0
|
US $1880.00 / T | 1T | 98% | 1-10mt | Baoji Guokang Healthchem Co., Ltd. |
-
- Dimethyl adipate
627-93-0
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Dimethyl adipate
627-93-0
- US $0.00-0.00 / KG
- 99.96%
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Dimethyl adipate
627-93-0
- US $1880.00 / T
- 98%
- Baoji Guokang Healthchem Co., Ltd.
627-93-0(Dimethyl adipate)Related Search:
1of4
