3-(4-Chlorophenyl)glutaric acid
- CAS No.
- 35271-74-0
- Chemical Name:
- 3-(4-Chlorophenyl)glutaric acid
- Synonyms
- CBI-BB ZERO/006271;Baclofen impurity C;Baclofen Impurity 3;Baclofen Impurity 1;Baclofen EP Impurity C;3-(4-chlorophenyl) glutarate;-(4-Chlorophenyl)glutaricacid;-(p-Chlorophenyl)glutaric Acid;b-(p-Chlorophenyl)glutaric Acid;3-(4-CHLOROPHENYL)GLUTARIC ACID
- CBNumber:
- CB1419706
- Molecular Formula:
- C11H11ClO4
- Molecular Weight:
- 242.66
- MDL Number:
- MFCD00190249
- MOL File:
- 35271-74-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-(4-Chlorophenyl)glutaricAcid | C378250 | 250mg | $95 |
| 3-(4-Chlorophenyl)glutaricAcid | C378250 | 1g | $120 |
| 3-(4-Chlorophenyl)glutaricAcid | C378250 | 5g | $135 |
| 3-(4-Chlorophenyl)glutaricAcid | C378250 | 10g | $155 |
| 3-(4-Chlorophenyl)glutaric acid | FC20344 | 500mg | $200 |
| More product size | |||
| Melting point | 164-166°C |
|---|---|
| Boiling point | 394.4±27.0 °C(Predicted) |
| Density | 1.396±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in dimethyl sulfoxide. Slightly soluble in methanol. |
| form | Solid |
| pka | 4.01±0.10(Predicted) |
| color | White to Light Yellow |
| BRN | 1976828 |
| InChI | InChI=1S/C11H11ClO4/c12-9-3-1-7(2-4-9)8(5-10(13)14)6-11(15)16/h1-4,8H,5-6H2,(H,13,14)(H,15,16) |
| InChIKey | URXVLIVRJJNJII-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CC(C1=CC=C(Cl)C=C1)CC(O)=O |
| CAS DataBase Reference | 35271-74-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| HazardClass | IRRITANT | |||||||||
| NFPA 704 |
|
3-(4-Chlorophenyl)glutaric acid price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C378250 | 3-(4-Chlorophenyl)glutaricAcid | 35271-74-0 | 250mg | $95 | 2021-12-16 | Buy |
| TRC | C378250 | 3-(4-Chlorophenyl)glutaricAcid | 35271-74-0 | 1g | $120 | 2021-12-16 | Buy |
| TRC | C378250 | 3-(4-Chlorophenyl)glutaricAcid | 35271-74-0 | 5g | $135 | 2021-12-16 | Buy |
| TRC | C378250 | 3-(4-Chlorophenyl)glutaricAcid | 35271-74-0 | 10g | $155 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC20344 | 3-(4-Chlorophenyl)glutaric acid | 35271-74-0 | 500mg | $200 | 2021-12-16 | Buy |
3-(4-Chlorophenyl)glutaric acid Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
3-(4-Chlorophenyl)glutaric Acid (cas# 35271-74-0) is a compound useful in organic synthesis. Baclofen Impurity 1
Synthesis
![Butanoic acid, 2-[(4-chlorophenyl)methylene]-3-oxo-, ethyl ester](/CAS/20210305/GIF/19411-80-4.gif)
19411-80-4
35271-74-0
The general procedure for the synthesis of 3-(4-chlorophenyl)glutaric acid using baclofen impurity 9 as starting material: the intermediate Π was dissolved in 420 mL of a 30 N aqueous solution of potassium hydroxide and the reaction was stirred for 2 hr at 85-90 °C. The reaction process was monitored by thin layer chromatography (TLC) and the unfolding agent was a mixture of ethyl acetate and petroleum ether (2:3, v/v). After completion of the reaction, the reaction mixture was cooled to room temperature and 400 mL of dichloromethane and 500 mL of deionized water were added sequentially. After stirring for 20 min, the organic and aqueous layers were separated and the organic layer was discarded. The aqueous layer was acidified to pH 1-2 with 6 M hydrochloric acid and the precipitated solid was subsequently filtered. The solid was washed with deionized water and dried under vacuum at 55-60°C for 5 h to give 157 g of white solid intermediate in 86.4% yield. The melting point of the intermediate was 166.5~167.3 °C.
References
[1] Patent: CN106187794, 2016, A. Location in patent: Paragraph 0023; 0028
3-(4-Chlorophenyl)glutaric acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Rokechem Technology Co., Ltd. | 18758118018 | sales001@rokechem.com | China | 255 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 4000 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20124 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29821 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 |
View Lastest Price from 3-(4-Chlorophenyl)glutaric acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-25 | 3-(4-Chlorophenyl)pentanedioic acid
35271-74-0
|
US $8.00-0.80 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2025-06-27 | 3-(4-Chlorophenyl)glutaric acid
35271-74-0
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-06-20 | 3-(4-Chlorophenyl)glutaric acid
35271-74-0
|
US $20.00 / kg | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. |
-
- 3-(4-Chlorophenyl)pentanedioic acid
35271-74-0
- US $8.00-0.80 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-(4-Chlorophenyl)glutaric acid
35271-74-0
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-(4-Chlorophenyl)glutaric acid
35271-74-0
- US $20.00 / kg
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
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