Terephthalaldehyde
- CAS No.
- 623-27-8
- Chemical Name:
- Terephthalaldehyde
- Synonyms
- 1,4-PHTHALALDEHYDE;Terephthaldehyde;1,4-BENZENEDICARBOXALDEHYDE;TEREPHTHALDICARBOXALDEHYDE;P-PHTHALALDEHYDE;TPAL;Benzene-1,4-dialdehyde;P-benzaldehyde;Terephtaldehyde;Terephthaladehyde
- CBNumber:
- CB1425781
- Molecular Formula:
- C8H6O2
- Molecular Weight:
- 134.13
- MDL Number:
- MFCD00006949
- MOL File:
- 623-27-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Terephthalaldehyde ReagentPlus , 99% | T2207 | 5g | $44.6 |
| Terephthalaldehyde ReagentPlus , 99% | T2207 | 100g | $81.7 |
| Terephthaldialdehyde for synthesis | 8.08617 | 100g | $86.1 |
| Terephthalaldehyde >98.0%(GC) | T0010 | 25g | $34 |
| Terephthalaldehyde >98.0%(GC) | T0010 | 100g | $102 |
| More product size | |||
| Melting point | 114-116 °C (lit.) |
|---|---|
| Boiling point | 245-248 °C (lit.) |
| Density | 1,06 g/cm3 |
| vapor pressure | 0.25-0.46Pa at 20-25℃ |
| refractive index | 1.4800 (estimate) |
| Flash point | 76 °C |
| storage temp. | Store below +30°C. |
| solubility | 3g/l |
| form | Crystalline Powder |
| color | White to light yellow |
| Water Solubility | 3 g/L (50 ºC) |
| Sensitive | Air Sensitive |
| BRN | 385863 |
| Henry's Law Constant | 1.6×101 mol/(m3Pa) at 25℃, Abraham and Jr. (2019) |
| Cosmetics Ingredients Functions | PRESERVATIVE |
| InChI | 1S/C8H6O2/c9-5-7-1-2-8(6-10)4-3-7/h1-6H |
| InChIKey | KUCOHFSKRZZVRO-UHFFFAOYSA-N |
| SMILES | [H]C(=O)c1ccc(cc1)C([H])=O |
| LogP | 1 at 20.1℃ and pH6.6-6.8 |
| CAS DataBase Reference | 623-27-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | M2Y6E4N2TS |
| NIST Chemistry Reference | 1,4-Benzenedicarboxaldehyde(623-27-8) |
| EPA Substance Registry System | 1,4-Benzenedicarboxaldehyde (623-27-8) |
| UNSPSC Code | 12352114 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36/37 | |||||||||
| Safety Statements | 22-24/25-36-26-37/39 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | WZ0430000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29122900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| Hazardous Substances Data | 623-27-8(Hazardous Substances Data) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Terephthalaldehyde price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T2207 | Terephthalaldehyde ReagentPlus , 99% | 623-27-8 | 5g | $44.6 | 2026-04-30 | Buy |
| Sigma-Aldrich | T2207 | Terephthalaldehyde ReagentPlus , 99% | 623-27-8 | 100g | $81.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.08617 | Terephthaldialdehyde for synthesis | 623-27-8 | 100g | $86.1 | 2026-04-30 | Buy |
| TCI Chemical | T0010 | Terephthalaldehyde >98.0%(GC) | 623-27-8 | 25g | $34 | 2026-04-30 | Buy |
| TCI Chemical | T0010 | Terephthalaldehyde >98.0%(GC) | 623-27-8 | 100g | $102 | 2026-04-30 | Buy |
Terephthalaldehyde Chemical Properties,Uses,Production
Description
Terephthalaldehyde is an aromatic dialdehyde. Theoretically, the two aldehydes of terephthalaldehyde (TPA) are equivalent, so the single or double Schiff base from TPA and d-glucosamine (Glc) may be formed at the same time. It is used as an intermediate for the preparation of dyes and fluorescent whitening agents and in the synthesis of polyimines by reacting with aliphatic diamines. It is also used as a precursor for the preparation of paramagnetic microporous polymeric organic frameworks (POFs) through copolymerization with pyrrole, indole, and carbazole. As a good crosslinking agent, it could used in crosslinked chitosan hydrogel for the selective removal of anionic dyes[1].
Chemical Properties
WHITE TO LIGHT YELLOW CRYSTALLINE POWDER
Uses
Terephthalaldehyde (cas# 623-27-8) is a compound useful in organic synthesis.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 3, p. 788, 1955
Tetrahedron Letters, 36, p. 2285, 1995 DOI: 10.1016/0040-4039(95)00191-E
Synthesis
Using p-xylene, carbon tetrachloride, azodiisobutyronitrile and chlorine as raw materials and solvents, chlorination to obtain benzyl chloride, and then oxidized under the catalytic effect of nitric acid and zinc nitrate, the addition of zinc nitrate improves the yield of terephthalaldehyde to more than 89%, and the purity of the product is higher than 99.0%. Chlorination hydrolysis usually uses highly toxic chlorine gas directly, which is very unfriendly to the environment. In order to avoid the direct use of chlorine gas, N-fluorobenzenesulfonamide and sodium chloride were firstly used to react with p-xylene to synthesize p-dichlorobenzene in a highly selective way, and then the crude product of terephthalaldehyde was obtained through the catalytic action of 98% concentrated sulfuric acid and manganese dioxide, and finally the oxidized masterbatch was neutralized by sodium hydroxide and the finished product of terephthalaldehyde was obtained by recrystallization from the mixture of ethanol and water with the yield of terephthalaldehyde of 77% by weight.
Purification Methods
Terephthalaldehyde [623-27-8] M 134.1, m 116o, b 245 -248o/771mm. Crystallise terephthalaldehyde from water. [Beilstein 7 IV 2140.]
References
[1] Weng Q, et al. Controllable Synthesis and Biological Application of Schiff Bases from d-Glucosamine and Terephthalaldehyde. ACS Omega, 2020; 5: 24864–24870.
Terephthalaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dalian Richfortune Chemicals Co., Ltd | +86-86-411-84820922 +86-8613904096939 | sales@richfortunechem.com | China | 305 | 57 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5228 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Hebei Longbang Technology Co., LTD | +86-18633929156 | admin@hblongbang.com | China | 972 | 58 |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 | L18532138899@163.com | China | 939 | 58 |
Related articles
- Terephthaldicarboxaldehyde: A Key Intermediate in Organic Synthesis
- Terephthaldicarboxaldehyde, is an aromatic dialdehyde with significant importance in the field of organic synthesis.
- Oct 22，2024
View Lastest Price from Terephthalaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-17 | Terephthalaldehyde
623-27-8
|
1kg | 98%min | 10000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-06-16 | Terephthalaldehyde
623-27-8
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
 |
2026-05-28 | Terephthalaldehyde
623-27-8
|
$8.00 | 1KG | 99% | 10 ton | Hebei Chuanghai Biotechnology Co,.LTD |
-
- Terephthalaldehyde
623-27-8
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Terephthalaldehyde
623-27-8
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- Terephthalaldehyde
623-27-8
- $8.00
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
623-27-8(Terephthalaldehyde)Related Search:
1of4
