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4-tert-Butylphenylboronic acid

CAS No.
123324-71-0
Chemical Name:
4-tert-Butylphenylboronic acid
Synonyms
AKOS BRN-0058;CAS:123324-71-0;RARECHEM AH PB 0112;4-tert-Butylphenylbo;P-tert-butylbenzeneboronic;4-T-BUTYLPHENYLBORONIC ACID;P-T-BUTYLPHENYLBORONIC ACID;4-t-Butylbenzeneboronic acid;4-tert-Butylphenylboronicaci;4-TERT-BUTYLPHENYLBORONIC ACID
CBNumber:
CB1432682
Molecular Formula:
C10H15BO2
Molecular Weight:
178.04
MDL Number:
MFCD01009697
MOL File:
123324-71-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:24
Product description Number Pack Size Price
4-tert-Butylphenylboronic acid ≥95.0% 480053 5g $28.5
4-tert-Butylphenylboronic acid ≥95.0% 480053 25g $65.1
4-tert-Butylphenylboronic Acid (contains varying amounts of Anhydride) B2251 5g $25
4-tert-Butylphenylboronic Acid (contains varying amounts of Anhydride) B2251 25g $92
4-t-ButylphenylboronicAcid B809363 2.5g $65
More product size

4-tert-Butylphenylboronic acid Properties

Melting point 191-196 °C (lit.)
Boiling point 296.7±33.0 °C(Predicted)
Density 1.02±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
pka 8.79±0.10(Predicted)
form Crystalline Powder
color White to off-white
BRN 5330959
InChI InChI=1S/C10H15BO2/c1-10(2,3)8-4-6-9(7-5-8)11(12)13/h4-7,12-13H,1-3H3
InChIKey MNJYZNVROSZZQC-UHFFFAOYSA-N
SMILES B(C1=CC=C(C(C)(C)C)C=C1)(O)O
CAS DataBase Reference 123324-71-0(CAS DataBase Reference)
UNSPSC Code 12352103
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-22-20/21/22-R36/37/38
Safety Statements  37/39-26-36-S37/39-S26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29163990
Storage Class 11 - Combustible Solids
NFPA 704
1
2 0

4-tert-Butylphenylboronic acid price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 480053 4-tert-Butylphenylboronic acid ≥95.0% 123324-71-0 5g $28.5 2026-04-30 Buy
Sigma-Aldrich 480053 4-tert-Butylphenylboronic acid ≥95.0% 123324-71-0 25g $65.1 2026-04-30 Buy
TCI Chemical B2251 4-tert-Butylphenylboronic Acid (contains varying amounts of Anhydride) 123324-71-0 5g $25 2026-04-30 Buy
TCI Chemical B2251 4-tert-Butylphenylboronic Acid (contains varying amounts of Anhydride) 123324-71-0 25g $92 2026-04-30 Buy
TRC B809363 4-t-ButylphenylboronicAcid 123324-71-0 2.5g $65 2021-12-16 Buy
Product number Packaging Price Buy
480053 5g $28.5 Buy
480053 25g $65.1 Buy
B2251 5g $25 Buy
B2251 25g $92 Buy
B809363 2.5g $65 Buy

4-tert-Butylphenylboronic acid Chemical Properties,Uses,Production

Chemical Properties

white to off-white crystalline powder

Uses

suzuki reaction

Uses

4-t-Butylphenylboronic acid is a cross-coupling building block used in the preparation of tetracyclnes and tetracycline derivatives.

Uses

Cross-coupling building block used in synthesis of tetracycline derivatives.

Synthesis

1-Bromo-4-tert-butylbenzene

3972-65-4

4-tert-Butylphenylboronic acid

123324-71-0

4-tert-butylbromobenzene was used as starting material and 4-tert-butylphenylboronic acid (4b) was synthesized according to the method described in literature [22] in 72.8% reaction yield. The resulting product was a white solid with a melting point of 158-160 °C (literature value: 160 °C). The structure of the product was confirmed by 1H NMR spectrum (CD3Cl as solvent, 300 MHz): δ 8.17 (d, 2H, J = 6.6 Hz), 7.42-7.54 (m, 2H), 1.38 (s, 9H).

References

[1] Tetrahedron Letters, 2003, vol. 44, # 30, p. 5747 - 5750
[2] Macromolecules, 2003, vol. 36, # 7, p. 2327 - 2332
[3] Organic and Biomolecular Chemistry, 2012, vol. 10, # 33, p. 6693 - 6704
[4] Dyes and Pigments, 2012, vol. 95, # 3, p. 679 - 688
[5] Journal of the Chemical Society. Perkin Transactions 2, 2001, # 11, p. 2166 - 2173

688-74-4
3972-65-4
123324-71-0
Synthesis of 4-tert-Butylphenylboronic acid from Tributyl borate and 1-Bromo-4-tert-butylbenzene
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View Lastest Price from 4-tert-Butylphenylboronic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-tert-Butylphenylboronic acid pictures 2026-04-30 4-tert-Butylphenylboronic acid
123324-71-0
US $171.50-4287.50 / kg 1kg ≥99.0% 10 tons Yancheng Green Chemicals Co.,Ltd
4-tert-Butylphenylboronic acid pictures 2025-09-25 4-tert-Butylphenylboronic acid
123324-71-0
US $34.00-1.20 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-tert-Butylphenylboronic acid pictures 2025-05-23 4-tert-Butylphenylboronic acid
123324-71-0
US $10.00 / kg 1kg 99% 20 ton Hebei Zhuanglai Chemical Trading Co Ltd
4-T-BUTYLPHENYLBORONIC ACID 4-TERT-BUTYLBENZENEBORONIC ACID 4-TERT-BUTYLPHENYLBORONIC ACID AKOS BRN-0058 RARECHEM AH PB 0112 P-T-BUTYLPHENYLBORONIC ACID [4-(1,1-Dimethylethyl)phenyl]boronic acid 4-t-Butylbenzeneboronic acid p-tert-Butylbenzeneboronic acid 4-tert-Butylphenylboronic acid (contains varying amounts of anhydride) 4-tert-Butylphenylboronic acid >=95.0% AKOS BRN-0058;4-T-BUTYLPHENYLBORONIC ACID;4-TERT-BUTYLBENZENEBORONIC ACID;4-TERT-BUTYLPHENYLBORONIC ACID;RARECHEM AH PB 0112;P-T-BUTYLPHENYLBORONIC ACID;4-TERT-BUTYLPHENYLBORONICACID97+%;4-TERT-BUTYLBENZENEBORONIC ACI 4-Tert-ButylphenylboronicAcid97+% 4-TERT-BUTYLBENZENEBORONIC ACID 97% 4-tert-Butylphenylboronic Acid (contains varying amounts of Anhydride) 4-tert-Butylbenzeneboronic acid ,98% 4-(tert-Butyl)phenylboronic acid, May contain varying amounts of anhydride, 97% 4-tert-Butylphenylbo 4-tert-Butylphenylboronic acid, 97% 5GR 4-TERT-BUTYLBENZENEBORONIC ACID; 4-(TERT-BUTYL)PHENYLBORONIC ACID para-tert-butylphenylboronic acid (p-tert-Butylphenyl)boronic acid 4-tert-Butylphenylboronic acid,98% Boronic acid, B-[4-(1,1-dimethylethyl)phenyl]- 4-tert-Butylphenylboronicaci 123324-71-0 4-tert-Butylphenylboronic acid CAS:123324-71-0 4-tert-Butylphenylboronic acid (4-(tert-Butyl)phenyl)boronic acid - [B2080] P-tert-butylbenzeneboronic 123324-71-0 12324-71-0 123324-79-4 CH33CC6H4BOH2 C10H15BO2 B (Classes of Boron Compounds) Boronic Acids BORONIC ACID Organometallic Reagents Aryl Boronic Acids and Derivatives Heterocyclic Compounds Boronic Acid Aryl Organoborons Substituted Boronic Acids Boron, Nitrile, Thio,& TM-Cpds Boronic Acids Boronic Acids and Derivatives B (Classes of Boron Compounds) Boronic acids blocks BoronicAcids Boronic Acid series