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AMAROGENTIN

AMAROGENTIN Structure
AMAROGENTIN structure
CAS No.
21018-84-8
Chemical Name:
AMAROGENTIN
Synonyms
AMAROGENTIN;Amarogentin-RM;Amarogentin Hydrate;Amarogentin from Gentia lutea;Amarogentin, 98%, from Gentiana scabra Bunge;(4aS)-6α-[2-O-[(3,3',5-Trihydroxy-1,1'-biphenyl-2-yl)carbonyl]-β-D-glucopyranosyloxy]-5β-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one;1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-4,4a,5,6-tetrahydro-6-[[2-O-[(3,3',5-trihydroxy[1,1'-biphenyl]-2-yl)carbonyl]-β-D-glucopyranosyl]oxy]-, (4aS,5R,6S)-;(2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate
CBNumber:
CB1452325
Molecular Formula:
C29H30O13
Molecular Weight:
586.54
MDL Number:
MFCD30541334
MOL File:
21018-84-8.mol
MSDS File:
SDS
Last updated:2026-02-02 18:10:39
Product description Number Pack Size Price
Amarogentin ≥98% 24914 1mg $32
Amarogentin ≥98% 24914 5mg $116
Amarogentin ≥98% 24914 10mg $184
Amarogentin ≥98% 24914 25mg $381
Amarogentin 361755 10mg $439
More product size
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AMAROGENTIN Properties

Melting point 229-230° (monohydrate)
alpha D20 -116.6° (methanol)
Boiling point 928.5±65.0 °C(Predicted)
Density 1.59±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: 1 mg/ml; DMSO: 2 mg/ml; PBS (pH 7.2): 0.1 mg/ml
pka 7.42±0.40(Predicted)
form A crystalline solid
color White to off-white
Major Application food and beverages
InChIKey FWSMZQZCMSGCCU-WKYWRJDANA-N
SMILES [C@@]12([H])CCOC(=O)C1=CO[C@@H](OC[C@@H]1[C@@H](O)[C@@H]([C@@H](O)[C@H](OC(=O)C3=CC(=C(C4C=CC=C(O)C=4)C(O)=C3)O)O1)O)[C@@H]2C=C |&1:0,10,13,14,16,17,19,40,r|
LogP 2.503 (est)
FDA UNII 5L82GT5I0W
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  WGK 3
Storage Class 11 - Combustible Solids
NFPA 704
0
2 0

AMAROGENTIN price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24914 Amarogentin ≥98% 21018-84-8 1mg $32 2024-03-01 Buy
Cayman Chemical 24914 Amarogentin ≥98% 21018-84-8 5mg $116 2024-03-01 Buy
Cayman Chemical 24914 Amarogentin ≥98% 21018-84-8 10mg $184 2024-03-01 Buy
Cayman Chemical 24914 Amarogentin ≥98% 21018-84-8 25mg $381 2024-03-01 Buy
Usbiological 361755 Amarogentin 21018-84-8 10mg $439 2021-12-16 Buy
Product number Packaging Price Buy
24914 1mg $32 Buy
24914 5mg $116 Buy
24914 10mg $184 Buy
24914 25mg $381 Buy
361755 10mg $439 Buy

AMAROGENTIN Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the dry roots and rhizomes of Gentiana Gentiana scabra Bge.

Uses

Amarogentin has the functions of protecting liver and gallbladder, inhibiting bacteria and diuretic.

Definition

ChEBI: Amarogentin is a secoiridoid glycoside that consists of (4aS,5R,6R)-5-ethenyl-6-hydroxy-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one having a 2-O-[(3,3',5-trihydroxybiphenyl-2-yl)carbonyl]-beta-D-glucopyranosyl group attached at position 6 via a glycosidic linkage. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a metabolite. It is a secoiridoid glycoside and a monosaccharide derivative.

in vivo

Amarogentin (100 mg/kg, p.o.) relieves Carbon tetrachloride (HY-Y0298)-induced liver fibrosis, decreases α-SMA and TGF-β1 expression in mice[1].

Animal Model:Carbon tetrachloride (HY-Y0298)-induced liver fibrosis mice model[1]
Dosage:100 mg/kg
Administration:p.o.
Result:Decreased hepatic α-SMA and TGF-β1 expression.
Inhibited phosphorylation of JNK, ERK, and p38.

target

TargetValue
TAS2R1
()
TNF-α
()
AMPK
()

AMAROGENTIN Preparation Products And Raw materials

Raw materials

Preparation Products

AMAROGENTIN Suppliers

Global( 179)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Bao Enluo International TradeCo.，LTD 		+86-17331933971 deasea125996@gmail.com China 2472 58
Shaanxi Xianhe Biotech Co., Ltd 		+86-17709210191; +8617709210191 Jerry@xhobio.com China 871 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29795 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 11727 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32470 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Supplier Advantage
Henan Bao Enluo International TradeCo.，LTD 		58
Shaanxi Xianhe Biotech Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Zheyan Biotech Co., Ltd. 		58
Chengdu Biopurify Phytochemicals Ltd. 		58
career henan chemical co 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
Wuhan ChemNorm Biotech Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58

View Lastest Price from AMAROGENTIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
AMAROGENTIN pictures 2026-02-24 AMAROGENTIN
21018-84-8
 US $0.00 / kg 1kg 0.99 1000kg Shaanxi Xianhe Biotech Co., Ltd
AMAROGENTIN pictures 2026-02-02 AMAROGENTIN
21018-84-8
 US $33.00-81.00 / mg 99.98% 10g TargetMol Chemicals Inc.
Amarogentin pictures 2023-06-16 Amarogentin
21018-84-8
 US $100.00 / kg 1kg 99% 500t/month Henan Bao Enluo International TradeCo.，LTD
  • AMAROGENTIN pictures
  • AMAROGENTIN
    21018-84-8
  • US $0.00 / kg
  • 0.99
  • Shaanxi Xianhe Biotech Co., Ltd
  • AMAROGENTIN pictures
  • AMAROGENTIN
    21018-84-8
  • US $33.00-81.00 / mg
  • 99.98%
  • TargetMol Chemicals Inc.
  • Amarogentin pictures
  • Amarogentin
    21018-84-8
  • US $100.00 / kg
  • 99%
  • Henan Bao Enluo International TradeCo.，LTD

AMAROGENTIN Spectrum

AMAROGENTIN(21018-84-8)1HNMR

21018-84-8(AMAROGENTIN)Related Search:

Valtrate 1α-(β-D-Glucopyranosyloxy)-1,4a,5,6,7,7aα-hexahydro-4aα-hydroxy-7α-methyl-5-oxocyclopenta[c]pyran-4-carboxylic acid methyl ester Amygdalin 4-Biphenylcarboxylic acid 3-Hydroxy-4-methylbenzoic acid
METHYL 3-HYDROXY-4-METHYLBENZOATE 3,5-Dihydroxy-4-methylbenzoic acid Methyl 4-phenylbenzoate AMAROGENTIN BIPHENYL-3-CARBOXYLIC ACID ETHYL ESTER
METHYL 3,5-DIHYDROXY-4-METHYLBENZOATE 3'-HYDROXYBIPHENYL-4-CARBOXYLIC ACID METHYL ESTER METHYL 5,5-DIMETHOXYVALERATE BENZYL BETA-D-GLUCOPYRANOSIDE AMAROGENTIN(P)
Amarogentin hexaacetate BETA-ISOBUTOXYACROLEIN 2-Ethoxy-3,4-dihydro-4-methyl-2H-pyran

1of4

(4aS)-6α-[2-O-[(3,3',5-Trihydroxy-1,1'-biphenyl-2-yl)carbonyl]-β-D-glucopyranosyloxy]-5β-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one Amarogentin from Gentia lutea Amarogentin, 98%, from Gentiana scabra Bunge Amarogentin Hydrate AMAROGENTIN 1H,3H-Pyrano[3,4-c]pyran-1-one, 5-ethenyl-4,4a,5,6-tetrahydro-6-[[2-O-[(3,3',5-trihydroxy[1,1'-biphenyl]-2-yl)carbonyl]-β-D-glucopyranosyl]oxy]-, (4aS,5R,6S)- (2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-(((3S,4R,4aS)-8-oxo-4-vinyl-3,4,4a,5,6,8-hexahydropyrano[3,4-c]pyran-3-yl)oxy)tetrahydro-2H-pyran-3-yl 3,3',5-trihydroxy-[1,1'-biphenyl]-2-carboxylate Amarogentin-RM 21018-84-8 21018-84-6 C27H28O14 C29H30O13